Sentences with phrase «cell transfer recipients»

CD8 + and CD8 − T cells were collected from either C57BL / 6 mice or adoptive cell transfer recipients one week after the rejection of BALB / c corneal allografts.

Not exact matches

When spleen CD4 + T - cells were transferred from heart - attack donor mice to naïve recipient mice, they induced long - term left ventricle dysfunction, fibrosis and enlargement, hallmarks of heart failure.

The patent gives California - based Geron Corp. exclusive rights to animal embryos prepared by transferring the nucleus of a quiescent diploid donor cell into a suitable recipient cell up to and including the blastocyst stage.

His team's approach is based on gene therapy, where a «tame» virus is harnessed to transfer a gene into target cells in the recipient.

Following the T cell transfer, the researchers infected the treated recipient mice with the bacteria.

The T cells were then transferred to recipient mice that, due to a genetic modification, could no longer produce immune cells of their own — similarly to patients suffering from leukemia.

In their work, the scientists were able to demonstrate that the transfer of just a few specific immune cells is sufficient to protect the recipient with the weakened immune system against infections.

MicroRNAs are transferred between cells via exosomes and influence the phenotypes of their recipient cells.

«The more rigid the particle, the easier it is likely taken up by cells, rendering exomeres, which are stiffer than exosomes, the more effective messengers of transferring tumor information to recipient cells.»

Indeed, our results indicate that adoptive transfer of CD8 + T cells from CD4 KO mice that had rejected corneal allografts resulted in the rejection of 95 % of the corneal allografts transplanted to athymic recipients.

Using the colitis transfer model, we showed that IL - 10 produced by a subset of myeloid cells in the Rag - / - recipients is required for colitis suppression by transferred Treg.

Hands - on Practical Training: Preparation of Media and Capillaries, Sperm Collection and Cryopreservation, Superovulation, Oviduct and Uterus Flushing, Handling and Culture of Preimplantation Embryos, In vitro Fertilisation, Controlled Freezing of 2 - cell embryos, Vasectomy, Plug Check of Recipients, Surgical Oviduct and Uterus Embryo Transfer

Three US - based scientists - Thomas Südhof, of Stanford University School of Medicine, Richard Scheller, of the biotech company Genentech, and James Rothman, of Yale University - are the joint recipients of the neuroscience prize for their work to reveal the precise molecular basis of the transfer of signals between nerve cells in the brain.

Embryos that developed to the 2 to 4 - cell stages were surgically transferred into synchronized recipient does (10 — 15 embryos per recipient).

(B) Ratio of LPA receptor - deficient (Lpar2 - / -, Lpar5 - / - or Lpar6 - / --RRB- cells to eGFP - expressing (WT) cells that migrated into the spleen, peripheral LN, and MLN after adoptive transfer into WT recipient mice.