Sentences with phrase «cell transfer techniques»

Several trials of adoptive T cell transfer techniques are currently under way for patients with breast cancer, including:

Several trials of adoptive T cell transfer techniques are currently under way for patients with head and neck cancer, including:

Several phase I and II trials of adoptive T cell transfer techniques are currently under way for patients with ovarian cancer, including:

Immunologists and oncologists are harnessing the body's immune system to fight cancers and other diseases with adoptive cell transfer techniques.

Not exact matches

One approach would be to identify immune cells in a tumour, grow them in a lab, and then infuse them back into the patient — a technique called adoptive cell transfer.

Even distantly related bacteria can swap genes with one another using a variety of techniques, from direct cell - to - cell transfer, called conjugation, to transformation, in which a bacterium releases snippets of DNA that other bacteria pick up and use.

CTL119 manufacturing begins with a patient's own T cells, some of which are removed and then reprogrammed in Penn's Clinical Cell and Vaccine Production Facility with a gene transfer technique designed to teach the T cells to target and kill tumor cells.

«Additionally, the most efficient perovskite solar cells are currently made through a process called solvent quenching — a technique that is not easily transferred from lab - scale deposition techniques to large - scale deposition techniques.

Zhong Zhong and Hua Hua are the product of somatic cell nuclear transfer (SCNT), the technique used to create Dolly the sheep over 20 years ago, in which researchers remove the nucleus from an egg cell and replace it with another nucleus from differentiated body cells.

Dolly made history as the first animal to be cloned from an adult cell using a technique known as somatic - cell nuclear transfer (SCNT).

He reported in May 2013 using the Dolly technique, known more formally as somatic cell nuclear transfer, to derive stem cells from cloned human embryos, including from a baby with an inherited disorder.

When the researchers used lab techniques to block this transfer, few egg cells were able to form.

Of the 29 early embryos created by somatic - cell nuclear transfer and implanted into various ewes by Roslin researchers, only one, Dolly, survived, suggesting that the technique currently has a high rate of embryonic and fetal loss.

The technique used by Wilmut and his co-workers — a technology called somatic - cell nuclear transfer — will probably be the way in which the first human clone will be created.

But the favored reprogramming technique, somatic cell nuclear transfer (SCNT), otherwise known as research cloning, is fraught with ethical pitfalls as well as technical difficulties because it entails creating a human embryo by inserting an adult cell nucleus into an ooctye.

Dolly was created using nuclear transfer, a technique in which an intact donor cell is fused with an egg whose nucleus had been removed.

In the new research, Prins and Liau used a technique called adoptive cell transfer, which involves extracting and growing immune cells outside of the body, then reprogramming them with a gene known as New York Esophageal Squamous Cell Carcinoma, or NY - ESO cell transfer, which involves extracting and growing immune cells outside of the body, then reprogramming them with a gene known as New York Esophageal Squamous Cell Carcinoma, or NY - ESO Cell Carcinoma, or NY - ESO - 1.

This is the mechanism underlying normal fertilization, as well as the cloning technique called Somatic - Cell Nuclear Transfer (SCNT).

Dolly was cloned using the technique of «somatic cell nuclear transfer,» when a nucleus from an adult cell is transferred into an unfertilized egg that has had its nucleus removed, and is then shocked with electricity to start cell growth.

Using a novel technique to genetically modify T cells for adoptive transfer, Carl June, Michael Kalos, David Porter, Bruce Levine, and colleagues at the University of Pennsylvania School of Medicine achieve clinical responses in patients with chronic lymphocytic leukemia, including two complete, durable (one year) clinical responses, accompanied by in vivo expansion and long - term functional persistence of gene - modified cells.

While Gurdon's tadpoles did not survive to grow into adult frogs, his experiment showed that the process of specialization in animal cells was reversible, and his technique of nuclear transfer paved the way for later cloning successes.

The same technique — injecting pluripotent stem cells into early embryos — failed with other combinations: The scientists couldn't create rat - pig chimeras, and although they produced human - cow chimeric embryos, they did not transfer them into cows to develop into fetuses.

This result was similar to recently published data from the Egli lab in New York, which used an alternative technique, that of maternal spindle transfer or MST in eggs prior to fertilization, where they also had one aberrant ES cell line where this occurred (out of 8).

The second method used somatic cell nuclear transfer (cloning techniques) to exchange all the mtDNA from the patient's cells with normal mtDNA from an egg donor in order to derive embryonic stem cells that are patient - specific with respect to nuclear DNA, but «rescued» with respect to mtDNA.

In Axel's lab, Littman embraced a then - novel technique for transferring genes into mammalian cells to parse their functions.

Once we can culture primordial germ cells and optimize germ - line transmission for Domestic Rock Pigeons, we can transfer those techniques to the Band - tailed Pigeon.

To whip up a human clone, doctors would most likely use a process called somatic cell nuclear transfer — the same technique they've used successfully with animals like Dolly, the famous (and now departed) sheep clone.

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The experiment that led to the cloning of Dolly the sheep in 1997 was different: It used a cloning technique called somatic cell nuclear transfer and resulted in an animal that was a genetic twin — although delayed in time — of an adult sheep.