Sentences with phrase «cell transplant centers»

City of Hope is one of the world's largest and most successful bone marrow and blood stem cell transplant centers.

Steven P. Margossian, MD, PhD Senior Physician, Stem Cell Transplant Center Dr. Margossian is a member of one of the largest pediatric stem cell transplant centers in the country and excels at helping children and families adjust during diagnosis and treatment.

Our Stem Cell Transplant Center is at the forefront of new, improved protocols for stem cell transplantation for blood - related disorders, including CSA.

Not exact matches

«Finding the optimal conditions to avoid interfering with immune cells working to eradicate cancer while preventing graft rejection and GVHD is the holy grail of bone marrow transplant,» says Leo Luznik, M.D., associate professor of oncology at the Johns Hopkins Kimmel Cancer Center.

Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.

Similar limbal stem cell transplant work has been done by physicians at the University of Melbourne's Center for Eye Research Australia and the Bernard O'Brien Institute of Microsurgery in Fitzroy, Australia.

The JDF Center for Islet Cell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantatCell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantatcell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantation.

Because previous work in rats and monkeys has found that proteins that block the costimulatory signal can hold T cells at bay, Kim Olthoff, a transplant surgeon at the University of Pennsylvania Medical Center in Philadelphia, thought her team could achieve a targeted immune suppression by getting the transplanted organ itself — rather than proteins injected into the bloodstream — to block the costimulatory signal.

«Preventing graft - versus - host disease and relapse after transplant requires a difficult balance of eliminating the bad, overactive effector T cells, without suppressing the good, regulatory T cells,» said Kean, who is also an associate professor of pediatrics at the University of Washington School of Medicine and a member of the Fred Hutchinson Cancer Research Center.

«Given the serious threat of graft - versus - host disease, new approaches to make stem cell transplants safer for patients remain a critical unmet need,» said Dr. Leslie Kean, the trial's principal investigator and associate director of the Ben Towne Center for Childhood Cancer Research at Seattle Children's.

«Because of relatively low survival rates and their advancing age, these patients tend to be poor candidates for aggressive therapies, like a bone marrow transplant,» said senior author Catriona Jamieson, MD, PhD, professor of medicine, chief of the Division of Regenerative Medicine at UC San Diego School of Medicine and director of the Stem Cell Research Program at Moores Cancer Center.

She ultimately chose to study leukemia patients» immune responses to bone marrow transplants, an area conducive to translational research in part because the work involves treating patients with human cells, which can be prepared at academic health centers.

Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

Acute GVHD is «entirely a T cell — mediated disease, most people would agree,» says Paul Martin, an oncologist and transplant veteran at the Fred Hutchinson Cancer Research Center (the Hutch) in Seattle, Washington.

The authors write that PBSCs are still used, despite disadvantages in patients with bone marrow failure, most likely because centers obtain PBSCs routinely for other indications and cell separators are available at any transplant center.

UT Southwestern Medical Center researchers created new nerve cells in the brains and spinal cords of living mammals without the need for stem cell transplants to replenish lost cells.

Yamanaka, 55, is now director of the Center for iPS Cell Research and Application (CiRA) at Kyoto University, which conducted the genetic analysis for the first iPS cells to be transplanted into a human.

An innovative experimental treatment for boosting the effectiveness of stem - cell transplants with umbilical cord blood has a favorable safety profile in long - term animal studies, report scientists from Dana - Farber Cancer Institute, Beth Israel Deaconess Medical Center (BIDMC), and Children's Hospital Boston (CHB).

A specialist in leukemia, lymphoma, and blood and marrow transplantation, Dr. Collins leads the Hematologic Malignancies / Blood and Marrow Transplantation Program and the combined Adult / Pediatric Stem Cell Transplant Program at UT Southwestern Medical Center.

Robert H. Collins Jr., M.D., FACP, is a Professor of Internal Medicine and Director of both the Hematologic Malignancies / Blood and Marrow Transplantation Program and the Combined Adult / Pediatric Stem Cell Transplant Program at UT Southwestern Medical Center.

«In essence, OX40 activates the IL - 9 gene in T helper cells, leading to the overproduction of IL - 9 through a powerful molecular machinery of super-enhancers that regulate gene expression,» says Dr. Xian C. Li, the director of the Immunobiology & Transplant Science Center at Houston Methodist Research Institute.

We offer a full spectrum of treatment services on site, including chemotherapy and radiation therapy, pre - and post transplant care for blood and bone marrow stem cell transplantation, as well as cancer screenings and supportive care services such as patient support groups and a cancer resource center.

However, most previous attempts to transplant blood stem cells into a human fetus have been unsuccessful, prompting some researchers to lose interest in this promising field, according to MacKenzie, who also is an investigator with the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research.

The Blood and Bone Marrow Stem Cell Transplant physicians are members of the nationally renowned University of Chicago Comprehensive Cancer Center (UCCCC), one of only two National Cancer Institute (NCI)- designated Comprehensive Cancer Centers in Chicago.

Experts in pediatric oncology, pediatric surgery, cell and gene therapy including stem cell transplant, radiation oncology, pediatric anesthesia, pharmacology, social work, child life and the full complement of pediatric subspecialty services put a strong focus on family - centered care and emotional support for both the child and the family.

The Emory Transplant Center has conducted clinical trials since 2003 transplanting human pancreatic islet cells into patients with Type I diabetes.

Patients requiring bone marrow transplantation receive treatment at the medical center's Rita J. and Stanley H. Kaplan Stem Cell and Bone Marrow Transplant Ccenter's Rita J. and Stanley H. Kaplan Stem Cell and Bone Marrow Transplant CenterCenter.

Images of hMito + (red) and GFAP (green) immuno - reactivity within hGDAsBMP (A, C, E, F) and hGDAsCNTF (B, D, G, H) transplants at the center of injury sites showing comparable densities of GFAP + intermediate filaments (green) within hMito immuno - positive cell bodies and process of both types of hGDAs.

When UC San Diego Jacobs Medical Center opens in 2016, blood and marrow transplant patients will have rooms with panoramic views and leading - edge treatments such as stem cell - directed clinical translational research.

Fabienne Lucas, MD PhD The Ohio State University Wexner Medical Center Columbus, OH Transplant as a Model for Accelerated T - Cell Aging

Up close, huddled inside the Centeno - Schultz Pain Center, I joined a team of MDs, a PhD, and two nurses to witness orthopedic history in vivo: an adult stem cell (ASC) transplant to help bones and joints grow anew.