Sentences with phrase «cell transplant patients»

Strengthen physical assessment skills essential for the care of pediatric and adolescent oncology, hematology and stem cell transplant patients

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Because a large portion of pediatric oncology and stem cell transplant patients» care occurs in ambulatory settings, the consortium is now focusing on understanding and reducing CLABSIs that originate in the home, between outpatient clinic visits.

«Common virus may help inform treatment planning for stem cell transplant patients.»

«This is such a prevalent virus... about 25 percent of stem cell transplant patients get infected [with rhinovirus] during the first year,» said Boeckh, who heads Fred Hutch's Infectious Disease Sciences Program.

It was originally developed by the Bavarian government and given to 150,000 German children in the 1970s; it has proved safe in more recent trials on HIV - positive people and stem - cell transplant patients.

Not exact matches

In the course of it, you lose hundreds of millions of muscle cells that won't be replaced, and instead less flexible scar tissue forms on the heart, which can lead to patients needing a heart transplant.

«Scientists say they have replaced a 65 - year - old patient's upper jaw with a bone transplant cultivated from stem cells isolated from his own fatty tissue and grown inside his abdomen.»

Researchers used stem cells to create retinal pigment epithelium cells, which were transplanted into a patient's retina (left) in an area depicted by the black circle.

Not only were there no adverse effects from the transplanted cells — this was primarily a safety trial — but 10 patients showed marked improvements in vision, and the eyesight in another seven seems to have stabilized.

For example, a consortium of research groups called the London Project to Cure Blindness aims to test RPE transplants from embryonic stem cells in patients with macular degeneration this year.

Luznik and his team inventoried types of immune cells present in the blood of bone marrow transplant patients treated with post-transplant cyclophosphamide.

Although drugs are available to replace thyroid function, with this new discovery, «we can now envision that thyroid function could be restored by transplanting patients» own thyroid cells,» said Hollenberg and Kotton.

Patients receiving standard immunosuppressive drugs after transplant, as opposed to high - dose cyclophosphamide, have slower recovery of regulatory T - cells in their blood, adds Kanakry.

It is similar to how radiation and chemotherapy are used to «condition» patients for a bone marrow transplant, to improve engraftment of transplanted immune cells.

Guo and his collaborators continue their studies by establishing additional mouse models of leukemia that have been transplanted with patient cells of relapsed and refractory disease.

The Boston patients, in contrast, are free of the virus thanks to a combination of a bone marrow transplant plus continuing antiretroviral drugs to stop newly donated immune cells from being infected.

Scientists are a step closer to creating blood stem cells that could reduce the need for bone marrow transplants in patients with cancer or blood disorders.

Zheng is planning a clinical trial to see if it could work for post-stem cell transplant AML relapse patients as well.

Targeting exhausted immune cells may change the prognosis for patients with acute myeloid leukemia (AML) relapse after a stem cell transplant, according to Penn State College of Medicine researchers.

Rashid's ultimate hope is that one day scientsts will be able to correct the diseased cells in the lab and transplant them back into the patient, but he cautions that cell - based therapies won't be available anytime soon.

U.S. biotechnology company Circe Biomedical has had similar success, she said, showing in an ongoing clinical trial of a similar device using pig liver cells that six out of 36 patients have completely recovered without the need for transplant.

Patients with severe and end - stage heart failure have few treatment options available to them apart from transplants and «miraculous» stem cell therapy.

Mice transplanted with cells grown from a patient suffering from Huntington's disease (HD) develop the clinical features and brain pathology of that patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.

Two men known only as the «Boston patients» have both stopped taking their anti-HIV medications following transplants of bone - marrow stem cells that appear to have banished the virus from their bodies.

Although such harvested cells could be cultured as say, liver cells for treating hepatitis or dopamine - producing cells for Parkinson's, the resulting transplants would likely be rejected by patients» immune systems.

Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.

«If you give patients immune cells to eradicate any remaining cancer cells that might be present,» he says, «those immune cells would not be prevented from doing their job by ongoing immune suppression drugs that are being used in patients treated with conventional transplant approaches.»

The cells were derived from eggs that had been injected with DNA from the patients, so they could eventually be transplanted back to replace or correct the patient's diseased cells without fear of immune rejection.

«This treatment is a new form of cell transplantation that utilizes the patient's own cells, so it does not require immunosuppressive drugs and, thus, avoids the side effects of those drugs,» says Scott Nyberg, M.D., Ph.D., a liver transplant surgeon at Mayo Clinic.

Diabetes researchers are considering various replacements for insulin injections: Transplanting new pancreatic islet cells that make insulin, coaxing the patient's own islets to regenerate, or treating diabetics early in the disease with immune - suppressing therapies to prevent their body from destroying the rest of their pancreatic islets.

In a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxic.

By reactivating telomerase activity in stem - cell derived tissue transplants, Geron could provide patients with a life - time warranty on their new parts.

Beta cells donated from deceased individuals have already been transplanted into diabetic patients through a procedure called the Edmonton protocol.

While some previous studies found that maintenance lenalidomide after autologous hematopoietic stem cell transplant improved overall survival for newly diagnosed multiple myeloma patients, others showed no benefit to this approach.

For this analysis, 605 patients with newly diagnosed multiple myeloma and treated with continuous lenalidomide (brand name Revlimid) following autologous stem cell transplant were compared to 604 patients who were treated with placebo or no maintenance.

Researchers can create iPSCs from a patient's blood or skin cells, and use these patient - specific cells to study diseases or even create new tissues that could be transplanted back into the patient as therapy.

June 2008 was the first time a patient received a trachea transplant that made use of her own stem cells, in what was then the most advanced example of tissue engineering.

Patients who develop this specific fungal infection are overwhelmingly adults who are immunocompromised, Kumar explains, including those with diabetes, transplant recipients, patients with cancer and those who have abnormally low concentrations of immune cells called neutrophils in theiPatients who develop this specific fungal infection are overwhelmingly adults who are immunocompromised, Kumar explains, including those with diabetes, transplant recipients, patients with cancer and those who have abnormally low concentrations of immune cells called neutrophils in theipatients with cancer and those who have abnormally low concentrations of immune cells called neutrophils in their blood.

Cancer patients undergoing stem cell transplantation face two hurdles: the short - term challenge of having enough white blood cells to fight possible infections immediately following the transplant and the long - term challenge of sustaining stem cell function to maintain immunity.

In the current study, almost 80 percent of the patients had undergone a previous stem cell transplant.

Omer, Tzannou and their colleagues conducted a clinical trial to determine the safety and effectiveness of pre-prepared virus - specific cells to treat five viral infections simultaneously in patients who had received a hematopoietic stem cells transplant.

A transplant of hematopoietic stem cells attempts to cure patients with certain cancers and other serious illnesses that have not responded to conventional chemotherapies.

Researchers infuse the patient with the organ donor's bone marrow in hopes that the donor's immune cells will teach the host to tolerate the transplant; donor immune cells that come along with the transplanted organ also, some contend, can teach tolerance.

With certain patients, however, these side - effects could be balanced out with stem - cell transplants, as in leukemia treatments.

Hwang claimed to have perfected somatic cell nuclear transplant, a procedure in which genetic material is removed from a donated egg and replaced with DNA from the patient to create cloned cells that could regenerate diseased tissues or organs.

«And, eventually it could lead to the development of cell transplant therapies that restore vision in patients with glaucoma and MS.»

This process multiplies the original SSCs by 18,000-fold so there are enough cells to transplant back into the patient when he reaches adulthood.

Scientists aim to freeze a sample of the boys» testicular tissue so that when they reach adulthood, spermatogonial stem cells (SSCs) found in the tissue can be reproduced and transplanted back into the patients.

In a preliminary trial of 23 type 1 diabetes patients, Burt found that stem cell transplants allowed 20 patients to stop their insulin shots for an periods ranging from a few months to five years, and counting, with an average of 30 months.