Sentences with phrase «cell transplantation approaches»

Not exact matches

In a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxic.

Dr. Cooper joined MDACC in 2006 as section chief of cell therapy at the Children's Cancer Hospital, where he cared for children undergoing bone marrow transplantation and led scientific efforts to develop new treatment approaches that pair genetic engineering with immunotherapies.

«Protection for the gut barrier: New approach may prevent graft - versus - host disease: Activating signal paths could protect patients from dangerous immune reactions after stem cell transplantations.»

As for treatments, the paper states, «Stem cell transplantation may prove to be a viable approach to treat diseases such as suPAR - associated kidney disease.»

However, coreceptor - specific ZFNs represent a novel therapeutic approach to recapitulate this success via autologous transplantation of gene - modified hematopoietic stem cells and mature CD4 + T cells.

Treatment approaches may include chemotherapy, radiation therapy, and rarely, stem cell transplantation.

Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:

Led by our faculty team of 25 physicians and scientists, our patients benefit from a team approach that includes our colleagues in radiology, surgery, radiation therapy, hematopathology, and stem cell transplantation, as well as clinical pharmacists, research and clinical nurses, social workers, and dietitians.

Dominic Eberle (Ader, TUD)-- «Cell transplantation and gene therapy approaches for the treatment of retinal degenerative disorders» (2012)

He noted that while no technique has emerged as a proven clinical approach, the use of human rather than rodent cells as demonstrated by Pollok et al. is an important step in advancing the science behind liver cell transplantation.

This approach has been reported to enhance the outcome of cell transplantation, due to increased cell retention in the site of transplantation.

In terms of which approaches people are taking which might bear fruit clinically most quickly; could you compare the transplantation encapsulation strategies with a stem cell based immune response - centered approach?

«Besides the applications this cell engineering and transplantation approach may find in regenerative medicine, our findings support the broader concept that enhancing the function of interneurons can counteract key aspects of Alzheimer's disease,» said Lennart Mucke, MD, director of the Gladstone Institute of Neurological Disease.

Acute myeloid leukemia (AML) is the leading cause of leukemia mortality in the United States.1 Curative treatment involves intensive induction chemotherapy, before proceeding to either consolidation chemotherapy or allogeneic stem cell transplantation based on the patient's risk for relapse.2 This approach has been employed for > 4 decades and, although most individuals achieve complete remissions with front - line therapy, 3 the majority of patients ultimately relapse with drug - resistant disease, and overall survival rates remain disappointingly poor.4 The limited ability of many patients to tolerate the intense chemotherapy - based treatments, in particular hematological toxicity, further contributes to the poor outcomes noted in this disease.