Sentences with phrase «cell transplantation in»

Although Tobi will never fully regain the use of his legs, he has benefitted from a clinical trial involving stem cell transplantation in dogs that is currently underway at North Carolina State University.

Their research focused on evaluating the safety and efficacy of autologous bone marrow - derived stem cell transplantation in individuals with type 2 diabetes with good glycemic control as well, which emerged as an important aspect in the transplantation group as well as in the non-transplanted group.

Previously the long - term benefits of hematopoietic stem - cell transplantation in cerebral adrenoleukodystrophy (ALD) are thought to be mediated by donor - derived replacement of myeloid derived cells, possibly including microglial cells.

Citation: Carr A-J, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LL, et al. (2009) Protective Effects of Human iPS - Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat.

Guido Silvestri, MD, division chief of Microbiology and Immunology at the Yerkes Research Center at Emory, and several of his research colleagues performed the first hematopoietic stem cell transplantation in three rhesus macaques infected with a simian human immunodeficiency virus (SHIV).

Promotion of Remyelination by Adipose Mesenchymal Stem Cell Transplantation in a Cuprizone Model of Multiple Sclerosis (July 2, 2013) in Cell Journal.

Children's Hospital Boston Harvard Medical School Chemotherapy and stem cell transplantation in leukemia

Review of «Biological markers of Mesenchymal Stromal Cells as Predictors of response to Autologous Stem Cell Transplantation in Patients with Amyotrophic Lateral Sclerosis; an Investigator - Initiated Trial and in Vivo Study» from Stem Cells by Stuart P. Atkinson

Accelerated aging of immune system after hematopoietic stem cell transplantation Researchers demonstrated that hematopoietic stem cell transplantation in patients with hematological malignancies significantly accelerates aging of immune system.

The role of hematopoietic stem cell transplantation in treatment of hemophagocytic lymphohistiocytosis.

Biological markers of Mesenchymal Stromal Cells as Predictors of response to Autologous Stem Cell Transplantation in Patients with Amyotrophic Lateral Sclerosis; an Investigator - Initiated Trial and in Vivo Study.

Bauer G and Anderson JS Stem cell transplantation in the context of HIV — how can we cure HIV infection?

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis.

Bornhäuser M, Kienast J, Trenschel R, et al Reduced - intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open - label randomised phase 3 trial.

Stem cell transplantation in general, using donor cells from either bone marrow, mobilized blood, or cord blood has become a more common practice over the last twenty years.

They acknowledge modest benefit from hematopoietic stem cell transplantation in cardiac disease and ameliorative but noncurative outcomes in autoimmune diseases.

«But, based on our data, we believe there is a case for early intervention with personalized antiviral treatments following stem cell transplantation in order to suppress hCMV reactivation.»

Journal reference: JAMA, C - Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus

The article described how a team of researchers, surgeons and radiologists had successfully carried out a number of islet cell transplantations in people with Type 1 diabetes, in Edmonton, Canada..

Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study.

A major breakthrough in the development of stem cell - derived brain cells has put researchers on a firm path towards the first ever stem cell transplantations in people with Parkinson's disease.

A major breakthrough in the development of stem cell - derived brain cells towards the first ever stem cell transplantations in people with Parkinson's disease

Not exact matches

Previously, Dr. Nikolic was an Assistant Professor in Medicine at Harvard Medical School where he led an advanced immunology laboratory for tolerance induction and stem - cell transplantation at Massachusetts General Hospital / Harvard Medical School.

The difficulties associated with obtaining nerve tissue at the correct stage of development and differentiation from aborted embryos means that foetal tissue transplantation is no longer in favour, but the creation of human embryos specifically as sources of stem cells, and the push to use «spare» embryos from IVF treatments is gatheringmomentum.

Over the last 15 years, there have been no successful clinical trials in which fetal cell transplantation into patients resulted in patient improvement.

Rocco Bavuso, left, 22, of Bayside, who was diagnosed with aplastic anemia, meets Christian Verholen, 32, his marrow doner, on May 8, 2018, at the annual Celebration of Life Dinner of North Shore University Hospital's Don Monti Bone Marrow and Stem Cell Transplantation Program at Crest Hollow Country Club in Woodbury.

Islet cell transplantation research in the UK The success of a novel islet transplantation procedure, called the «Edmonton protocol» was reported in an article in the New England Journal of Medicine, 27 July 2000.

It is possible that spider silk could also be used in future for other neurological diseases where cell transplantation plays a role.

Stem cells in babies» urine seem to help regenerate kidney tissue, protecting it from toxic drugs and could pep up organs for transplantation

Lanza, a physician who had spent the past 20 years working in academic research and biotech on organ and cell transplantation, was one of West's first recruits.

In a study in the current issue of the Journal of Neuromuscular Diseases, researchers treated these stem cells with leukemia inhibitory factor (LIF), which effectively maintained the undifferentiated state of the satellite cells and enhanced their transplantation efficiencIn a study in the current issue of the Journal of Neuromuscular Diseases, researchers treated these stem cells with leukemia inhibitory factor (LIF), which effectively maintained the undifferentiated state of the satellite cells and enhanced their transplantation efficiencin the current issue of the Journal of Neuromuscular Diseases, researchers treated these stem cells with leukemia inhibitory factor (LIF), which effectively maintained the undifferentiated state of the satellite cells and enhanced their transplantation efficiency.

In addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioIn addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin their own labs to study heart disease and issues with transplantation.

But because yeast does not contain restriction - modification systems, such transplantation poses problems not encountered in transplantation from one bacterial cell to another.

An update search enlarged the pool of study data, but did not change the content of the conclusion of the benefit assessment of stem cell transplantation (SCT) for multiple myeloma conducted in 2012.

To have enough cells for transplantation, they must be grown in vitro and prevented from differentiating before transplantation.

Investigations aimed at determining the downstream targets of LIF would help to clarify the functional importance of LIF in muscle regeneration, and further its potential application in cell transplantation therapy.»

«Due to the inhibitory function of Treg cells, people have been trying to use these cells for therapy in human autoimmune diseases or transplantation,» explains professor Yun Cai Liu, Ph.D., who led the current study.

In a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxiIn a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxiin the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxiin collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxiin mice, an approach they hope will make blood stem cell transplants for these patients far less toxic.

UTSW co-authors include: Co-lead author Maria Winter, a research associate; Dr. Luisella Spiga, a postdoctoral researcher; visiting fellow Lisa Büttner; graduate students Elizabeth Hughes and Caroline Gillis, all of Microbiology; Dr. Breck Duerkop, Instructor, Immunology; Cassie Behrendt, a research technician, Immunology; Dr. Lora Hooper, Professor and Chair of Immunology with appointments in Microbiology and in the Center for the Genetics of Host Defense, a HHMI Investigator and holder of the Jonathan W. Uhr, M.D. Distinguished Chair in Immunology, and the Nancy Cain and Jeffrey A. Marcus Scholar in Medical Research, in Honor of Dr. Bill S. Vowell; Dr. Luis Sifuentes - Dominguez, Instructor of Pediatrics; Dr. Kayci Huff - Hardy, clinical fellow, Internal Medicine in the Division of Digestive and Liver Diseases; Dr. Andrew Koh, Associate Professor of Pediatrics and Microbiology and in the Harold C. Simmons Comprehensive Cancer Center as well as Director of Pediatric Hematopoietic Stem Cell Transplantation at Children's Health; and Dr. Ezra Burstein, Professor of Internal Medicine and Molecular Biology and Chief of the Division of Digestive and Liver Diseases.

The researchers have now reported in the journal Nature that the normal process of blood formation differs from what scientists had previously assumed when using data from stem cell transplantations.

«The ability to control autoimmunity by autologous HSCT [hematopoietic stem cell transplantation] has been demonstrated in other treatment - refractory autoimmune conditions, including neurologic diseases.

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

In order to overcome the limited ability of the neurons of the adult nervous system to regenerate spontaneously, cell replacement strategies employing embryonic tissue transplantation show attractive potential.

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin (ANG) that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation - induced bone marrow failure.

The capsule creates the biotechnical condition for it, because it separates the donator's cells from the body of the receiver and transfers the hormones which are important for the metabolism exclusively «In the eyes of Dresden scientists this kind of transplantation will be suitable for patients with adrenal insufficiency but also with congenital diseases such as the lack of 21 - hydroxylase.

«To date, there has been no systematic means of assessing the fidelity of cellular engineering — to determine how closely cells made in a petri dish approximate natural tissues in the body,» says George Q. Daley, MD, PhD, Director of the Stem Cell Transplantation Program at Boston Children's and senior investigator on both studies.

He noted that before physicians and scientists begin offering SSC transplantation in patients, additional research will be needed, including whether other types of leukemia cells will also be eliminated in the cell - propagation process.

«Stem cells must be carefully preserved to keep them alive and functioning until the time of transplant, and there are some risks involved in cell transplantation.

Transplantation of pancreatic islets — cell clusters that contain insulin - producing cells — prevents severe, potentially life - threatening drops in blood sugar in people with type 1 diabetes, according to new research.

New clinical trial results show that transplantation of pancreatic islets — cell clusters that contain insulin - producing cells — prevents severe, potentially life - threatening drops in blood sugar in people with type 1 diabetes.