Sentences with phrase «cell transplants showed»

«Stem cell transplant shows «landmark» promise for treatment of degenerative disc disease.»

Not exact matches

Not only were there no adverse effects from the transplanted cells — this was primarily a safety trial — but 10 patients showed marked improvements in vision, and the eyesight in another seven seems to have stabilized.

Final results won't be out until 2013, and they will show mainly whether the cell transplants are safe.

Jacob's team has transplanted the back - up or «alternative» respiratory machinery from the mitochondria of lower organisms to human cells, showing that it can protect against pathological stresses, and even lethal poisons like cyanide, that target the mitochondria.

U.S. biotechnology company Circe Biomedical has had similar success, she said, showing in an ongoing clinical trial of a similar device using pig liver cells that six out of 36 patients have completely recovered without the need for transplant.

«Novel type 1 diabetes treatment shown to work on human beta cells transplanted into mice.»

«Stem cell transplant without radiation or chemotherapy pre-treatment shows promise.»

While some previous studies found that maintenance lenalidomide after autologous hematopoietic stem cell transplant improved overall survival for newly diagnosed multiple myeloma patients, others showed no benefit to this approach.

In 1988 and 1989 at Edouard Herriot Hospital, two fetuses whose blood cell markers showed they had severe immune disorders became the first ever to receive a cell transplant.

The results show that germline stem cells can indeed restore fertility when transplanted into other mice, Wu says.

A variety of agents have been shown to induce transplanted stem cells to differentiate into neurons.

The results show that the transplanted stem cells act as a «bridge» which allows injured sensory nerve fibers to grow into the spinal cord, rebuild functional nerve connections, and thereby achieve long term restoration of major parts of the lost sensory functions.

The results, which are published in the scientific journal Scientific Reports, show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions.

Experience with lymphoma patients, who receive a transplant of their own blood or bone cells after radiation to wipe out their cancer, has shown «there's no doubt it helps,» says bone marrow transplant expert Nelson Chao of Duke University in Durham, North Carolina.

Sacha's team has shown a species of monkey called Mauritian cynomolgus macaques can successfully receive stem cell transplants.

The scientists have been able to show that the corneal epithelial cells can be cultivated and transplanted onto the eyes of rabbits with experimentally induced blindness to surgically repair the front of the eye.

Now, researchers at the University of Missouri have shown that a new line of genetically modified pigs will host transplanted cells without the risk of rejection.

He began to show immediate improvement and after three cycles of treatment received a blood stem cell transplant, and since has been cancer free for 19 months.

Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

Furthermore, when the team suppressed STAP - 2, the prostate cancer cells showed reduced proliferation and did not form a tumor when transplanted into mice.

They went on to show that the cells — when moved to new conditions — could then be coaxed to develop into functional nephron - like structures both in the lab or when transplanted into animals.

In this study, the researchers also showed that they could grow tumor cells from patients into organoids that could be transplanted into mice.

Using stem cells harvested from human bone marrow, researchers transplanted cells into mice modeling ALS and already showing disease symptoms.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.

But first, notes Gepstein, research will have to show that the transplanted cells can keep working over many years.

To test whether the cells would maintain their multipotency in living animals, the researchers transplanted them into mice whose white blood cells had been depleted, and showed that the new cells could expand and differentiate into various types of white blood cells.

Previous work from the Cambridge team has shown that transplanting neural stem cells (NSCs)-- stem cells that are part - way to developing into nerve cells — reduces inflammation and can help the injured CNS heal.

UC Davis researcher Min Zhao and Junfeng Feng, a neurosurgeon at Ren Ji Hospital, Shanghai, showed that they can steer transplanted stem cells (green, in inset on right) to one part of a rat's brain using electrical fields.

Bright field and fluorescent images show the location of transplanted cells.

Transplanted cells were labeled with a red dye, while a perfused green dye shows the extent of functional blood vessels.

Most of the diseases treated by stem cell transplant are rare among children; however recent trials with cord blood have shown promise for stem cell therapy treating more common childhood conditions such as cerebral palsy, autism and others.

The new report, co-authored by several international research groups and led by Karolinska Institutet, shows that stem cells transplanted into damaged or threatened nerve tissue quickly establish direct channels, called gap junctions, to the nerve cells.

We show that subpopulations of human astrocytes, generated by activation of different signaling pathways in the same population of human glial precursor cells, have markedly different effects when transplanted into the injured spinal cord.

The distribution and density of hMito + mitochondria within individual hGDAs was sufficient to identify their cell bodies and show that both types of hGDA often displayed similar typical astrocytic «stellate» arrangements of their processes within transplant parenchyma, gray matter and white matter (Fig. 2 E and F, Fig. 3 A and B, Fig. 4 C).

Images of hMito + (red) and GFAP (green) immuno - reactivity within hGDAsBMP (A, C, E, F) and hGDAsCNTF (B, D, G, H) transplants at the center of injury sites showing comparable densities of GFAP + intermediate filaments (green) within hMito immuno - positive cell bodies and process of both types of hGDAs.

Several human clinical trials have now shown that stem cells can be transplanted into the eye.

Results from a recent trial of this technique in a SCID disorder show 100 % survival rates at 7 years post-treatment, xvi compared with 85 % survival in patients receiving a stem cell transplant from a healthy sibling.

Half - Matched Transplants May Cure More Than Cancer Bone marrow transplant researchers showed that half - matched (haploidentical) bone marrow transplants can cure sickle cell anemia, a painful and debilitating blood - forming disease that primarily affects African -Transplants May Cure More Than Cancer Bone marrow transplant researchers showed that half - matched (haploidentical) bone marrow transplants can cure sickle cell anemia, a painful and debilitating blood - forming disease that primarily affects African -transplants can cure sickle cell anemia, a painful and debilitating blood - forming disease that primarily affects African - Americans.

This is the «show reel» of Dr Haluk Deda, a Turkish neurosurgeon who is setting up shop in Dubai, where he plans to offer autologous stem cell transplants to treat chronic spinal cord injuries and ALS, a condition with no known cure that generally leads to death within three to five years of diagnosis.

Earlier studies had shown that when normal cells are transplanted into such mice, they are quickly converted into a diabetic state.

Mini Transplant May Reverse Severe Sickle Cell Disease Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that «mini» stem cell transplantation may safely reverse severe sickle cell disease in aduCell Disease Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that «mini» stem cell transplantation may safely reverse severe sickle cell disease in aducell transplantation may safely reverse severe sickle cell disease in aducell disease in adults.

Inset shows higher resolution confocal images of photoreceptor cell nuclear layers (DAPI blue) and rhodopsin expression (red) in the dystrophic control (left inset) and dystrophic with iPS - RPE transplant (right inset) RCS rat.

One study presented in the journal — from a group led by Patrick Singleton, PhD, assistant professor of medicine at the University of Chicago Medicine — shows how opioids already present in the body can enhance the malignant tendencies of human lung cancer cells transplanted into mice, even without the addition of morphine.

In addition to showing no survival difference between transplant recipients who received bone marrow or peripheral stem cells, the study showed no difference in relapse rates, mortality unrelated to relapse or rate of acute GVHD.