Federal officials have approved the start of human embryonic stem
cell treatment experiments on patients suffering a leading cause of vision loss.
Not exact matches
In
experiments with mouse ovaries inhibiting the identified enzymes saved the oocytes from
cell death despite
treatment with chemotherapeutics.
The
experiments reveal that the sudden loss of energy supply to the heart
cells and the subsequent rapid «reboot» during
treatment causes mitochondria to falter and trigger a whirlwind of aberrant electrical signals.
The
experiment Orwig has in mind is to use gene - editing technology to fix this flaw in the sperm - forming stem
cells and then transplant them back into infertile mice, thereby demonstrating a potential
treatment for male infertility.
The
treatment can also easily kill cancer
cells, but in this
experiment, it was vital to specifically show that it virtually halts
cell migration.
The
treatment did a lot to prevent
cell migration, a key mechanism in metastasis, in
experiments on laboratory cultures (in vitro) of cancerous human
cells.
The experimental
treatment also spared healthy
cells, in these and in prior
experiments, making the method potentially much less taxing on patients than commonly used chemotherapy.
Together, Raman says, this dual - mode
treatment produced
cell - killing results that paralleled their
experiments in
cell cultures.
For example, the flagship journal of the Public Library of Science, PLOS ONE, was the only journal that called attention to the paper's potential ethical problems, such as its lack of documentation about the
treatment of animals used to generate
cells for the
experiment.
All six mice with pancreatic cancer were still alive at the end of the
experiment, 113 days after
treatment with 5E5 CAR T
cells.
In laboratory
experiments, researchers at Karolinska Institutet in Sweden demonstrate that estrogen
treatment and overexpression of the estrogen receptor cause malignant neuroblastoma
cells to mature into neuron - like
cells.
«Our
experiments indicate that after stem
cell treatment, mouse eyes that initially had corneal defects looked no different than mouse eyes that had never been damaged,» Dr. Funderburgh said.
Moreover, the allospecific apoptotic activity of the putative DN T
cells was abolished in two separate
experiments using in vitro
treatment with anti-Thy 1.2 antibody plus complement, which removed > 97 % of the Thy 1 +
cells, as determined by flow cytometry.
In our preliminary
experiments, using increasing concentrations of doxorubicin,
treatment of ALCL
cells with 1 μmol / L doxorubicin resulted in no change in
cell viability.
The recently discovered protein NUDT5 is now presented as a candidate target for development of breast cancer
treatment after being demonstrated to stop breast tumor
cell growth in laboratory
experiments.
Government regulators have given the go - ahead to a second study that will for the first time carefully test a
treatment created using human embryonic stem
cells in people, according to the company sponsoring the
experiment.
The gelatinolytic assays were carried out in two different ways to obtain complementary information: firstly,
cells were treated or not with the test compound and samples from these were submitted to gelatinase zymography to detect the effects of the kahweol
treatment on the expression of gelatinase activities; secondly, in some
experiments, samples from control, untreated HT - 1080 fibrosarcoma
cells were submitted to zymography and, after electrophoresis, different concentrations of kahweol were added to the substrate buffer to determine the potential direct effect of kahweol on gelatinase activity.