Sentences with phrase «cell treatment reduces»

A recent study found that human stem cell treatment reduces alcohol abuse in rats.

Various studies demonstrated that stem cells treatment reduced scar burden, affected fibroblast proliferation, reduced Type I and Type III Collagen synthesis, improved ventricular function and affected left ventricular geometry.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

A 50,000 unit blood bank would provide economies of scale that would reduce the cost to the NHS for every treatment as well as radically reducing the need to import stem cell units from abroad, which is a common and expensive practice today.

Anti-hormone therapy is a commonly prescribed treatment for cancer of the prostate, which helps to reduce the levels of male hormones — that stimulate cancer cells to grow — in the gland.

Once the nanoparticles reach the cancer cells» mitochondria, the researchers apply near infrared laser treatment to trigger a chemical reaction that reduces the amount of ATP available to the pumps and, thus, cuts off their power supply.

Subsequent tests revealed that the treatment had reduced the visible cell population by a factor of 100 thousand, compared with an untreated cell culture, within the space of just 20 days.

Professor Rudi Beyaert (VIB / UGent): «We found that pharmacological treatment of human skin cells with drugs that inhibit the activity of MALT1 reduced the production of inflammation promoting proteins caused by mutant variants of CARD14.

Compared to a control (left), epalrestat treatment (right) reduces the number of metastatic tumors (arrowheads) in the lungs of mice injected with human basal - like breast cancer cells.

When scientists were able to prevent the excessive neurogenesis which occurs within days of the injury with a drug similar to one under trial for chemotherapy treatments, the rate of birth of new brain cells went back to normal levels and risk for seizures was reduced.

In BRCA - deficient cells, treatment with the molecule resulted in reduced cell growth and viability.

Treatment of vestibular schwannoma cells with mifepristone reduced their proliferation rate by 80 percent.

B cell treatment also quickly reduced the size and improved the healing of chronic skin ulcers in the diabetic mice, increasing the number of both nerve endings and blood vessels in regenerated tissue.

«Cancer doesn't sleep: MYC oncogene disrupts clock, metabolism in cancer cells: Findings inform time - dependent treatment for reducing side effects, increasing effectiveness of cancer medications.»

Kwon Tae You explains «4EGI - 1 treatment reduced the protein synthesis rate by about 50 %,» and when the cells were re-seeded in fresh ESC medium, the 4EGI -1-treated cells showed a reduced capacity to re-establish colonies.

Although fewer activated T cells were generated after a treatment with 3pRNA, the positive effect of the leukemia therapy was not reduced to a measurable degree.

In animal models, the modified T cells greatly reduced the tumor burden and prolonged overall survival: All mice that received the modified T cells were alive 44 days after treatment versus 29 percent and 17 percent of the study's two control groups.

Thus, when the drug treatment reduces the availability of a particular nutrient, the flexible cancer cells can feed themselves with an alternative energy source.»

Future treatment of OS patients with this type of antibody could reduce amputations among young patients and future studies will clarify if such a treatment strategy will also block lethal spreading of the OS cells to other organs.

This visual abstract depicts how Wei et al. utilize single - cell phosphoproteomic analysis of patient derived glioblastoma models to identify shifts in signaling coordination following short - term treatment with kinase inhibitors, which facilitates the design of combination therapy approaches with reduced resistance and improved efficacy.

The discovery of the anxiety cells raises the possibility of finding treatments that target them and reduce anxiety.

Apte, also a professor of developmental biology, of medicine and of neuroscience, said that all current treatments for glaucoma are aimed at lowering pressure in the eye to reduce ganglion cell loss and not necessarily at directly preserving ganglion cells.

He says that the new nanoparticles accumulate preferentially in tumors, which could drastically reduce the side effects of current cancer treatments that usually kill healthy cells along with the targeted cancer cells.

Clinical translation is the obvious answer, and hopefully this research will represent an important step in reducing the risk of stem cell treatment for diabetes, as well as other diseases.

«The study in Nature shows that after a heart attach in mice, treatment with specially engineered cells can reduce this potentially lethal rhythm disturbance.

The first reports that gene - editing of bone marrow stem cells in monkeys infected with a variant of simian immunodeficiency virus (SIV) significantly reduces the number Read more about Gene - editing and vaccines could improve HIV treatment - Scimex

Flow cytometry analysis showed that, compared with control, VPA treatment markedly reduced the frequencies of Th1 and Th17 cells in the spleen (Fig. 2C, 2D) and MLN (Supplemental Fig. 3A, 3B).

In this study, we demonstrate that VPA treatment ameliorated GVHD in a mouse BMT model by downregulating Th1 and Th17 cells and reducing inflammatory cytokine levels via inhibition of the phosphorylation level of Akt in CD4 + T cells.

Heretofore, treatment of patients with primary or light chain - associated (AL) amyloidosis has been directed toward reducing the synthesis of the amyloidogenic precursor protein through conventional or high - dose cytotoxic antiplasma cell chemotherapy.

Furthermore, he demonstrated that a class of drugs often used in the treatment of diabetes also reduces the harmful effects of white fat cells on bones.

There are many types, and certain cancer treatments (including chemotherapy) reduce the number of these cells.

Radiation therapy may be used to reduce the size of a cancer before surgery, to destroy any remaining cancer cells after surgery, or, in some cases, may be the main treatment.

The Regenexx ® family of non-surgical stem - cell & blood platelet procedures are next generation regenerative injection treatments for those who are suffering from pain, inflammation or reduced range of motion due to common elbow injuries, arthritis and overuse conditions.

Results: Fibroblast growth factor 2 (FGF2) treatment reduced expression of β - cell markers, (INS, MAFB, SLC2A2, SLC30A8, and GCK) and activated ectopic expression of MYC, HES1, SOX9, and NEUROG3.

This would prevent the toxicity seen when patients are treated with systemic immune - boosting therapies and reduce the need for multiple rounds of T - cell treatment.

The Regenexx ® family of non-surgical stem - cell & blood platelet procedures are next generation regenerative injection treatments for those who are suffering from pain or reduced range of motion due to basal joint / cmc arthritis, hand arthritis, or other injuries & conditions in the hand.

Using these cells, she will see how reducing or increasing the presence of PIAS1 affects many different processes in HD neurons to gain an understanding of how we can use the system to develop new treatments for HD.

Depending on the formulation, treatment can cause skin irritation, breast enlargement and tenderness, sleep apnea, acne, reduced sperm count, increased red blood cell count, and other side effects.

Some examples of the effects of the herbal tinctures are, protection of the immune system, to help combat the effects of stress, improved memory, learning, and reaction time, reduction of anxiety and depression (without causing drowsiness), stabilizing blood sugars, lowering cholesterol, reducing brain - cell degeneration, and aiding in treatment of inflammation.

1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones andreduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones andReduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones and teeth

● Protect cells, slow tumor growth and reduce side effects of chemotherapy treatment in cancer patients.

It is a non-invasive fat removal and fat elimination treatment which utilises safe radiofrequency (RF) technology to help reduce unwanted fat cells.

Topical treatments are claimed to reduce oil production, increase skin cell turnover, and kill off bacteria, which in combination supposedly reduce inflammation.

Topical Retinoids This topical treatment for acne works by reducing * the skin's natural production of sebum while at the same time preventing dead skin cells from clogging hair follicles.

The goals of naturopathic allergy treatment includes 1) identifying the allergens and reducing or eliminating your exposure to them, 2) decreasing your immune system's sensitivity to these allergens, 3) stabilizing your mast cells to decrease the release of excess histamine, 4) reducing discomfort from current allergy symptoms.

Laser is used for the treatment of all kinds of musculoskeletal injuries to help reduce pain, muscle spasm, inflammation and encourage cell reproduction.

The clove treatment was found to significantly reduce hepatic cell proliferation and processes involved in liver cirrhosis.

Intensive Resurfacing Peel with Durian Cell Reform This is said to be an intensive exfoliating anti-aging treatment to reduce the appearance of fine lines and wrinkles.

As if that result isn't enough, the inclusion of Apricot Stem Cells adds a powerful anti-inflammatory and soothing benefit to the resurfacing treatment by helping to reduce redness, promote an even tone and boost skin tolerance.

These state - of - the - art treatments assist with inflammation, pain, tissue repair, cell growth, vascular activity, increased metabolic activity, trigger points and acupuncture points, in addition to reducing the appearance of scar tissue, improving nerve function, and enhancing wound healing.