Not exact matches
These young people had failed to achieved remission
using other
treatments, including stem
cell transfers, so this approval may be life - saving.
The company has been trying to win FDA approval for Opdivo to be
used as a first option
treatment for non-small
cell lung cancer (NSCLC).
Gilead subsidiary Kite Pharma (which the biotech giant scooped up ahead of the FDA's approval for Yescarta, a
treatment that reengineers patients» immune
cells to fight cancer) will have access to Sangamo's platform technology, which could be
used to create various types of cancer
cell therapies.
Cancer immunotherapies, or
treatments that
use the body's immune system to fight cancerous
cells, were once again the most hotly anticipated drug class at the conference.
CAR - T
cell therapy is a form of immunotherapy, a rapidly developing cancer
treatment that
uses patients» own immune
cells to attack tumors.
Researchers from Osaka University, in collaboration with the Max Planck Institute for Polymer Research, recently found a way to produce polymer solar
cells without the need for these specialized
treatments, while improving its conductivity, by
using amorphous polymer blends and adding a component.
«We remain committed to developing better
treatments for patients battling ALL and believe an approach
using our defined
cell technology is the best platform to pursue,» Bishop added.
In 2014, the company raised $ 304 million to fund its experimental cancer
treatments that
use a person's own immune
cells.
Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test
using Epic Sciences» non-EPCAM-based circulating tumor
cell detection platform, which could help guide
treatment decisions for men with metastatic castration - resistant prostate cancer.
Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer
cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the
treatment of ocular melanoma, a rare and life - threatening disease.
This includes a stem
cell research centre, a network of drug discovery institutes and a # 20 million global clinical development fund dedicated to supporting Phase I and II clinical trials; and a # 2 million collaboration between University of Cambridge and University College London that will
use donated
cells from people with Alzheimer's to test potential new
treatments
The difficulties associated with obtaining nerve tissue at the correct stage of development and differentiation from aborted embryos means that foetal tissue transplantation is no longer in favour, but the creation of human embryos specifically as sources of stem
cells, and the push to
use «spare» embryos from IVF
treatments is gatheringmomentum.
Much more needs to be done to alert the public to the
treatment successes obtained through the
use of adult stem -
cell research.
Cord blood stem
cells are also often a better option for medical
treatments than bone marrow, another option often
used in stem
cell therapies.
If your twins are fraternal, it is also good to know that most current cord blood
treatments require the
use of a well matched donor's stem
cells, like a sibling's.
Treatment typically involves chemotherapy (
using chemicals intravenously to kill cancer
cells), radiation therapy (
using high - powered X-rays to kill cancer
cells), or surgery to remove the breast and surrounding lymph nodes.
Of the preparations available for
treatment of allergic symptoms, corticosteroid nasal sprays (e.g., Flonase, Nasacort, etc.) and cromolyn sodium nasal spray (a mast
cell stabilizer, e.g., Nasalcrom) are considered to be, by far, some of the most effective and safest to
use in breastfeeding moms.
Fat - derived stem
cells can heal nasty wounds associated with Crohn's disease, and could be the first mass stem
cell treatment to be
used in Europe
The new
treatments, called CAR T
cell therapies, eliminate cancer
using people's own
cells.
The
treatment, called CAR - T immunotherapy,
uses genetically engineered T
cells, immune system fighters usually tasked with identifying invaders in the body,...
Trials of
cells made from human embryonic stem
cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem
cells have been
used in the
treatment of major lethal diseases.
«
Used in cancer therapy, this process could increase the impact of a
treatment by heating the cancer
cells while introducing the drug compound into the tumor.»
Identifying how
cells respond to their surrounding environment is important information that can be
used to help guide
treatment decisions for patients.»
Inspired by his own bout of leukemia to try to find a better cancer
treatment, retired broadcasting station owner Kanzius guessed that as an alternative to chemotherapy, he could inject tumors with metal ions, then
use radio waves to heat the metal and destroy cancerous
cells.
Similar approaches
using killer T
cells are already being investigated as a cancer
treatment, with some promising results.
As a result, P - gp causes resistance of the diseased
cells to a majority of drugs currently available for the
treatment of cancer, as well as drugs
used for
treatment of infectious diseases like HIV / AIDS.
Nor do they need to be nourished from underneath by «feeder layers» of animal
cells which have been shown to contaminate human
cells grown, making them unsuitable for
use in medical
treatments.
Figure on the left: Analyzing the relative sensitivity of hundreds of cancer
cell lines to commonly
used anti-cancer drugs (each dot) reveals that
cells with suppressed expression of one proteasome cap subunit are specifically resistant to
treatments with the proteasome inhibitors MG132 and bortezomib.
But the neurosurgeon who fused Boesen's neck bones to stabilize his spine offered a ray of hope: Boesen might qualify for an experimental
treatment that
uses stem
cells to repair damaged tissue.
A «Trojan horse»
treatment for an aggressive form of brain cancer, which involves
using tiny nanoparticles of gold to kill tumour
cells, has been successfully tested by scientists.
Teams conducting research into
treatment methods for various chronically inflammatory autoimmune diseases are already
using the link between IL - 6 and pathogenic T
cells today.
But Christopher Centeno, Regenerative Sciences» medical director, argues that as the
treatment uses a patient's own stem
cells, it is a medical procedure akin to in vitro fertilization, and therefore none of the FDA's business.
June is also a scientific adviser on a planned US trial that would also
use CRISPR — Cas9 - modified
cells for the
treatment of cancer.
For now, the
treatments are approved for
use only when other
treatments have failed, but someday CAR - T
cell therapy could be the first
treatment doctors try, he says.
The exciting implication is that next - generation wastewater
treatment plants could
use new technologies, including microbe - powered fuel
cells, to capture enough methane, hydrogen, and other fuels from wastewater to generate all the energy they need, and then some.
BABY BLUE
Using human eye
cells, researchers fashioned an artificial eye surface that could be
used to study and test
treatments for eye diseases.
These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and advances in the
use of gene therapy, despite some setbacks; continuing progress in research on stem
cells; the emergence of
treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.
The team believes that whichever way BMP - 7 is
used, it will be less risky than other
treatments for type 1 diabetes that are currently being investigated, such as those that create pancreatic
cells from stem
cells, or by introducing new genes into the body.
The researchers concluded that if vitamin D is to be
used in patients with rheumatoid arthritis, clinicians may need to prescribe much higher doses than currently employed or provide a
treatment that also corrects the vitamin D insensitivity of immune
cells within the joint.
Treatment for advanced melanoma has seen success with targeted therapies — drugs that interfere with division and growth of cancer
cells by targeting key molecules — especially when multiple drugs are
used in combination.
An attempt by the Chinese health ministry to enforce a ban on the clinical
use of unapproved stem -
cell treatments has had little effect
Bioengineers from Queen Mary University of London (QMUL) have shown for the first time that lithium chloride, a common drug
used to treat mental health disorders, could offer an effective
treatment against osteoarthritis by disrupting the length of the
cells» antennae called primary cilia.
«With the rise of new and unproven stem
cell treatments, the NFL faces a daunting task of trying to better understand and regulate the
use of these therapies in order to protect the health of its players,» said Kirstin Matthews, the Baker Institute fellow in science and technology policy and an expert on ethical and policy issues related to biomedical research and development.
Despite a lack of rigorous clinical trials to test safety or efficacy, a ban of the
treatment by health authorities, and a lack of peer review by the scientific community, the privately funded Stamina Foundation has been
using cultured mesenchymal stem
cells that have been exposed to putative conditions that favour neuronal differentiation to treat different diseases in severely or terminally ill patients.
«We believe that the sensitivity to antibodies
used as potential HIV
treatment and to certain antiretroviral drugs can be decreased by
cell - to -
cell transmission.
To
use these
cells to develop new
treatments for MS, Zack is working with Peter Calabresi, M.D., professor of neurology and director of the Johns Hopkins Multiple Sclerosis Center.
«There is still a lot of work to be done before this approach might be
used in the clinic, but we're hopeful that it will pave the way for new kinds of
treatment for patients with sickle
cell disease.»
Saatchi, which is owned by France's Publicis Groupe, SA, chose LifeStraw over a field of competitors that included a reusable controller to improve the distribution of IV fluids, a collapsible wheel that can be folded down for easier storage when not in
use on bicycles or wheelchairs, an energy - efficient laptop designed for children in developing countries, a 3 - D display that
uses special optics and software to project a hologramlike image of patient anatomy for cancer
treatment, an inkjet printing system for fabricating tissue scaffolds on which
cells can be grown, a visual prosthesis for bypassing a diseased or damaged eye and sending signals directly to the brain, books with embedded sound tracks to help educate illiterate adults on health issues, a phone that provides telecommunications coverage to poor rural populations in developing countries, and a brain - computer interface designed to help paralyzed people communicate via neural signals.
Exploiting the same pre-clinical model
used for their studies, the researchers are testing the efficacy of this kind of drug candidates against cancer stem
cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the
treatment of human breast cancer.
In the current study, the researchers took diaphragm tissue from donor rats and removed all the living
cells from it
using a series of chemical
treatments.