Sentences with phrase «cell treatments based»

«Irrational and unverified stem cell treatments based on methods that are not validated or scientifically documented should not reach patients.

Not exact matches

A particularly effective treatment against many cancers, platinum - based chemotherapy, has the unfortunate side effect of damaging the hair cells in the ear that are responsible for sensing sound waves, Goldrich said.

Current treatments are based on the bulk, brute removal of cells — but miss even a few, and evolution will see to it that the cancer returns in a new, often more resistant, form.

Based on the evolutionary idea that targeted epigenetic stochasticity can improve adaptation, these observations could explain how cancer cells are good at evading chemotherapy treatments and spreading from one part of the body to another, he adds.

To make stem cells the basis for safe medical treatments, however, the field would need the ability to tightly control stem cell pluripotency, the ability to become many cell types, and self - renewal or immortality, the ability to keep dividing and multiplying over time in constant turnover.

[Praveen R. Arany et al, Photoactivation of Endogenous Latent Transforming Growth Factor — β1 Directs Dental Stem Cell Differentiation for Regeneration] Could a light - based treatment for cavities and chipped teeth eventually be in the offing for people?

Finally, we are in a winning position in the war against cancer thanks to new treatments based on modified immune cells

This is how treatments based on a type of white blood cell called T - cells are curing some cancers, rather than just slowing their advance (see «Cancer meets its nemesis in reprogrammed blood cells «-RRB-.

The new recommendations will likely result in more patients worldwide obtaining treatment, based on their CD4 immune cells counts.

There are no current treatments for HD, although Thompson's ongoing work with stem cell - based therapies are showing promise.

The researchers hope that ultimately human trials will prove the efficacy of the OH14 compound in sensitising tumour cells and cancer stem cells to existing drug - based therapies thus disabling tumours from seeding new growth after treatment.

What's more, the studies suggest how our gut microbes make the immune system turn against nerve cells — a finding that could lead to treatments, like drugs based on microbial byproducts, that might improve the course of the disease.

An extended transplant window could make time for drug or stem - cell based treatments — even gene therapy.

A woman in Japan has received the first medical treatment based on induced pluripotent stem cells, eight years after they were discovered.

Research based on such false cell lines would undermine the understanding of different cancers and possible treatments, and clutter the scientific literature with bogus conclusions.

But where atomic research had a single, explosive debut, gene - and cell - based treatments have emerged in fits, after many false starts.

Geoffrey Raisman, who is developing treatments based on OECs at the Institute of Neurology in London, says the work could lead to a better source of the cells.

Since iPS cells can be made from adult tissue samples, the technique does not require the destruction of embryos, unlike stem - cell - based AMD treatments that are also being worked on.

Still, a few stem cell therapies have now been approved, such as a treatment available in India that takes stem cells from the patient's eye in order to regrow the surface of their cornea, and a US product based on other people's bone stem cells.

Israel - based company, Emefcy, named as a play on the acronym for microbial fuel cell (MFC), starts with the same principle as most wastewater treatment — water is aerated so bacteria in the liquid break down organic material in a closed series of containers known as a bioreactor.

In addition to providing insights regarding selection of treatment, this blood test may also prove helpful in assessing the presence of residual disease, recurrence, or relapse and detection of therapy - resistant cancer cells more quickly than conventional tissue - based methods.

«It is our hope that the results of this study provide a footing for further advancement of personalized, cell - based treatments for currently incurable and devastating neurological disorders.»

Dr Leonardo Guasti added: «It represents an entirely new concept for the study of the adrenal gland as the ability to generate donor - specific and functional adrenal - like cells will facilitate the next generation of cell - based treatments for adrenal insufficiency, the modelling of adrenal specific diseases, and the testing of personalised interventions on cells derived from patients.»

Of the stem cell procedures that are marketed, 61 % of businesses offer fat - derived stem cell interventions and 48 % offer bone - marrow - based treatments.

We have found that exosomes and the cargo they contain are crucial mediators of stem cell - based heart regeneration, and we believe this might lead to an even more refined therapy using the «active ingredient» instead of the entire stem cell,» said Eduardo Marbán, MD, PhD, director of the Cedars - Sinai Heart Institute and a pioneer in developing investigational cardiac stem cell treatments.

Today the brain's serotonin system is already a known target for the treatment of depression, and according to researchers it should be possible to use time signals in pharmaceutical development based on stem cells.

Nevertheless, he thinks this sort of technology will be seen in the clinic before a treatment based on a stem cell replacement for photoreceptors.

Researchers, physicians and patients need T cell - based products that can respond to malignant or infected cells that may reappear months or years after treatment.

The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.

The treatment is based on making bone marrow cells express the telomerase enzyme, which is responsible for repairing telomeres.

Peter Aldhous's article discusses US restrictions on patients being given treatments based on their own stem cells (10 August, p...

Cancer chronotherapy is based on the concept that the right time of treatment during the day could decrease side effects to normal cells while killing cancer cells.

Building on Brown's amazing recovery but hoping to avoid the pitfalls, AIDS researchers are devising treatments based on the patient's own tissue, which would not be subject to rejection like donor cells.

By doing this, we increased the efficacy of the treatment and we believe that in turn the treatment targeted the stem cells, which are the basis of recurrence.

Researchers also monitored prostate cancer risk, based on prostate - specific antigen levels and a rectal exam, and stroke risk, based on red blood cell levels during the treatment year and for at least a year afterward.

The researchers, who are based at the Academy of Scientific & Innovative Research, located at the CSIR - Indian Institute of Chemical Technology, Hyderabad, India, hope that the technique can enhance regenerative therapy for conditions like chronic wounds, where harsh inflammation in the wound can kill the cells used in regenerative stem cell treatments.

They have enormous clinical potential; unlike stem cells isolated from adult tissue that have been the basis of stem cell treatments so far, hESCs can be grown into any of the body's 200 tissue types.

«But, based on our data, we believe there is a case for early intervention with personalized antiviral treatments following stem cell transplantation in order to suppress hCMV reactivation.»

But doubling the number of RNA guides adds bulk, which could make it harder to deliver a CRISPR - based treatment into cells.

One of those treatments might someday be based on a synthetic protein fragment that Robert P. Hammer of Louisiana State University has developed to disrupt formation of the plaques believed to provoke massive brain cell death in Alzheimer's patients.

Sex - based distinctions at the level of the cell may not only influence cancer risk but also the effectiveness of treatments.»

Abnormal levels of the proteins may be useful biomarkers that could help us study early treatments to limit or reverse the damage to brain cells and even prevent the development of the full - blown disease,» said study author Edward Goetzl, MD, a Professor of Medicine with the University of California, San Francisco, a researcher at the National Institute on Aging, and a scientist of NanoSomiX, Inc., a California - based biotechnology company that provided a grant for method development for the study.

Cancers would be caught at their earliest stage and other stages of development, and doctors would have the necessary protein or genetic information from these captured cells to customize your treatment based on the specific markers for your cancer.

While thousands of agents based on camptothecin have been synthesized, and two of these analogs — irinotecan and topotecan — have been approved for treatment of many solid - tumor cancers, these compounds typically are highly toxic to healthy cells, and not all of them have proven effective as anticancer agents.

Professor Steven Bova, based at the University of Tampere, Finland, and head of ICGC prostate cancer UK metastatic studies, said: «The diversity we've found suggests multiple biopsies might be needed to identify the «trunk» of the cancer's tree of mutations — we need treatments that target these core weaknesses to destroy all cancer cells in a clean sweep, rather than trimming the branches.

A trial in 18 people with damaged retinal cells is being hailed as the most promising yet for a treatment based on human embryonic stem cells (hESCs).

The so - called Stamina method is a treatment based on bone marrow stem cells that Stamina's President Davide Vannoni claims can grow new neurons under specific conditions and hence cure several neurodegenerative diseases.

«Based on the results seen with ADRCs in the PRECISE trial, we designed ATHENA to look at these cells as a possible treatment option for people with refractory chronic myocardial ischemia.»

The ability to create sensory interneurons with a patient's own reprogrammed cells holds significant potential for the creation of a cell - based treatment that restores the sense of touch without immune suppression.

«Stem - cell - based therapy promising for treatment of breast cancer metastases in the brain.»