Until such time, people investigating stem
cell treatments need to be aware of what is and isn't regulated in the countries in which they seek treatment.
Not exact matches
Making personalized, or «autologous» stem -
cell treatments, can make the process go a lot faster, since a person's
cells don't
need to be shipped out, reprogrammed, then reinserted into the body.
Researchers from Osaka University, in collaboration with the Max Planck Institute for Polymer Research, recently found a way to produce polymer solar
cells without the
need for these specialized
treatments, while improving its conductivity, by using amorphous polymer blends and adding a component.
Much more
needs to be done to alert the public to the
treatment successes obtained through the use of adult stem -
cell research.
Phytic acid's chelating effect may serve to prevent, inhibit, or even cure some cancers by depriving those
cells of the minerals (especially iron) they
need to reproduce.17 The deprivation of essential minerals like iron would, much like other broad
treatments for cancer, also have negative effects on non-cancerous
cells.
Usually, no
treatment is
needed — avoiding the triggers is normally enough to prevent a crisis, or removing them is all that's necessary to eliminate symptoms, because the body then starts to create new red blood
cells naturally.
A 50,000 unit blood bank would provide economies of scale that would reduce the cost to the NHS for every
treatment as well as radically reducing the
need to import stem
cell units from abroad, which is a common and expensive practice today.
On this edition of
Need to Know — the fight to survive, to improve
treatment, to raise funding and to educate - all in the name of sickle
cell.
For a cancer with very high genetic diversity (like AML) however, the unintended effect of
treatment is often to select for the most aggressive, resistant
cells, clearing away their competitors and furnishing them with all the resources they
need to flourish.
To make stem
cells the basis for safe medical
treatments, however, the field would
need the ability to tightly control stem
cell pluripotency, the ability to become many
cell types, and self - renewal or immortality, the ability to keep dividing and multiplying over time in constant turnover.
Nor do they
need to be nourished from underneath by «feeder layers» of animal
cells which have been shown to contaminate human
cells grown, making them unsuitable for use in medical
treatments.
It provides a home for donor
cells to grow and proliferate, bypassing the
need for any drug and radiation
treatment.
Because the CAR - T
cells do not eradicate all cancer
cells, the researchers think the immune therapy will
need to be combined with other
treatments.
The exciting implication is that next - generation wastewater
treatment plants could use new technologies, including microbe - powered fuel
cells, to capture enough methane, hydrogen, and other fuels from wastewater to generate all the energy they
need, and then some.
He
needed a stem
cell transplant, which is a normal
treatment for leukemia, but his cancer
needed to be in remission first, and the chemotherapy wasn't working.
The finding identifies how vulnerable
cell groups react and respond differently to the accumulation of mitochondrial DNA damage seen in the disease, highlighting the
need for
cell - specific
treatments.
The researchers concluded that if vitamin D is to be used in patients with rheumatoid arthritis, clinicians may
need to prescribe much higher doses than currently employed or provide a
treatment that also corrects the vitamin D insensitivity of immune
cells within the joint.
Yamanaka's technique may enable doctors to grow stem
cells from adult
cells of patients
needing treatment.
The glue could also help to deliver drugs to the exact
cells that
need them, avoiding nasty side effects from less targeted
treatments such as chemotherapy.
Scientists are hopeful that ultimately these
cells could be transformed in the laboratory to yield specific
cell types
needed for a particular
treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.
«Stem
cells may offer unprecedented opportunities to develop
treatments for many diseases with unmet medical
needs.
People with type 1 diabetes
need lifelong
treatment with insulin, which helps transport the sugar glucose from the bloodstream into
cells, where it serves as a key energy source.
While further research is
needed to achieve these goals, the current approach can already help to characterize and assess
treatments aimed at inhibiting influenza entry into
cells.
If tumor
cells are present within the node, the primary tumor has spread and additional lymph nodes may
need to be removed and medical
treatments tailored accordingly.
Researchers, physicians and patients
need T
cell - based products that can respond to malignant or infected
cells that may reappear months or years after
treatment.
New preclinical research on the molecular mechanisms responsible for sickle
cell disease could aid efforts to develop much
needed treatments for this devastating blood disorder that affects millions worldwide.
«We still
need more studies to determine if there are other
treatments that can be used to slow the progression of kidney disease specifically in individuals with sickle
cell trait.»
Chien agrees that basic stem
cell biology has not kept pace with clinical studies, but he says there is a compelling
need for new
treatments.
One fundamental goal of diabetes
treatment is to preserve and restore functional beta
cells, thereby replenishing levels of a hormone called insulin, which moves blood glucose into
cells to fuel their energy
needs.
«Genes
need to be screened for stem
cell transplants: Findings underscore
need for screening methods to improve safety of promising experimental
treatments.»
Conventional
treatments for diseases such as cancer can carry harmful side effects — and the primary reason is that such
treatments are not targeted specifically to the
cells of the body where they're
needed.
«I think what's
needed for collective invasion will depend on the environmental stresses the cancer
cells face, and it may shift with
treatment,» Marcus says.
Commenting on Tong Yuan's
treatment for Parkinson's disease, Oliver Cooper, director of the Stem
Cell Facility of the Neuroregeneration Institute at McLean Hospital in Belmont, Massachusetts, and a specialist in Parkinson's disease, says, «The products offered by Tong Yuan may provide anecdotal, poorly controlled, transient improvements in the patients, but Parkinson's - disease patients
need long - term therapies.»
Lacking the expensive machinery
needed to validate
cell lines on their own, most researchers either skip validation or ship their cultures to specialized labs which can delay important findings and
treatments.
Researchers reporting online February 13 in the
Cell Press journal
Cell Stem
Cell recently found a way to create platelets without the
need for donated blood, an advance that could possibly erase supply shortages and ensure platelet
treatments for all who
need them.
A trained robotic surgeon experienced in the
treatment of prostate, bladder and kidney cancer, Assoc Prof Chia said, «For anticancer drugs to achieve their best effectiveness, they
need to penetrate into the tumour efficiently in order to reach the cystoplasm of all the cancer
cells that are being targeted without affecting the normal
cells.
The possible use of stem
cell therapy for
treatment of Parkinson's disease is long awaited and much
needed (2 December,...
To develop new, targeted
treatments to eliminate these residual infected
cells, we
need to find exactly where in the CD4 T lymphocyte population the virus hides.
Professor Steven Bova, based at the University of Tampere, Finland, and head of ICGC prostate cancer UK metastatic studies, said: «The diversity we've found suggests multiple biopsies might be
needed to identify the «trunk» of the cancer's tree of mutations — we
need treatments that target these core weaknesses to destroy all cancer
cells in a clean sweep, rather than trimming the branches.
More work is
needed to verify that the
treatment is broadly successful in all CLL patients and that stray cancer
cells don't eventually mutate so that they avoid displaying the molecule targeted by the T
cells.
Therapeutic applications of CRISPR - Cas gene editing are being advanced with the goals of finding cures and
treatments for a range of serious diseases, developing
needed medicines for both household pets and production animals, and improving
cell culture systems for bioproduction.
(To be sure, these people would often
need to get such
treatments early, before their conditions progressed and too many brain
cells died.)
The
treatment is currently being tested on other
cells and
needs to be tested in live models before we can think about experimental clinical trials.
\ n \ nI am very concerned because my Grandson has Spinal Muscular Atrophy and he
needs the embryonic stem
cell treatment to survive, before he dies.
More work will
need to go into making sure any
treatment based on this technique will only target cancerous
cells and not healthy ones.
Although autologous
cell transplantation circumvents the
need for immunosuppressive
treatment, it is not always available or most effective.
Recognizing there is still a tremendous
need for better diabetes
treatments, ViaCyte remains dedicated to developing
cell replacement technologies as a way to significantly improve patients» lives.»
Scientists developing new
cell therapy methods for the
treatment of disorders such as sickle
cell disease or leukemia
need to consider how their culture conditions may affect the success of their translational research.
«Well, we know that these basal breast cancer
cells are very plastic and we
need to incorporate that kind of thinking into
treatment regimes,» says Chaffer.
The authors say that it's possible that the new trabecular meshwork
cells generated from the stem
cell treatment could eventually succumb to the same mechanisms that caused the fluid buildup in the first place, but further research is
needed in that area.