Sentences with phrase «cell tumors tend»

Mast cell tumors tend to be particularly aggressive in the Shar - Pei and can spread to lymph nodes and other organs.

Not exact matches

According to this theory, tumor cells tend to «forget» the tissue from which they originated as the disease progresses, acquiring an undifferentiated phenotype associated with heightened aggressiveness and treatment resistance.

Proliferation of such cells, which tend to resist chemotherapy and help tumors spread, are considered a major roadblock to successful cancer treatment.

When the protein is present, these cells that start out round and stuck together in a pattern resembling cobblestones become irregularly shaped and tend to detach from the tumor site in an uncoordinated way — hallmarks of metastasis.

As early as 1978 Alberto Mantovani of Humanitas Clinical Institute and the University of Milan had observed that innate immune cells tend to congregate around some tumors.

Because diseases such as cancer tend to evade detection by T - cells» receptors, allowing a tumor to grow unchecked, scientists have long sought «intel» on this process as a means of developing therapies that target malignant cells, but leave healthy cells alone.

Singlet oxygen tends to rip apart tumor cells in a manner that exposes many new tumor antigens to immune cells called dendritic cells, which, like police executing a dragnet, grab the antigens and present them to T cells for closer inspection.

A possible explanation may be that, according to prior research findings, tumors of the lung and bowel tend to be colonized by particularly high quantities of immune cells.

And because tumors typically have a leaky, ill - formed vasculature, the particles tend to leak out at the site of cancer tissue and be picked up and internalized inside tumor cells.

«Tumors whose cells tend to be highly mutated, like those of melanoma and lung cancer, are the ones that respond best to immunotherapies,» says Harari.

Tumors with high levels of E-cadherin tend to be tightly tethered to nearby cells and less likely to break free and travel to other sites.

«The idea is that tumors that have a lot of mutations are more immunogenic so that is why they tend to be infiltrated by T cells,» Celis says.

One found that people who had more T cells in their tumors before the treatment began tended to fare better.

Bernese Mountain dogs tend to contract lymphoma, mast cell tumors and histiocytosis, a rare cancer, which oncologists treat with chemotherapy and radiation.

Mast cell tumors, as with many other forms of cancer, tend to be associated with age.

Cells that are undergoing frequent cell divisions (multiplying) are the most sensitive to radiation and this is why tumor cells tend to be more susceptCells that are undergoing frequent cell divisions (multiplying) are the most sensitive to radiation and this is why tumor cells tend to be more susceptcells tend to be more susceptible.

That said, Siamese cats do tend to be unusually prone to cancer, most commonly lymphoma, mast cell tumors and mammary tumors.

Due to their cell of origin, they tend to arise within the ventricular system and can block drainage of CSF, thus a small tumor can cause very severe neurologic signs.