Sentences with phrase «cell types of interest»

We additionally established differentiation protocols for all neuronal cell types of interest.

Current efforts, mostly conducted in animal models, involve attempting to derive and aggregate embryonic stem cells, exposing them to such factors as acetic acid, allowing them to differentiate, or specialize, and then sorting through these cells to extract the cell types of interest.

This corrected clonal cell line can also be differentiated into the cell type of interest.

We have recently developed the use of site - specific nucleases to genetically engineer human pluripotent stem cells, which can be maintained indefinitely and differentiated into any cell type of interest.

Choose the right format of gene editing tool and delivery reagent for your cell type of interest

Not exact matches

Embryonic stem cells are scientifically and medically interesting because they are «pluripotent» (capable of generating many cell types), but they are not the same as totipotent single - cell embryos.

This sparked my interest in the role of one type of immune cell — dendritic cells — in GVHD, and I thought this could constitute a postdoc project.

«The challenge has been how to direct certain therapies designed to manipulate genes of interest in specific cells without developing a specific drug carrier for each specific cell type.

«All of them are interesting; all of them are important,» Collins said about the three types of stem cells.

Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem cells and [the] like, it may be interesting to see if there are other ways, alternatives to dealing with really badly damaged hearts that would involve growing a new heart or replacing or repairing the damage d to a badly damaged heart that might make artificial hearts less important in the somewhat more distant future.

Cancer stem cells, a type of self - renewing cell found in tumors, are of particular interest because they are the main cell type responsible for tumor progression and for resistance to chemotherapy and radiotherapy, and therefore a major cause of tumor recurrence after treatment.

To visualize different cell types in the brain, researchers often need genetic access to that cell — the ability to express a gene of interest only in, say, chandelier cells, but not neighboring neurons.

These cells can develop into all the body's cell types and are therefore of considerable interest to the field of regenerative and reparative medicine.

«We're interested in learning more about what other proteins LRP6 interacts with, as well as how it acts in different types of brain cells at different developmental stages of circuit development and refinement.»

The observation of a cut - off point at which the progenitor cells can not make some neuron types extends «a word of caution for people interested in using stem cells» to resolve neurological problems, says neuroscientist Paula Monaghan of University of Pittsburgh in Pennsylvania.

«We were interested in the origins of lamprey gut neurons because in other vertebrates they arise from a particular embryonic cell type, called neural crest cells,» says Stephen Green, postdoctoral scholar in biology and biological engineering and co-first author on the paper.

They're also interested in exploring the effect of other types of infertility - associated mutations on germ cell production.

A well - defined cell type that has been widely used to identify the consequences of ablation or ectopic expression of a gene of interest.

Tseng Laboratory scientists are interested in learning more about the function of human brown fat cells, including whether humans have two types of BAT, and understanding how BMP and related factors affect human brown fat production.

The things that we have demonstrated — such as the fact that the vertical nanowires can deliver any biological effector to any cell type in a spatially selected fashion — have drawn interest from many different people, and we have been working with stem cell institutes and others to demonstrate the unique utility of this particular platform.

By expressing foreign genes in target cell types, they hope to be able to specifically silence or activate cells of interest.

It is interesting to note that p21 - deficient mice did not develop T - cell lymphomas, which is one of the most common tumor types in p53 - null and p19ARF - null mice (36, 37, 38, 42, 43).

However, the ways in which the different types of stem cells came to be accepted into the stem cell family is itself an interesting story, and one that can help paint a useful bigger picture, and that is why this story will be the focus for this blog post to celebrate International Stem Cell Awareness cell family is itself an interesting story, and one that can help paint a useful bigger picture, and that is why this story will be the focus for this blog post to celebrate International Stem Cell Awareness Cell Awareness Day.

«These are interesting results proving it is theoretically possible to «regress» cells back to an earlier stage in development when they are self - perpetuating and still have the potential to be directed to become a whole range of different cell types, whether nerve cells, heart muscle or bone.

The most interesting aspect of the study, say the authors, is the discovery of a new, specialized function of a certain type of regulatory T cell, which is to enable microbes to play useful roles by keeping them from causing inflammation.

However, the ways in which the different types of stem cells came to be accepted into the stem cell family is itself an interesting story, and one that can help paint a useful bigger picture.

In laboratory experiments on mice modified to mimic the signs of MS, the team employed an Activatable Cell - Penetrating Peptide (ACPP), a special type of molecular probe that delivers fluorescent agents to a region of interest.

Research Interests: Molecular control of cell fate from stemness to differentiated skeletal and neuronal cell types; SOX transcription factors; skeletal malformation and degeneration diseases; intellectual disability and autism spectrum disorders; mouse genetic models; human pluripotent stem cell differentiation models in vitro

The cardiomyocyte [heart muscle cell] is one cell type I've had an interest in for a while, and it's what most of my background and training has been in.

In each case there is interest in obtaining comprehensive, accurate data for particular cell types and in identifying patterns of variation within the data.

It is interesting to note that when comparing these gene expression changes between ER - α - positive and negative lines, very little correlation was seen between the cell types, which is supportive of previously published data (36).

While there's growing interest in the use of stem cell transplantation for treating type 2 diabetes, not much research has looked at the use of stem cells derived from bone marrow.

With bitters, digestive enzyme secretions are increased, helping to promote the complete breakdown of nutrients into their absorbable units, preventing gas formation when large molecules are acted upon by bacteria further down the small intestine.2, 11 The complete breakdown of proteins is particularly important, as the cross reactivity of immune cells between undigested protein molecules and intestinal cells plays an important role in the etiology of conditions such as celiac disease.15 Insulin and glucagon secretions are stimulated, helping to stabilize blood sugar levels.3, 11 Many bitters formulations have been traditionally used in the treatment of type 2 diabetes, and it is interesting to point out that many naturally sweet substances are often paired with some bitterness in nature.4, 11 Herbalist Jim McDonald hypothesizes that our cravings for sweetness may mask cravings for bitterness for this reason.4

Dr. Rankin enjoys many aspects of oncology, and has a special interest in electrochemotherapy to treat various tumor types (including sarcomas, melanomas, mast cell tumors, oral tumors, and more).

What's interesting to me is that the survey, which is carried out for the various phone companies in Canada, measured land line only, cell phone only, but not cable of VOIP only, reporting instead on the aggregate cable or VOIP use with and without the use of other phone types.