Not exact matches
Food Allergy Center research investigator and lead author of the study Jessica O'Konek said: «We're
changing the way the immune
cells respond
upon exposure to allergens.
Using
cell models and genetically engineered mice, the authors then could reproduce kidney disease
changes upon expression of APOL1 gene variants, but the disease required the presence suPAR.
The current research findings build
upon recent discoveries including novel identification of key genetic
changes in
cells of the immune system.
If the
cells reduce the copy number of this specific chromosome again — say
upon another
change in environmental conditions — then they turn back into a smooth colony.
We hypothesize that
upon retinal neuronal damage MG or RPE
cells undergo defined and controlled
changes in cellular and molecular phenotype towards a
cell with progenitor properties — this process that we are studying we call regenerative reprogramming.
Upon T
cell receptor signaling, these
cells initiate a differentiation program that includes complex
changes in CD4 and CD8 expression, allowing identification of transitional intermediates in this developmental pathway.
Mitotic position and morphology of committed precursor
cells in the zebrafish retina adapt to architectural
changes upon tissue maturation.
Within this ecosystem, innate and adaptive immune
cells maintain and protect tissue function, integrity, and homeostasis
upon changes in functional demands and diverse insults.
Overall, these results indicate that
changes in ATP levels are a reliable indicator of
cell death in stem
cell populations
upon drug insults and may have utility for hESC - based automatic screening assays.
Following CNS damage, microglia
change from a surveillant to a reactive state, displaying alterations in
cell morphology and phenotypes that vary based
upon the type and extent of (insulting) stimulus to which they are exposed and respond.
Those constituents are being acted
upon by the same gravitational «force» acting on the
cell, and the work they do is going to cancel any
change in overall energy due to gravitation other than that due to the tidal forces.