Sentences with phrase «cell viability shown»

Not exact matches

Researchers at Texas Woman's University have shown that a diterpene geranylgeraniol found in linseed oil, Cedrela toona wood oil, sucupira branca fruit oil and more recently, annatto seed oil, suppressed the viability of human DU145 prostate carcinoma cells via cell cycle arrest at the G1 phase and the initiation of apoptosis.

The cells showed good viability and demonstrated spreading and other phenotypic behavior consistent with cells interacting with collagen hydrogel scaffolds.

However, when ALCL cells were treated with 1 μmol / L doxorubicin and increasing concentrations of rapamycin, cell viability was lower compared with treatment with rapamycin alone (data not shown).

(B) Shown is a representative plot of viability eFluor780 stained samples (left) and the percentage of live cells (mean ± SD, right) of a single representative experiment, shown in Fig 1D of 3 independent experimShown is a representative plot of viability eFluor780 stained samples (left) and the percentage of live cells (mean ± SD, right) of a single representative experiment, shown in Fig 1D of 3 independent experimshown in Fig 1D of 3 independent experiments.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

Moreover, annexin V / propidium iodide staining showed that VPA only marginally decreased the viability of in vitro — differentiated Th1 and Th17 cells at a relatively high concentration (1 mM)(Supplemental Fig. 4A, 4B), whereas VPA readily inhibited the differentiation of Th1 and Th17 cells at a low concentration (0.2 — 0.5 mM), indicating that apoptosis induction was not the primary mechanism for Th1 and Th17 cell differentiation inhibition (28, 29).

The kahweol concentrations required to inhibit the differentiation of HUVEC cells did not affect their viability (results not shown).

The viability of each individual cell was monitored by measuring the level of fluorescence of specific vital dyes that leak out from the damaged cell (PNB - induced cell damage was shown to have a disruptive mechanical nature [40,45,47]-RRB-.

RPE cells derived from HESC show long - term viability in vivo, since in a previous study we have shown that HESC - derived RPE can survive in the RCS subretinal space for up to 10 weeks [9], whilst a recent study has indicated survival of cells for up to 30 weeks [59].

Sesamol has been shown to inhibit melanin synthesis in mouse melanoma cells, resulting in reduced viability and proliferation of the cells.

«In summary, our results show that Met (hionine) pre-treatment produces pronounced protection against the toxic effects induced by MeHg and / or the MeHg - Cys complex on mitochondrial function and cell viability.

, The Creators Project, July Rees, William, «Yuri Pattison: user, space», this is tomorrow, July Parson, Elly, «Blurred Lines: Yuri Pattison questions the viability of live / work spaces», Wallpaper, July Thorne, Harry, «Network Control», Frieze, July Piejko, Jennifer, «Art Basel and Liste», Art Agenda, June Fattori Franchini, Attilia, «Yuri Pattison», Kaleidoscope, Issue # 26, Winter 2015 Herbert, Martin, «British Art Show 8», Frieze, November Dell, April, «Abjection in the Digital Age at Import Projects», BerlinArtLink, September Bondi de Antoni, Alexandra, `'» Abjects» examines the vulnerability of the real world in the digital age», i - D, September Sherwin, Skye, «10 Artists You Should Meet», 10 Magazine, August Nettel, Michaela, «Yuri Pattison: «There needs to be more knowledge sharing within the London art community», www.a-n.co.uk, July van der Heide, Bart, «Yuri Pattison», interview, Mousse # 49, June 2015 Bondi de Antoni, Alexandra, «cosmos carl», i - D, June Pattison, Yuri, «The Crypt of Civilization 1940 — 2015 ---------8113», commission, Art Papers, May Joel, Dean, «Morphing Overnight», this is tomorrow, April Guggenheim, Katie, Sleek Magazine No. 45, Spring 2014 Khan, Nora N., «Free Traveller at Cell Project Space», DIS Magazine, November Grace, Banks, «Installations, installations and... installations», Elephant Frieze Review, October Dixon, Tim, «Yuri Pattison: Free Traveller» review, this is tomorrow, October Thorpe, Harriet, «Yuri Pattison: Free Traveller», Studio International, October Benson, Louise, «Free Traveller» interview, POST Matter, www.postmatter.com, September Hothi, Ajay, «Lonely Arts», Art Monthly # 379, September Rochat, Jeanne - Salomé, «colocation, time displacement» feature, Novembre Magazine # 9, Spring 2014 Archey, Karen, «RELiable COMmunications» cover feature & interview, Art Papers, May / June Robertson, Adi, «Reliable Communications» turns Soviet message boards into online art», The Verge, www.theverge.com, March Luke, Ben, «Web of Intrigue», The Art Newspaper Number 254, February Kay, Jean, «An Interview with Yuri Pattison», www.aqnb.com, January 2013 Davidson, Laura, «Traveling Through Layers: Yuri Pattison and his Leakers», www.rhizome.com, Jan 2012 Davies - Crook, Susanna, Yuri Pattison: Faraday Cage, interview, www.dazeddigital.com, March Nairne, Eleanor, «Yuri Pattison» focal - plane review, Frieze # 145, March 2011 Bailey, Stephanie, «Yuri Pattison, focal - plane» critic's pick, Artforum, December Symester, Chantelle, «Yuri Pattison: Focal - Plane» interview, www.dazeddigital.com, December