Researchers at the University of Palermo in Italy found that the betalains contained in prickly pears appears to protect the endothelial
cell walls of blood vessels from oxidative damage by free radicals.
Not exact matches
They found that the tumor
cells produce a protein that acts like Velcro to attach the
cells to the outer
wall of a
blood vessel.
Prof. Alon says: «Our study shows that the endothelial
cells, which were thought to be dynamic assistants in this process
of crossing
of blood vessel walls, are really more responders to the «physical work» invested by the white
blood cell motors and nuclei in generating gaps and crossing through
blood vessels.»
In experiments conducted on human lung endothelial
cells and in mice, the researchers showed that NS1 caused permeability
of the endothelium, which lines the
walls of blood and lymph
vessels.
When white
blood cells are summoned to combat invasive bacteria, they move along
blood vessels in a specific fashion, i.e., like a ball propelled by the wind, they roll along the vascular
wall to reach their point
of deployment.
T lymphocytes, immune
cells which circulate in the
blood, must migrate across the
walls of blood vessels in order to reach inflamed tissue.
However, when chronic inflammation occurs in a
blood vessel — typically in response to diabetes, high cholesterol and cigarette smoking — the smooth muscle
cells in the
walls of arteries change their behavior.
Their studies indicate that the two conditions common in sickle
cell disease, dramatically increase red
blood cells» adhesion to the lining
of blood vessels walls and the debilitating pain crises that can result.
Its attachment to
blood vessel walls might be influenced by the electric polarity
of cells there, note Liu,
of the University
of Washington in Seattle, and colleagues from Washington and Boston University.
Instead
of dispensing ink, Organovo's bioprinter uses two robotic tips to deposit globs
of cells — in this case, endothelial
cells that line
blood -
vessel walls, smooth muscle
cells that regulate
vessel dilation and contraction, and structural fibroblast
cells.
In a series
of studies this year, molecular geneticists at the University
of Pittsburgh School
of Medicine used a harmless virus to ferry new genes through the bloodstream, across
blood vessel walls, and into almost every muscle
cell in the bodies
of hamsters bred to have human genetic diseases.
A specific lung - targeting molecule is attached to the carrier's surface and the steriod, dexamethasone, an anti-inflammatory, is loaded into the nanogel, which then binds to lung endothelial
cells lining the inside
wall of the
blood vessels where it rapidly delivers the drug.
Researchers at Hokkaido University in Japan have demonstrated that a molecule, called biglycan, plays an intrinsic role in attracting tumour
cells toward the inner
wall of tumour
blood vessels.
When cancer
cells interact with the
walls of the
blood vessels, EPHA2 is activated and the tumour
cells remain inside the
blood vessels.
By softening their bulky nuclei and pushing them to the front edge
of their
cells, white
blood cells probe apart scaffolding in the
blood vessel walls and squeeze through, researchers report online today in
Cell Reports.
In this study, NIH scientists used mouse models to show that anthrax toxin proteins work by specifically targeting the
cells that line the inner
walls of the
blood vessels feeding the tumor.
KLF4: Selectively lowering levels
of klf4 in smooth muscle
cells in
blood vessel walls causes beneficial changes in the behavior
of these
cells.
Recent publications support the hypothesis that MSCs develop from the
blood vessel wall and belong to a subset
of perivascular
cells (i.e., pericytes).
These abnormal
cells — in the case
of pulmonary hypertension, those that line the
blood vessels leading to the lungs — release signals that stimulate the growth
of small new
blood vessels to feed the renegade
cells, allowing further proliferation, and thickening
of the
vessel walls.
High sodium diets are commonly used to study diet induced hypertension, since increasing levels
of circulating sodium cause
cells to release water (due to osmotic pressure) which elevates the pressure on
blood vessel walls.
His team applied, among others, techniques
of confocal microscopy and
cell sorting by flow cytometry which led to the discovery in human muscle biopsies that these myoendothelial
cells are located adjacent to the
walls of blood vessels.
The oils help relieve the itching and irritation
of hemorrhoids, while the herbs treat the skin and the
blood vessels through the
cell walls.
AGEs not only age
cells — they bind to the
walls of blood vessels, causing them to stiffen.
It does an excellent job
of widening the
blood vessels by relaxing muscle
cells in the
vessel walls to regulate
blood pressure.
Research has shown that curcumin promotes healthy function
of the endothelium, the thin layer
of cells that creates an interface between circulating
blood and the
vessel wall.
There are multiple factors that can cause inflammation and damage
of the endothelium, the layer
of cells that form the inside
wall of every
blood vessel in your body:
• widespread effects on circulation, muscles and sugar metabolism • raised heart rate • increased heart output • increased rate and depth
of breathing • increased metabolic rate • increased force
of muscular contraction • delayed muscular fatigue • reduced
blood flow to bladder (muscular
walls relax and sphincters contract) • reduced
blood flow to intestines • increased
blood pressure • increased sugar (glucose) in the
blood • increased break - down
of glucose for energy *, especially in muscle
cells • increased free fatty acids in the
blood * • more oxidation
of fatty acids to produce energy * • more ATP (the
cells» primary energy compound) produced * •
blood vessels constrict
In addition to the niacin it supplies, brown rice may also help raise
blood levels
of nitric oxide, a small molecule known to improve
blood vessel dilation and to inhibit oxidative (free radical) damage
of cholesterol and the adhesion
of white
cells to the vascular
wall (two important steps in the development
of atherosclerotic plaques).
When the
walls of blood vessels lose elasticity excess fluids and waste products, instead
of being excreted, press towards the fat tissue where they attach to the fat
cells, thus causing swelling and cellulite.
The only effective way
of treating cellulite is addressing the above mentioned causes, focusing on strengthening the connective tissue (collagen) and muscles found under the skin, a long - term weight loss (burning fat slowly and systematically), slowing down the ageing process
of the skin
cells, improving
blood circulation and strengthening
blood vessel walls, detoxification
of the body and liver, and improving overall health.
They also prevent LDL oxidation, and inhibit SMC proliferation and adhesion
of inflammatory
blood cells to
vessel walls.
Atherosclerosis is caused by oxidized lipids that overwhelm the
cells sent to clean them up when they irritate
blood vessel walls; the fatty deposits that narrow
blood vessels are made up
of lipids and dead
cells.
Originating from epithelial
cells (skin
cells that cover the lining
of body surfaces), Carcinomas can occur on the skin, bladder
wall, and
blood vessels that then pass into the surrounding tissues and organs.
also helps to support the
walls of the
blood vessels, and thus improves the body's ability to distribute oxygen - rich
blood and iron to all
cells, thereby facilitating healing.