Sentences with phrase «cells bax»

In healthy cells Bax is present as a soluble, single protein, which moves back and forth between the cytoplasm and the surface of mitochondria.

Not exact matches

The figure shows a confocal microscopy image of a mammalian cell undergoing apoptosis with the mitochondria stained in magenta and the protein Bax in green.

The zooms are super-resolution microscopy images of Bax assemblies shaped as lines, arcs and rings observed in mammalian cells.

This gave them images showing how Bax proteins gathered on mitochondria of cells under stress in cell - death mode.

If a cell is under stress, Bax proteins deposit on the surface of mitochondria in symmetrical pairs.

Previously, Jonathan Tilly, a reproductive biologist at Massachusetts General Hospital in Boston, found a striking correlation between high levels of a protein called Bax (a key regulator of apoptosis) and cell death in healthy ovaries.

Release of cytochrome c, Bax migration, Bid cleavage, and activation of caspases 2, 3, 6, 7, 8, and 9 during endothelial cell apoptosis.

Pro-apoptotic bax and bak control beta - cell death and early endoplasmic reticulum stress signalling.

Glucose deprivation induces an atypical form of apoptosis mediated by caspase - 8 in Bax -, Bak - deficient cells.

STAT1 activation causes translocation of Bax to the endoplasmic reticulum during the resolution of airway mucous cell hyperplasia by IFN - γ.

Its major target genes include proapoptotic genes Bax, Puma and Noxa, cell cycle regulator p21, and the senescence - inducing gene Plasminogen activator inhibitor 1 [5].

By examining this damage, it was found that the Bax / Bcl2 ratio, a parameter that is indicative of the apoptosis status [21], was increased in the testes of IVC - derived males, suggesting that there were a high number of apoptotic cells in that tissue, and this was confirmed by TUNEL assay.