Not exact matches
Philippa Taylor explained why she thought it was an encouraging discovery: «There could be real benefits for some people, particularly young girls or people who are going through cancer treatment or
chemotherapy and that destroys any chance of having their own eggs and growing eggs
cells so if you can remove ovarian tissue, grow some egg
cells outside the womb and implant them
after the treatment then that could be very positive.»
Apparently cancer stem
cells are the reason cancer often recurs even
after chemotherapy and remission.
Approximately one year
after successful treatment with cytotoxic
chemotherapy and radiotherapy, patients with advanced Small
Cell Lung Cancer (SCLC), which primarily affects heavy smokers, generally relapse with recurrence of tumours that are resistant to further
chemotherapy.
The team found that
after exposure to
chemotherapy, the
cells began developing physical markings usually seen in CSCs, including receptors on the
cell surface to which specific proteins can bind.
Patients with metastatic non-small
cell lung cancer will always progress
after chemotherapy, so most patients go on to be treated with immunotherapy, a type of therapy that uses the body's immune system to fight cancer.
By hitting breast cancer
cells with a targeted therapeutic immediately
after chemotherapy, researchers from Brigham and Women's Hospital (BWH) were able to target cancer
cells during a transitional stage when they were most vulnerable, killing
cells and shrinking tumors in the lab and in pre-clinical models.
By hitting breast cancer
cells with a targeted therapeutic immediately
after chemotherapy, researchers were able to target cancer
cells during a transitional stage when they were most vulnerable.
To test this, the researchers treated the
cells with a variety of targeted therapeutics immediately
after chemotherapy.
PARP inhibitors prevent cancer
cells from repairing themselves
after experiencing DNA damage (for example from
chemotherapy or radiation).
Loss of either GSTO1 or RYR1, the researchers report, decreased the number of cancer stem
cells in the primary tumor, blocked metastasis of cancer
cells from the primary tumor to the lungs, decreased the duration of
chemotherapy required to induce remission and increased the duration of time
after chemotherapy was stopped that the mice remained tumor - free.
Cancer stem
cells, a type of self - renewing
cell found in tumors, are of particular interest because they are the main
cell type responsible for tumor progression and for resistance to
chemotherapy and radiotherapy, and therefore a major cause of tumor recurrence
after treatment.
After exposure to
cell - stressing x-rays or
chemotherapy drugs, young mice went gray in an unexpected way.
«Many
chemotherapy drugs leave a small amount of cancer stem
cells that cause a renewed outbreak of the disease
after a few years.
After cancer
chemotherapy failed, Brown needed a stem
cell transplant for his leukemia.
The team at Barts Cancer Institute, part of Queen Mary University of London, have found that a molecule, called focal adhesion kinase (FAK), signals the body to repair itself
after chemotherapy or radiotherapy, which kill cancer
cells by damaging DNA.
A novel mechanism — similar to how normal tissue stem
cells respond to wounding — might explain why bladder cancer stem
cells actively contribute to chemo - resistance
after multiple cycles of
chemotherapy drug treatment.
The rate of JAK2 amplification in these tissues was similar to samples obtained
after chemotherapy, suggesting that JAK2 plays a supporting role in drug resistance and cancer stem
cell - like features.
Gene expression profiling tests, such as Oncotype Dx, analyze the patterns of 21 different genes within cancer
cells to help predict how likely it is that a women's cancer will recur within 10 years
after initial treatment and how beneficial
chemotherapy will be to her.
Pattern of employment and associated factors in long - term lymphoma survivors 10 years
after high - dose
chemotherapy with autologous stem
cell transplantation.
Clinicians have historically been hesitant to treat HIV patients with stem
cell transplant due to concerns that their immune systems would not effectively recover
after intensive
chemotherapy or that the procedure would cause excessive toxicities or infections post-transplant.
A Phase 3 Open - Label Randomized Study of Quizartinib (AC220) Monotherapy Versus Salvage
Chemotherapy in Subjects with FLT3 - ITD Positive Acute Myeloid Leukemia (AML) Refractory To or Relapsed
After First - line Treatment With or Without Hematopoietic Stem
Cell Transplantation (HSCT) Consolidation
Some patients will receive
chemotherapy after surgery to help treat any cancer
cells that went undetected and therefore could not be removed during surgery.
Chemotherapy is usually given before or
after surgery to reduce or destroy any remaining cancer
cells.
A new breast cancer clinical trial is testing the idea a major reason why breast cancer returns
after treatment and spreads to other parts of the body is because current
chemotherapy and radiation treatments do not kill the cancer stem
cells.
After the
chemotherapy drug has eliminated enough of the most prolific cancer
cell types, the other
cells that have survived are resistant to the drug and now have less competition for space and nutrients.
Participants are being asked to take part in this study because they have advanced or metastatic non-small
cell lung cancer that has recurred or progressed
after previous
chemotherapy (s) including a platinum - based treatment.
It is thought that the treatment may help to «mop up» any cancer
cells that are left behind
after chemotherapy.
Chemotherapy — chemotherapy may be required before surgery (to shrink the tumor and / or control spreading), after surgery (to eliminate any cancerous cells still presen
Chemotherapy —
chemotherapy may be required before surgery (to shrink the tumor and / or control spreading), after surgery (to eliminate any cancerous cells still presen
chemotherapy may be required before surgery (to shrink the tumor and / or control spreading),
after surgery (to eliminate any cancerous
cells still present), or both.
Olaparib is a PARP inhibitor, which is already used to treat certain ovarian cancer patients and prevents damaged cancer
cells from repairing themselves
after chemotherapy or radiotherapy.
That happened right before my autologous stem
cell transplant,
after I'd done one more round of
chemotherapy before my stem
cells were harvested.
Audi spent a couple of days in the hospital on supportive care
after starting
chemotherapy to help avoid side effects of tumor lysis, a syndrome that can occur and make the patient very ill when a large volume of tumor
cells are rapidly killed by
chemotherapy.
If your dog is undergoing
chemotherapy or radiation, it is advisable to only use supplements that improve
cell strength such as homeopathic natural remedies and anti-oxidants before and
after treatment in order to avoid protecting
cells that are being killed during treatment.
To ensure that all the cancer
cells are killed
chemotherapy has been shown to be effective and usually starts 1 week
after surgery.
This surgery will need to be much more aggressive to make sure they are able to get all the way to the
cells that are producing the cancer,
after the removal of the tumors, he will again be treated with the cryosurgery and implantation of
chemotherapy slow release beads.