Sentences with phrase «cells as a survival mechanism»
The rationale is that chemotherapy and immunotherapy can induce autophagy in tumor cells, which in turn is used by tumor cells as a survival mechanism to resist pharmaceutical invention.
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Similar to capsaicin, tumor necrosis factor is suspected to both induce and reduce cancer cell growth, and was shown to commit cells to survival when stimulating EGFR transactivation mechanisms, indicating that EGFR could act as a molecular switch determining the antiapoptotic effect of tumor necrosis factor (50).
The study, recently published in the journal Molecular Cancer Therapeutics, showed that dinaciclib disrupted a cell survival mechanism known as the unfolded protein response (UPR).