Sentences with phrase «cells blocks multiple»

Targeting stromal cells as well as the cancer cells blocks multiple cell signalling pathways that are used by cancer cells to become aggressive.

Not exact matches

They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

This result, effectively a method for blocking the spread of alphaviruses between cells, is one that could eventually lead to a single vaccine that protects against multiple viruses.

Furthermore, these antibodies prevent CHIKV from both entering and exiting cells, whereas prior studies of neutralizing antibodies to CHIKV and multiple other classes of viruses have focused on the capacity to block viruses from entering a cell.

The work contradicts previous studies that found that multiple types of unidentified supporting cells transform into hair cells when Notch signaling is blocked.

May 10, 2006 Selectively blocking inflammatory signals may protect mice from MS A new way to preserve the cells that surround and protect nerves could lead to new treatments for demyelinating diseases such as multiple sclerosis, a research team reports in the May 10, 2006 issue of the Journal of Neuroscience.

Their surprising discovery demonstrates that the vitamin A derivative ATRA (all - trans retinoic acid), a treatment for APL that is considered to be the first example of modern targeted cancer therapy, can block multiple cancer - driving pathways and, at the same time, eliminate cancer stem cells by degrading the Pin1 enzyme.

Bradner and Mitsiades had reported in Cell in 2011 that the inhibitor blocks the Myc cancer gene and thereby slows the growth of multiple myeloma tumors in mice.

Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells.

Fab fragments can be used to block endogenous immunoglobulins on cells, tissue, or other surfaces, and to block the exposed immunoglobulins in multiple labeling experiments using primary antibodies from the same species.

The researchers are reporting preclinical findings for a potential two - treatment strategy to block multiple mechanisms of cancer cell metabolism in pancreatic cancer at the American Association for Cancer Research Annual...

Kvansakul found that the viral protein blocks multiple pro-apoptotic proteins in host cells, and that in a mouse model of Burkitt lymphoma it also renders chemotherapy agents ineffective, making it a potent oncogene.

February 10, 2015 New screening tool could speed development of ovarian cancer drugs University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis.

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis.

One, Brawl On Cell Block 99 (B), depicted Vince Vaughn kicking multiple peoples» heads to jelly in canvas prison shoes while spouting the flowery, Nic Pizzolatto-esque tough - guy dialogue of director S. Craig Zahler (Bone Tomahawk).