A second set of cellular level events involves uptake of iodine into thyroid
cells by a protein referred to as the sodium - iodide symporter (and abbreviated as «NIS,» where the «N» comes from «Na,» which is the scientific abbreviation for the element sodium).
Not exact matches
As the video explains, these traits are due to the tiny molecular machines in our
cells known as
proteins, which are encoded
by bits of DNA called genes.
In comparison to animals, single -
celled fungi are incredibly efficient at converting carbohydrates into
protein: a pound of sugar yields half a pound of fungal biomass, beating mammals and fowl
by orders of magnitude.
Chicago, GenomeWeb — A new study
by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7
protein expression test using Epic Sciences» non-EPCAM-based circulating tumor
cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.
Its drug Niraparib kills cancer
cells by inhibiting the production of
proteins called PARPs, which help repair damaged DNA strands, thereby hastening the death of some types of cancer
cells.
What about some 2,000
proteins that are used
by a human
cell as enzymes?
DNA / RNA and
proteins are
by far the most important components of a living organism, carrying out virtually every function in a
cell.
The release of inflammatory chemicals called «cytokines» (
proteins secreted
by specific
cells involved in immunity and in inflammation) leads to biochemical reactions involving neurotransmitters.
We can compare the diverse tasks performed
by a colony to the many
proteins generated
by gene transcription, to various
cell types of a developing embryo, or to the firing patterns of neurons in the brain.
Spontaneous self - organization is invoked
by biochemists in the evolution of the prebiotic world in which a variety of atoms assembled into organic molecules eventually giving rise to molecules of RNA, DNA and
proteins which led to further complex assemblies and eventually to
cells.
Vitamin C helps make collagen which is the structural
protein that imparts skin strength
by forming a mesh - work that holds together our skin
cells.
Adiponectin is a
protein hormone produced
by our fat
cells, and it serves as an important modifier of insulin metabolism.
Phosphorus is also used
by the body to synthesize
protein for
cell and tissue growth and repair.
Alternative
protein sources may include the use of
by - products currently viewed as waste or the development of new
protein sources from plants, lower order animals, or single -
cell organisms with a lower environmental impact compared with typical animal - based
protein sources.
Anabolic steroids work
by helping the body's muscle
cells produce more
protein which, as long as the athletes works out, leads to increased muscle size and strength and, at the same time, also allows the body to produce more ATP, the «fuel» muscles need to move.
Others note that shear forces from shaking are not the only issue — bursting of bubbles caused
by shaking may also damage
cells or denature
proteins.
The numbers of
cells and
proteins generated
by the immune system of some SIDS babies have been reported to be higher than normal.
According to a team of researchers led
by Dr. Michael Julius, a specific
protein in breast milk, CD14, helps jump start an infant's immune system and develop essential B
cells, which are instrumental in the development of antibodies.
By the 4 - 8
cell stage of life, human embryos have to «turn on» their own genes and start making their own
proteins.
Its cationic Q - functional chemistry reduces host
cell DNA by 4 Log Reduction Value (LRV) or greater and Host Cell Protein (HCP) load by 25 - 35 per cent, while also exhibiting very low non-specific protein binding for high yield of therapeutic prote
cell DNA
by 4 Log Reduction Value (LRV) or greater and Host
Cell Protein (HCP) load by 25 - 35 per cent, while also exhibiting very low non-specific protein binding for high yield of therapeutic prote
Cell Protein (HCP) load by 25 - 35 per cent, while also exhibiting very low non-specific protein binding for high yield of therapeutic pr
Protein (HCP) load
by 25 - 35 per cent, while also exhibiting very low non-specific
protein binding for high yield of therapeutic pr
protein binding for high yield of therapeutic
proteins.
«
By studying the ways different
proteins like keratin dynamically change within a
cell, we can better understand the progression of cancers and other diseases,» they say.
As a result, the malfunctioning
protein builds up and,
by some set of events that remains unknown, eventually kills the
cell.
Now, scientists have discovered a new way that
cells keep these genes quiet:
by chemically tagging histones —
proteins that help keep DNA tightly coiled in the nucleus.
In turn, these modifications are caused
by two specific
proteins of the so - called chromatin regulator group, on which leukemia
cells are dependent.
So, the researchers — headed
by Professor of Physics and Biological Sciences Shane Hutson and Associate Professor of
Cell and Developmental Biology Andrea Page - McCaw — targeted
cells on the back of fruit fly pupae that expressed a
protein that fluoresces in the presence of calcium ions.
The spread of cancer
by metastasis is driven
by a set of mutant
proteins called oncogenes which cause cancer
cells to multiply uncontrollably and promotes their ability to move.
The ATF6
protein is a transcription factor, meaning it helps turn other genes «off» or «on,» depending on what's needed
by the
cell.
Immunophenotyping — a laboratory procedure used to study the
proteins expressed
by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.
In Robinson's lab, Sharon studied
protein -
protein interactions within proteasomes, large multiprotein complexes that clear
cells of unwanted
proteins by degrading them into small peptide fragments.
Within individual SCN
cells, specialized clock genes are switched on and off
by the
proteins they encode in a feedback loop that has a 24 - hour rhythm.
The
protein expressed
by the gene is thought to bind to serotonin receptor molecules and ferry them to the
cell surface, positioning them to receive serotonin's signals from neighboring
cells.
«We're interrogating the tumor microenvironment,» she says, «
by looking at suppressive cues as well as
cells and secreted
proteins that protect tumors from the immune response.»
The scientists rescued the microcephaly during mouse embryonic development
by removing a
protein that caused the loss of stem
cells.
«We discovered that Neu1, a
protein nicknamed after «neuraminidase 1,» turns the absorption of sugar «on» or «off» in body
cells,
by regulating the amount of sialic acid on the surface of
cells,» Dr. Pshezhetsky explains.
A research group at the University of Basel now describes for the first time a mechanism
by which hippocampal neural stem
cells regulate their own
cell fate via the
protein Drosha.
Scientists from Moffitt reported in the Jan. 19 online edition of Cancer Research that nicotine induces the metastatic spread of lung cancer
cells by stimulating a
protein called beta - arrestin - 1.
The drug works
by inhibiting an enzyme called low molecular weight
protein tyrosine phosphatase (LMPTP), which seems to contribute to
cells losing their sensitivity to insulin.
This microscopic image of fibroblast
cells shows the induction of
cell fusion
by a newly described gene and its
protein, called myomerger.
The research team, led
by bioengineering professor Adam Engler, also found that a
protein binding the stem
cell to the hydrogel is not a factor in the differentiation of the stem
cell as previously suggested.
Other researchers have tried changing
cell behavior
by creating
protein switches from scratch, but Lim's approach — mixing and matching naturally existing
proteins — may be more versatile and practical: «It can be useful as a biotechnology device or for repairing
cells in humans.
Led
by researchers at the Cincinnati Children's Hospital Medical Center Heart Institute, the study demonstrates the gene Gm7325 and its
protein — which the scientists named «myomerger» — prompt muscle stem
cells to fuse and develop skeletal muscles the body needs to move and survive.
Endocytosis of Frizzled 4 (Fz4) in human embryonic kidney 293
cells was dependent on added Wnt5A
protein and was accomplished
by the multifunctional adaptor
protein β - arrestin 2 (βarr2), which was recruited to Fz4
by binding to phosphorylated Dvl2.
Other genes activated
by the guide RNA encode mitochondrial
proteins that help
cells regulate their energy metabolism, and trafficking
proteins that are involved in packaging and transporting other
proteins.
These
proteins, made
by our
cells, help transform chemicals in our body, functioning as a catalyst.
Other teams are trying to introduce the
proteins encoded
by the genes directly into
cells, while Yamanaka is experimenting with «microRNAs» — snippets of RNA that help regulate gene activity.
Meanwhile a team led
by Yihong Ye, a
cell biologist at the National Institutes of Health, discovered another pathway that uses different
protein workhorses to accomplish a similar off - load.
One way cancer
cells do this is
by expressing a
protein ligand that binds to a receptor on the T
cells to prevent the T
cell from recognizing and attacking the cancer
cell.
The
protein that copies viral RNA is polymerase
protein L, which conducts all the enzymatic activities needed to synthesize RNA and then add a cap structure to its end to ensure it doesn't get destroyed
by the
cell — and to ensure that it can be translated into
protein.
This raises the possibility that, like prion disease, type 2 diabetes could be triggered
by these deformed
proteins spreading between
cells or even...
After deciphering this natural differentiation process, the investigators duplicated it in the laboratory dish
by adding a sequence of
proteins, called growth factors, to the fluid bathing the stem
cells.