Sentences with phrase «cells called b»

The virus infects white blood cells called B cells and can drive the development of blood cancers, including Burkitt's and Hodgkin's lymphoma.

Most current vaccines work by stimulating a class of white blood cells called B cells to make antibodies that circulate and control infections in the blood.

His team has previously shown that using a cancer drug to wipe out immune cells called B - cells in CFS patients seems to relieve the condition.

It is a fast - growing cancer that starts in white blood cells called B cells, and it is often successfully treated with chemotherapy.

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

B - cell acute lymphoblastic leukemia (B - ALL) is an aggressive cancer that originates from a type of white blood cell called the B lymphocyte.

Stem cells that live in that bone marrow produce a specialized white blood cell called a B cell.

Not exact matches

This time, the approval is for a type of blood cancer called large B - cell lymphoma.

Each received either a placebo or a highly specialized chemotherapy drug called rituximab, which rapidly and selectively depletes B - cells.

Their randomized trial followed 161 patients treated either with a conventional immune - suppressing drug called methotrexate, or with methotrexate plus rituximab, the B - cell killer.

New research by a team of investigators at the Medical University of South Carolina (MUSC) directed by Xue - Zhong Yu, M.D., professor of Microbiology and Immunology, in collaboration with researchers at the University of Minnesota, demonstrates that one particular family of microRNAs (miRs), called miR -17-92, is responsible for the T - cell and B - cell pathogenicity that causes GVHD.

The researchers also found that treating the mice with a molecule called CTL - associated antigen - 4 immunoglobulin (CTLA4Ig) suppressed damage to liver cells infected with hepatitis B virus, suggesting that this might be a potential approach to treatment.

In this process, several hundred times more cells of the so - called myeloid lineage (thrombocytes, erythrocytes, granulocytes, monocytes) form than long - lived lymphocytes (T cells, B cells, natural killer cells) do.

He is using the virus to cure a rare form of blood cancer called EBV lymphoma, caused when B lymphocyte immune cells get infected with the Epstein - Barr virus (EBV).

The target for ibrutinib, an enzyme called Bruton's tyrosine kinase (BTK), is a key component of B - cell receptor signaling.

In the so - called humoral response, B - cells begin to secrete specific antibody proteins, which latch onto and neutralize pathogens in tissue or blood.

But rather than delivering the entire gene for the clotting - factor proteins to cells, as most gene therapies do, the researchers used the viruses to engineer immune - regulating B cells to express a fragment of the clotting factor fused to an immune molecule called an immunoglobulin.

The team discovered that the B immune cells, called B - 1a cells, ensure that enough of these oligodendrocytes are available in the developing brain to support adequate myelination.

These hiding spots are called B cell follicles.

As cells become cancerous, they produce more of a protein called b - catenin.

In collaboration with researchers at the Lead Discovery Centre of the Max Planck Society in Germany, they developed an inhibitor molecule directed against the receptors that are regulated by Cbl - b in NK cells, the so called TAM - receptors.

Austrian scientists, in collaboration with researches in Australia and Germany, have now shown that a molecule called Cbl - b acts as a molecular brake for Natural Killer (NK) cells to reject cancer.

Non-Hodgkin lymphomas are cancers that affect white blood cells of the immune system called B - lymphocytes or B cells.

Humans and their pet dogs are close, so close that they both develop a type of cancer called diffuse large B - cell lymphoma.

The team, which included members of the Health Science Center departments of medicine and biochemistry, investigators from the UT Southwestern Medical Center at Dallas and a group of collaborators from Austria, found that the gene that codes the enzyme D2 - hydroxyglutarate dehydrogenase (D2HGDH) is mutated in a subset of cancers called diffuse large B - cell lymphomas.

For example, a drug called ibrutinib has been tested in clinical trials to treat an aggressive form of non-Hodgkin lymphoma, diffuse large B - cell lymphoma (DLBCL).

In humans, scientists know a lot about the cells involved in immediate antibody production, called plasmablasts, but less about the separate group of cells responsible for the «storage / research for the future» functions, called memory B cells.

Once in contact with Tfh, some B cells become activated, migrate to an area of the follicle called the germinal center and start dividing rapidly under influence from Tfh.

The new technique, pioneered by Wilson and fellow researchers at the Emory University School of Medicine in Atlanta, saves time by using antibodies produced by so - called B cells (white blood cells that produce and then ferry them to infection sites to battle invading germs) in response to vaccines instead of to actual infections.

Called tarocin A and tarocin B, these compounds target a different part of a bacterium's cell wall, called teichoicCalled tarocin A and tarocin B, these compounds target a different part of a bacterium's cell wall, called teichoiccalled teichoic acid.

Scientists from the Würzburg University Hospital have now focused on a cell type that has received little attention so far in connection with psoriasis: the so - called B lymphocytes.

One way that a2M might perform this custodial chore is by carrying the bound b amyloid into cells where it can be degraded — a step that requires that it bind to the very same receptor that another protein, called apoE, uses to enter cells.

The engineered cells contain an antibody - like protein known as a chimeric antigen receptor (CAR), which is designed to bind to a protein called CD19 found on the surface of B cells, including the cancerous B cells that characterize several types of leukemia.

Antibody responses are initiated in lymph nodes close to the site of initial infection (so - called draining lymph nodes, or DLNs), where antigen - presenting cells, helper T cells, and antibody - producing B cells migrate to and interact to form so - called «germinal centers» and produce a highly specific antibody response.

On top of the T cell abnormalities, chronic GVHD involves antibody - producing B cells and scavenger cells called macrophages.

Called individual nucleotide resolution crosslinking immunoprecipitation (iCLIP), the technique enabled Sanford's lab to identify IGF2BP3 binding sites in several hundred RNA transcripts in two B - ALL cell lines.

Lymph nodes have microscopic compartments called «follicles,» where they store a specific type of immune cells, the B - cells.

This cytokine then stimulates B - cells in the lymph nodes to produce a molecule called a lymphotoxin.

However, the researchers observed that only 20 to 30 percent of HSCs took on this generalist role, contributing all of the most abundant types of white blood cells — called granulocytes, B cells and T cells.

The auto - reactive B cells produced autoantibodies that mistakenly targeted proteins within their own body, in particular targeting immune inflammatory molecules called interferons and interleukins.

«We note that there are two subgroups of breast tumors by epigenome: one which we have called Epi - Basal, characterized by loss of epigenetic marks causing breakage of chromosomes and the other that we have called Epi - Luminal B, that presents epigenetic inactivation of genes that should protect us from cancer and these altered cells can no longer do it.»

The evidence reported in the Cell Press journal Cell Reports on November 21st shows that the drug called Amphotericin B, which has an estimated $ 330 million in sales around the world each year, can render a protein important for antiviral defense ineffective in both cells and mice.

In a mouse model of type 1 diabetes, RGS1 affects the population of one type of T cell called a «T follicular helper cell» that is critical for B cells and antibody production, Dr. Kissler and his colleagues reported recently in Genes and Immunity.

That's because the insulin - making cells in the pancreas, called b cells, are either missing or malfunctioning.

This can be used to create batches of cells, called UCART19, for treating anyone with the particular form of leukaemia that Layla had (B - cell acute lymphoblastic leukaemia).

Some sentries of the immune system — so - called B cells, which are charged with checking out the passersby of the bloodstream — undergo a type of basic training.

Thalidomide appears to pair up with a growth factor called PDGF - B to produce more of the smooth muscle cells that repair vessel - wall defects.

This second signal can be provided by short DNA fragments called CpG oligonucleotides, which activate a protein inside B cells named TLR9.

Blincyto (blinatumomab) is designed to treat cancers expressing a molecule called CD19 — found on the surface of B cell ALL and also non-Hodgkin's lymphoma.

Important to these studies was our development and characterization of a polarized hepatic cell line, called WIF - B, which is now being used widely.