Sentences with phrase «cells called dendritic»

To fend them off, it relies on immune cells called dendritic cells, which detect invaders and then call in the cavalry of T cells to attack.

Singlet oxygen tends to rip apart tumor cells in a manner that exposes many new tumor antigens to immune cells called dendritic cells, which, like police executing a dragnet, grab the antigens and present them to T cells for closer inspection.

The informants are a group of cells called dendritic cells, which chew up infected and damaged cells and present the regurgitated pieces to T cells.

Immune cells called dendritic cells educate T cells, infection - fighting immune cells, to smell the outer surface of the skin and go there to do battle.

The study included 124 newly diagnosed patients at 25 clinical trial sites in the U.S. Two - thirds of the patients were treated with ICT - 107, an experimental vaccine based on immune system cells called dendritic cells that were exposed to six synthetic proteins, or antigens, known to be involved in GBM development.

For instance, LKB1 also helped to repress cell surface markers on immune cells called dendritic cells that fueled the allergic reaction.

Martin - Orozco believes that Th17 cells recognise tumours and, in response, release chemicals that attract immune cells called dendritic cells to the tumour.

«A personalised immunotherapy was prepared for each patient by taking a sample of their blood and extracting a particular type of immune cell called dendritic cells.

Moffitt researchers wanted to determine if it would be possible to activate the cancer - fighting properties of T cells indirectly by targeting another type of immune cell called a dendritic cell.

Not exact matches

An armada of sentinel cells, called dendritic cells, are decentrally positioned in tissues to take up pathogens.

Institute researchers also uncovered the parents (called progenitors) that produce dendritic cells.

A month after H7N7 or H3N2 infection, mice had fewer nerve cell connectors called dendritic spines on cells in the hippocampus, a brain region involved in memory.

Assembling mRNA using pseudouridine, a nucleoside variant that occurs naturally in the body, greatly reduced the tendency of immune sentinels called dendritic cells to shoot out inflammatory molecules in response, they reported in 2005.

Since a primary function of the dendritic cells is to present an antigen to T - cells, to activate the T - cells and begin the immune response, the researchers suspected that T - cell activation in the heart tissue, and perhaps heart - tissue injury caused by T - cells, might be central to the pathological heart enlargement that is called remodeling.

Writing in 2014 in the European Journal of Neuroscience, Leuner and colleagues reported that in rats with symptoms of postpartum depression (induced by stress during pregnancy, a major risk factor for postpartum depression in women), nerve cells in the nucleus accumbens atrophied and showed fewer protrusions called dendritic spines — suggesting weaker connections to surrounding nerve cells compared with healthy rats.

They discovered that a protein called TIM - 3 is found on dendritic cells in breast tumors.

Dendritic cells constantly patrol the body, sampling bits of protein found on the surface of cells or viruses called antigens.

Skin - specific dendritic cells called Langerhans cells originate in the bone marrow, but how they get to the skin, and how they maintain their numbers, had never been explained.

Normally, an immune sentinel known as a dendritic cell would seize an antigen from an invader and present it to another immune cell called a T cell.

The dendritic cells then stimulated the immune system's main fighters, called T cells, to seek out and kill cancer stem cells — something they do not normally do.

«This is important,» says Ponichtera, «because CD209a is a mouse equivalent of a molecule that in humans is called DC - SIGN, a lectin receptor on dendritic cells that senses a variety of pathogens, including the virus that causes AIDS.

Rather than round up a patient's T cells and re-engineer them in a lab to find cancer, this treatment harvests a class of immune «helpers» called dendritic cells.

A cellular protein called PAK1 stimulates the growth of dendritic spines, or protrusions, that allow communication between neurons, and Roy had a hunch that this protein — when transported into brain cells — might help bring silent engrams back into direct awareness.

In 1973, a research team headed by Ralph Steinman at the Rockefeller University also described a new immune cell type, which they called the dendritic cell for its branching, tree - like shape.

Within three years, Steinman would identify the catalyst, a newly discovered cell that he called the dendritic cell — named after the Greek word for tree because of its branched or star - like shape.

Dendritic cells were discovered in 1973 by a Canadian immunologist called Ralph Steinman while he was working in the lab of Zanvil Cohen at the Rockefeller University in New York.

Although investigators have not yet identified which cells carry Sema4a in tumors and boost regulatory T cell function, the scientists did report that immune cells called plasmacytoid dendritic cells (pDCs) provided more than half of the Sema4a in tumors in this study.

The approach developed by the MGH team starts with the engineered protein, which in this case fuses an antibody fragment targeting a protein called mesothelin — expressed on the surface of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a protein from the tuberculosis bacteria that stimulates the activity of dendritic and other immune cells.

These cells, along with dendritic cells, recognize the incoming undigested food particles, toxic agents, and bacterial components as foreign invaders, and present them to cells of the adaptive immune system called T and B lymphocytes, leading to clonal expansion (proliferation or multiplication of specific subsets of T and B cells) and recruitment of more pro-inflammatory immune cells to the gut through a process called leukocyte homing.

Specifically, T α 1 has been shown to enhance the function of certain immune cells called T and dendritic cells.

For instance, when you swallow a capsule it travels through the gastrointestinal system where immune cells, called dendritic cells «police» the contents to decide if it is «acceptable or not.»