Sentences with phrase «cells called fibroblasts»

The adult human heart is only half muscle; the other half is made of support cells called fibroblasts that help repair wounds and form scars around damaged tissue.

However, research in Dr. King's lab has suggested a potentially more effective therapy that uses connective - tissue cells called fibroblasts.

Researchers generally attribute tissue thickening (and ensuing damage to small blood vessels) to hyperactivation of skin cells called fibroblasts.

In research published in the current issue of Cell, scientists in the laboratory of GICD director Deepak Srivastava, MD, directly reprogrammed structural cells called fibroblasts in the heart to become beating heart cells called cardiomyocytes.

In fact, about a year ago, Jerry Shay and his colleagues at the University of Texas Southwestern Medical Center in Dallas showed that adding the enzyme to normal connective tissue cells called fibroblasts extends their life - span (ScienceNOW, 13 January 1998).

For the new study, the team used a cell - reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate human DRG - type sensory neurons from ordinary skin cells called fibroblasts.

Another option is to take a skin sample, culture cells called fibroblasts and freeze them.

Researchers from the UNC School of Medicine have discovered that cells called fibroblasts, which normally give rise to scar tissue after a heart attack, can be turned into endothelial cells, which generate blood vessels to supply oxygen and nutrients to the injured regions of the heart, thus greatly reducing the damage done following heart attack.

Skin - producing cells called fibroblasts from the tip of an adult mouse's tail have been reprogrammed to make eggs, Japanese researchers report online October 17 in Nature.

These were surrounded by skin - like cells called fibroblasts, which form the heart's connective tissue.

The researchers — James Robl, a developmental biologist and his colleagues at the University of Massachusetts at Amherst, and Steve Stice at Advanced Cell Technology in Worcester, Massachusetts — inserted a marker gene fused with a gene for resistance to the chemical neomycin into a culture of connective tissue cells called fibroblasts.

Ding's team took cells called fibroblasts from the connective tissues of mouse fetuses and bathed them in a cocktail of the four polyarginine - tagged proteins for 12 hours, then they removed the reprogramming proteins for 36 hours, and repeated this cycle four times over.

Ueli Schibler of the University of Geneva showed in 1998 that the per genes of rat connective - tissue cells called fibroblasts are active according to a circadian cycle.

JOE PALCA: Well, John, what they did was they - instead of starting with embryos and using those to derive embryonic stem cells, they started with skin cells, or actually precursors to skin cells called fibroblast, that we all have in our skin.

Not exact matches

These cells, called fibroblasts, help close wounds after skin has been cut.

This microscopic image of fibroblast cells shows the induction of cell fusion by a newly described gene and its protein, called myomerger.

A new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

The researchers found that, in response to the maximum tolerated doses of several commonly used chemotherapy drugs, breast cancer - associated fibroblasts secrete large amounts of cell signaling proteins called ELR + chemokines.

The study team removed fibroblasts (skin cells) from DBA patients, and in cell cultures, using proteins called transcription factors, reprogrammed the cells into iPSCs.

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

The tissue, called the stroma, includes fat cells, or adipocytes, that provide padding; fibroblasts, which make the framework for tissue; pericytes in blood vessels, which are contractile cells that help regulate blood pressure; as well as myoepithelial cells comprising the outer layer of the ductal system through which milk flows.

The orbital remodeling in TED is likely induced by infiltrating T lymphocytes and mast cells, which activate orbital fibroblast effector cells to either proliferate and form scar - producing cells called myofibroblasts or turn into pro-inflammatory fat cells.

Cells called cancer - associated fibroblasts arrange a normal meshwork of fibers into straight tracks, cell biologist Begum Erdogan of Vanderbilt University in Nashville and colleagues reported December 13 at the annual meeting of the American Society for Cell Biolcell biologist Begum Erdogan of Vanderbilt University in Nashville and colleagues reported December 13 at the annual meeting of the American Society for Cell BiolCell Biology.

As controls, fibroblasts and secretions from normal lab rats, mice, and another rodent called the spiny mouse were powerless to stop the human cancer cells growing.

The team studied skin cells, called dermal fibroblasts, that help hair follicles develop, wounds heal, and generally maintain the structural integrity of skin.

Earlier laboratory studies had shown that fetal fibroblasts, closely related cells from the fetus, respond to tamoxifen by producing a natural peptide called transforming growth factor beta - 1 (TGF beta - 1).

«It's abdominal obesity, and even more specifically, levels of a protein called fibroblast growth factor - 2 that may be a better indicator of the risk of cells becoming cancerous.»

When stimulated by molecules called fibroblast growth factors, this receptor, known as FGFR3, prevents the cells from maturing and impedes bone formation.

The experiment shows that β1 - integrin — one of 28 types of integrin — maintains a link between the stem cell and its environment, and interacts biochemically with a growth factor called fibroblast growth factor [FGF] to promote stem cell growth and restoration after muscle tissue injury.

The research team, spearheaded by postdoctoral fellow Yajie Liang, Ph.D., wondered whether the cells» survival could also be enhanced with steady doses of a compound called basic fibroblast growth factor (bFGF), an «energy drink» that spurs cells to grow.

Xu and his team, which includes researchers from Penn's departments of Dermatology and Biology, as well as the New Jersey Institute of Technology, started with human skin cells called dermal fibroblasts.

«Half of the cells in the heart are fibroblasts, so the ability to call upon this reservoir of cells already in the organ to become beating heart cells has tremendous promise for cardiac regeneration.

The researchers then successfully prodded what they call keratinocyte - derived iPS cells or KiPS cells to distinguish them from fibroblast - derived iPS cells into becoming all the cell types in the human body, including heart muscle cells and dopamine - producing neurons, which are affected by Parkinson's disease.

In these studies we have shown that losartan treatment targets specific cells within the sclera called fibroblasts.

She recommends Clarins Multi-Active Day ($ 54, clarinsusa.com), which uses an encapsulated teasel extract that targets the key youth cell of the skin (called a fibroblast).

The cells responsible for the production of the fibers that makes this connective tissue are called fibroblasts, and if these cells are overactive, this can cause an abundance of fibrous tissue, resulting in a slow - growing mass near or on the skin.