Too much p53 in bone - making
cells called osteoblasts dials down a gene, H19, and a related protein, decorin, that would otherwise help stem cells mature (differentiate) to become normal osteoblasts.
Then bone - making
cells called osteoblasts and bone - absorbing cells called osteoclasts grow and sculpt new bone at the site of fracture.
THE METHODS In 2000, Gerard Karsenty, a molecular geneticist at Columbia University in New York City, discovered that leptin, a hormone made by fat cells, helps mold and repair the skeleton by acting upon bone - building
cells called osteoblasts.
The stretched cells turned into bone - making
cells called osteoblasts, Chen's team reports in the April issue of Developmental Cell.
Bones need a constant new creation of cells specific to their tissue, including the bone - producing
cells called osteoblasts.
The parasites might trigger these problems, the scientists hypothesized, by upsetting the normal balance between cells known as osteoclasts, which dissolve bone, and
cells called osteoblasts, which build it back up.
Ordinarily, bone is built up by
cells called osteoblasts and reabsorbed during growth and healing by cells called osteoclasts.
Not exact matches
Mesenchymal stem
cells express a surface protein
called α4β1 integrin as they turn into
osteoblasts.
The first protein is
called osteocalcin and is produced in the bone by specialized
cells charged with building bone
called osteoblasts.
I think that probably the signs of pano or the actual development of enostosis, as some prefer to
call it, in the hemophiliac dog come about via bleeding in the marrow with
osteoblast (bone depositing
cells) activity.