Stern's aim was to define how cervical
cells change during cancer progression, and if dysplasia was a step in this process from normal cell to malignant tumor.
«Over the past ten years, several research groups, including our own, have shown the importance of certain immune cell subsets in preventing or exacerbating heart disease in mice, but we are just beginning to understand how the metabolism and function of these immune
cells change during cardiovascular disease progression in humans,» says Hedrick.
The new method, published today in the journal Nature Biotechnology, has implications for better understanding how different groups of
cells change during disease progression, in response to drug treatment, or across evolution.
UBC's Shernaz Bamji and Stefano Brigidi have discovered how brain
cells change during learning and memories.
LifeTime proposes to go far beyond providing static tissue maps and to track, understand and predict how the molecular make - up of
cells changes during human diseases and ultimately intervene.
Not exact matches
At Key Stage 3 (age 11 to 13 +, Years 7 to 9) schools have to teach: that fertilisation in humans and flowering plants is the fusion of a male and a female
cell; about the physical and emotional
changes that take place
during adolescence; about the human reproductive system, including the menstrual cycle and fertilization; how the foetus develops in the uterus, including the role of the placenta.
During intense or extensive exertion, the sickle hemoglobin can
change the shape of red blood
cells from round to quarter - moon, or «sickle.»
Proteins will repair your
cells during all the
changes your body will go through.
Exposure to dioxins
during pregnancy harms the
cells in rapidly -
changing breast tissue, which may explain why some women have trouble breastfeeding or don't produce enough milk, according to a University of Rochester Medical Center study.
Secretion of the hormones estrogen and progesterone set the stage for dramatic
changes that take place in the breast
during pregnancy: a massive proliferation of mammary epithelial
cells, and the formation of thousands of ductal structures, which support milk production and transport
during lactation.
«When a new substance forms
during a chemical reaction, many students think that the atoms and molecules have actually
changed into something new, whereas they simply rearranged, that the mass increase of plants is due to minerals in the soil, or that
cell division alone accounts for animal growth,» said Cari Herrmann Abell, a senior research associate at Project 2061.
Even after the principles of epigenetics came to light, it was believed that methylation marks and other epigenetic
changes to a parent's DNA were lost
during the process of
cell division that generates eggs and sperm and that only the gene sequence remained.
Plath's team found that the
changes that happen in
cells during reprogramming occur in a sequential stage - by - stage manner, and that importantly, the stages were the same across all the different reprogramming systems and different
cell types analyzed.
They found that STAT6 - IP prevented RSV - induced
changes to airway
cells called alveolar macrophages, which can promote asthma - like responses both
during and following viral infections.
It has been particularly difficult to measure
changes in electrical functions of
cells grown within Organ Chips that are normally electrically active, such as neuronal
cells in the brain or beating heart
cells, both
during their differentiation and in response to drugs.
Using advanced laboratory techniques, the scientists tracked
changes in peanut - specific T
cells in five participants
during the first 18 months of peanut immunotherapy.
When Orlando and colleagues examined horse DNA for genes that may have rapidly
changed during domestication, they too found genes involved in neural crest
cell function.
The new technique could also be useful in understanding how stem
cells change oxidation properties
during differentiation into other
cell types.
Ideally, we want to create transition media formulations that subtly
change during cell type specialization, mimicking the human embryo.»
The study involved extracting Ribonucleic acid or RNA — found in the
cells of all living organisms — to develop a transcriptome — the gene readouts in a
cell — to examine what occurs
during the different developmental stages of the cockroach pregnancy and to explore if those
changes hold wider applications for other mammals.
A native Australian grass that «plays dead»
during droughts and selectively culls its own
cells to survive could provide genetic keys to help world food crops like chickpea withstand global climate
change.
Even in the half or so of all diabetes cases that seem to be related to genes that have programmed a person's
cells to need less fuel, exercise and moderate diet
changes can work wonders if the progress of insulin resistance is noticed soon enough
during regular checkups.
The research, published in the journal Scientific Reports, shows for the first time that the way in which fat is made within the body is not «pre-programmed»
during the early years of development as previously thought but even in adulthood
cells can be influenced by our environment to
change the type of fat that is formed.
This suggests that Drosophila neural stem
cells changed minimally
during the fly's evolution from its ancestors, which did not undergo metamorphosis.
In addition, they also counted the numbers of various types of single -
celled organisms called testate amoebae, whose population
changes depending on the amount of water in the bog, giving an indication of how wet or dry the climate was
during different periods.
The size of the brain's ventricles — cerebrospinal fluid - filled spaces deep within the brain — became progressively larger
during the course of treatment, and
changes were also seen within the subventricular zone, one of two structures in which new brain
cells are generated in adults.
A study of the way malaria parasites behave when they live in human red blood
cells has revealed that they can rapidly
change the proteins on the surface of their host
cells during the course of a single infection in order to hide from the immune system.
The
cell changes, known as an epithelial to mesenchymal transition, or EMT, are normal and helpful
during wound healing, but problematic when cancer
cells spread from the primary tumor site to other sites in the body.
«When we got those results everybody was really excited about it, because pulling out epigenetic
changes from a
cell population
during an infection in vivo is really pretty remarkable,» Tarrio said.
«While several lipid families are well - characterized at the molecular level, the total diversity and number of unique lipids in
cells, how they
change during cellular activation, and how they differ in individuals is unknown,» said Darley - Usmar.
The study recently published in «
Cell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behav
Cell Stem
Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behav
Cell» also shows that signals secreted by the choroid plexus dynamically
change during aging which affects aged stem
cell behav
cell behavior.
Lin observed that this
change in nucleus shape is similar to what occurs
during cell division and hypothesized that there may be similar underlying mechanisms behind
cell division and regeneration.
Hutchinson - Gilford progeria is caused by a spontaneous mutation
during conception in a gene called LMNA, which encodes a protein called prelamin A. Progeria patients experience a buildup of an abnormal version of prelamin A in their
cells that, among other
changes, distorts the nucleus and alters gene expression.
«Many genes that had
changed their genetic expression also
changed their degree of methylation
during the development to mature muscle
cells, which indicates a connection,» she says.
Brown University engineers have demonstrated a technique for making 3 - D - printed biomaterials that can degrade on demand, which can be useful in making intricately patterned microfluidic devices or in making
cell cultures than can
change dynamically
during experiments.
In an article published in Science this Thursday, a team of Portuguese researchers led by Helder Maiato identifies a» Highway Code» within
cells, a finding that
changes the way we perceive how chromosomes move
during cell division.
They even have influence over the DNA in your
cell nuclei, and
change and evolve
during your lifetime, giving you an unexpected source of adaptability to cope with a world in flux.
To better understand these mechanisms, Too and colleagues infected human motor neuron
cells with EV71 and compiled a list of human proteins that showed
changes in activity
during infection.
«
During cell growth, parts of the 3D microscaffold could be removed again to study how the
cells react to the
changed environment,» Martin Wegener explains.
«Our data reveals, in exquisite resolution, that the conversation between
cells of different types
changes the
cells in a way that likely mimics what is going on
during human development,» said Treutlein at Max Planck.
The study has important implications for human health, and is particularly useful for understanding the
changes that occur in
cells during the development of the tumors that underlie cancers.
The data indicated that, like the
changes in
cell function indicated in the Integrated Immune study, crew members also have
changes in blood cytokines that persist
during flight.
Four years ago,
during a magnetic resonance experiment with tumor
cells, TUM physicist Dr. Franz Schilling found signals from a molecule that was highly sensitive towards pH
changes.
By focusing an X-ray beam onto the silver paste
during the contact formation, the researchers were able to capture the chemical and physical
changes to the solar
cell and the silver paste
during the firing process and use those data to create a better picture of what happens.
We notably follow the time course of structural
changes in response to cues that affect gene expression either transiently or permanently:
changes in genome structure
during transient hormonal response of differentiated
cells and stable trans - differentiation of B
cells to macrophages.
This relationship is perhaps most striking
during the first stages of embryogenesis, when
cells change in size and shape several fold in the absence of growth.
After some time
during which reprogramming should take place, you start to evaluate the outcome and conduct functional assays, such as patch clamp recordings in case you try to obtain neurons to prove that
cells really
change their identity.
The aims of the CEMC are to define the step-wise molecular and cellular alterations that occur
during the process of carcinogenesis; determine how environmental exposures cause key genetic mutations and epigenetic
changes that underlie carcinogenesis; and discover the impact of environmental factors on the generation and maintenance of cancer stem
cells.
The $ ẹlta $ Region of Outer - Capsid Proteinμ 1 Undergoes Conformational
Change and Release from Reovirus Particles
during Cell Entry.
First - and second - line treatment of clear
cell RCC has
changed dramatically, Dr. Eric Jonasch said
during the NCCN Annual Conference in Orlando.