Sentences with phrase «cells change during»

Stern's aim was to define how cervical cells change during cancer progression, and if dysplasia was a step in this process from normal cell to malignant tumor.
«Over the past ten years, several research groups, including our own, have shown the importance of certain immune cell subsets in preventing or exacerbating heart disease in mice, but we are just beginning to understand how the metabolism and function of these immune cells change during cardiovascular disease progression in humans,» says Hedrick.
The new method, published today in the journal Nature Biotechnology, has implications for better understanding how different groups of cells change during disease progression, in response to drug treatment, or across evolution.
UBC's Shernaz Bamji and Stefano Brigidi have discovered how brain cells change during learning and memories.
LifeTime proposes to go far beyond providing static tissue maps and to track, understand and predict how the molecular make - up of cells changes during human diseases and ultimately intervene.

Not exact matches

At Key Stage 3 (age 11 to 13 +, Years 7 to 9) schools have to teach: that fertilisation in humans and flowering plants is the fusion of a male and a female cell; about the physical and emotional changes that take place during adolescence; about the human reproductive system, including the menstrual cycle and fertilization; how the foetus develops in the uterus, including the role of the placenta.
During intense or extensive exertion, the sickle hemoglobin can change the shape of red blood cells from round to quarter - moon, or «sickle.»
Proteins will repair your cells during all the changes your body will go through.
Exposure to dioxins during pregnancy harms the cells in rapidly - changing breast tissue, which may explain why some women have trouble breastfeeding or don't produce enough milk, according to a University of Rochester Medical Center study.
Secretion of the hormones estrogen and progesterone set the stage for dramatic changes that take place in the breast during pregnancy: a massive proliferation of mammary epithelial cells, and the formation of thousands of ductal structures, which support milk production and transport during lactation.
«When a new substance forms during a chemical reaction, many students think that the atoms and molecules have actually changed into something new, whereas they simply rearranged, that the mass increase of plants is due to minerals in the soil, or that cell division alone accounts for animal growth,» said Cari Herrmann Abell, a senior research associate at Project 2061.
Even after the principles of epigenetics came to light, it was believed that methylation marks and other epigenetic changes to a parent's DNA were lost during the process of cell division that generates eggs and sperm and that only the gene sequence remained.
Plath's team found that the changes that happen in cells during reprogramming occur in a sequential stage - by - stage manner, and that importantly, the stages were the same across all the different reprogramming systems and different cell types analyzed.
They found that STAT6 - IP prevented RSV - induced changes to airway cells called alveolar macrophages, which can promote asthma - like responses both during and following viral infections.
It has been particularly difficult to measure changes in electrical functions of cells grown within Organ Chips that are normally electrically active, such as neuronal cells in the brain or beating heart cells, both during their differentiation and in response to drugs.
Using advanced laboratory techniques, the scientists tracked changes in peanut - specific T cells in five participants during the first 18 months of peanut immunotherapy.
When Orlando and colleagues examined horse DNA for genes that may have rapidly changed during domestication, they too found genes involved in neural crest cell function.
The new technique could also be useful in understanding how stem cells change oxidation properties during differentiation into other cell types.
Ideally, we want to create transition media formulations that subtly change during cell type specialization, mimicking the human embryo.»
The study involved extracting Ribonucleic acid or RNA — found in the cells of all living organisms — to develop a transcriptome — the gene readouts in a cell — to examine what occurs during the different developmental stages of the cockroach pregnancy and to explore if those changes hold wider applications for other mammals.
A native Australian grass that «plays dead» during droughts and selectively culls its own cells to survive could provide genetic keys to help world food crops like chickpea withstand global climate change.
Even in the half or so of all diabetes cases that seem to be related to genes that have programmed a person's cells to need less fuel, exercise and moderate diet changes can work wonders if the progress of insulin resistance is noticed soon enough during regular checkups.
The research, published in the journal Scientific Reports, shows for the first time that the way in which fat is made within the body is not «pre-programmed» during the early years of development as previously thought but even in adulthood cells can be influenced by our environment to change the type of fat that is formed.
This suggests that Drosophila neural stem cells changed minimally during the fly's evolution from its ancestors, which did not undergo metamorphosis.
In addition, they also counted the numbers of various types of single - celled organisms called testate amoebae, whose population changes depending on the amount of water in the bog, giving an indication of how wet or dry the climate was during different periods.
The size of the brain's ventricles — cerebrospinal fluid - filled spaces deep within the brain — became progressively larger during the course of treatment, and changes were also seen within the subventricular zone, one of two structures in which new brain cells are generated in adults.
A study of the way malaria parasites behave when they live in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single infection in order to hide from the immune system.
The cell changes, known as an epithelial to mesenchymal transition, or EMT, are normal and helpful during wound healing, but problematic when cancer cells spread from the primary tumor site to other sites in the body.
«When we got those results everybody was really excited about it, because pulling out epigenetic changes from a cell population during an infection in vivo is really pretty remarkable,» Tarrio said.
«While several lipid families are well - characterized at the molecular level, the total diversity and number of unique lipids in cells, how they change during cellular activation, and how they differ in individuals is unknown,» said Darley - Usmar.
The study recently published in «Cell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavcell behavior.
Lin observed that this change in nucleus shape is similar to what occurs during cell division and hypothesized that there may be similar underlying mechanisms behind cell division and regeneration.
Hutchinson - Gilford progeria is caused by a spontaneous mutation during conception in a gene called LMNA, which encodes a protein called prelamin A. Progeria patients experience a buildup of an abnormal version of prelamin A in their cells that, among other changes, distorts the nucleus and alters gene expression.
«Many genes that had changed their genetic expression also changed their degree of methylation during the development to mature muscle cells, which indicates a connection,» she says.
Brown University engineers have demonstrated a technique for making 3 - D - printed biomaterials that can degrade on demand, which can be useful in making intricately patterned microfluidic devices or in making cell cultures than can change dynamically during experiments.
In an article published in Science this Thursday, a team of Portuguese researchers led by Helder Maiato identifies a» Highway Code» within cells, a finding that changes the way we perceive how chromosomes move during cell division.
They even have influence over the DNA in your cell nuclei, and change and evolve during your lifetime, giving you an unexpected source of adaptability to cope with a world in flux.
To better understand these mechanisms, Too and colleagues infected human motor neuron cells with EV71 and compiled a list of human proteins that showed changes in activity during infection.
«During cell growth, parts of the 3D microscaffold could be removed again to study how the cells react to the changed environment,» Martin Wegener explains.
«Our data reveals, in exquisite resolution, that the conversation between cells of different types changes the cells in a way that likely mimics what is going on during human development,» said Treutlein at Max Planck.
The study has important implications for human health, and is particularly useful for understanding the changes that occur in cells during the development of the tumors that underlie cancers.
The data indicated that, like the changes in cell function indicated in the Integrated Immune study, crew members also have changes in blood cytokines that persist during flight.
Four years ago, during a magnetic resonance experiment with tumor cells, TUM physicist Dr. Franz Schilling found signals from a molecule that was highly sensitive towards pH changes.
By focusing an X-ray beam onto the silver paste during the contact formation, the researchers were able to capture the chemical and physical changes to the solar cell and the silver paste during the firing process and use those data to create a better picture of what happens.
We notably follow the time course of structural changes in response to cues that affect gene expression either transiently or permanently: changes in genome structure during transient hormonal response of differentiated cells and stable trans - differentiation of B cells to macrophages.
This relationship is perhaps most striking during the first stages of embryogenesis, when cells change in size and shape several fold in the absence of growth.
After some time during which reprogramming should take place, you start to evaluate the outcome and conduct functional assays, such as patch clamp recordings in case you try to obtain neurons to prove that cells really change their identity.
The aims of the CEMC are to define the step-wise molecular and cellular alterations that occur during the process of carcinogenesis; determine how environmental exposures cause key genetic mutations and epigenetic changes that underlie carcinogenesis; and discover the impact of environmental factors on the generation and maintenance of cancer stem cells.
The $ ẹlta $ Region of Outer - Capsid Proteinμ 1 Undergoes Conformational Change and Release from Reovirus Particles during Cell Entry.
First - and second - line treatment of clear cell RCC has changed dramatically, Dr. Eric Jonasch said during the NCCN Annual Conference in Orlando.
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