As we get older, brown fat
cells change into white fat cells.
When studying how normal
cells change into cancer cells, dos Santos and other cancer researchers pay close attention to gene expression.
If the Gq protein is blocked, undesired white fat
cells change into energy - consuming brown cells.
It occurs when some of the red blood
cells change into a «sickle» shape and cause a buildup of red blood cells in small blood vessels.
Not exact matches
As a cancer researcher, do you think the mechanisms of tumor growth are somehow
changing to come
into line with your perceptions, or is it possible that the process of our learning more about DNA mutations and
cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going on under our noses?
Whether it is
changing text books to teach religion as a «science,» making laws that prohibit stem -
cell research which would without question help those in need, to stopping of any kind of gay rights, trying to put religion (christianity)
into schools, a woman's right to choose, etc, etc...
Thus, the transition from instinct to reason results in the radical transformation of the animal
into man; matter as it evolves toward the
cell becomes radically transformed
into living matter; and vegetative life becomes qualitatively
changed into conscious life.
Such was the comfortable vista which, less than a century ago, began abruptly to
change beneath our gaze, something in the fashion of those organic tissues in the living body which, after long remaining harmless and dormant, their
cells apparently indistinguishable from those of the surrounding tissue, suddenly burst
into dangerous growth.
Instone - Brewer's own narrowing of the question of individual life -LRB-»... when does an embryo
change from being a bundle of undifferentiated
cells into a living human individual?»)
And let's remember that evolution, while it's a theory, is a theory about the beginning and the transformation of life based on things we have observed, namely that
cells change and mutate and that those mutations can produce
cells that are unique and new, and that it would follow that it's possible for molecules to form
into single -
celled organisms which mutate and combine
into multi-cellular organisms which mutate, adapt, and grow over time
into new forms of life.
A
change in polling foundations (home phones become
cell phones = limitations on traditional cold calling... and also the shift
into online polls).
Baylin and Johns Hopkins scientist Michelle Vaz, Ph.D., first author on the study, suspected that the interplay of epigenetic and genetic
changes may occur when normal lung
cells develop
into cancer, but, Baylin says, the timing of such
changes was unknown.
She demonstrated that early experience leads to lasting
changes in the molecular structure of the brain and discovered a gene involved in the spread of brain cancer
cells into healthy brain tissue.
Following combined exposure to the two substances, the leukemia
cells underwent substantial
changes and, to the surprise of the researchers, started to turn back
into normal blood
cells.
«When a new substance forms during a chemical reaction, many students think that the atoms and molecules have actually
changed into something new, whereas they simply rearranged, that the mass increase of plants is due to minerals in the soil, or that
cell division alone accounts for animal growth,» said Cari Herrmann Abell, a senior research associate at Project 2061.
Many of the mutations in ASD, Yan explained, result from chromatin remodeling factors, which are involved in dynamically
changing the structure of chromatin, the complex of genetic material in the
cell nucleus that condenses
into chromosomes.
«The discovery of this special class of
cells that sit right at the nerve endings where HSV - 2 is released
into skin is
changing how we think about HSV - 2 and possible vaccines,» said Corey.
A virus containing the gene that codes for two molecular «switches» essential for turning skin
cells into brown fat was used to trigger the
change (Nature, DOI: 10.1038 / nature08262).
Cultured in the lab, the
changed cells showed an ability to differentiate
into (or become) two discrete
cells found in breast tissue.
Ectonucleoside triphosphate diphosphohydrolase 2 (E-NTPDase2) is an ectoenzyme that, along with family members E-NTPDase1 and E-NTPDase3, is known to degrade the chemical compound ATP (adenosine triphosphate)
into ADP (adenosine diphosphate) for the purpose of sending messages to
cells to
change the fleet of proteins they are producing.
«If you manually put a bunch of data
into a spreadsheet and then
change the contents of one
cell, it won't update the other
cells around it.
The project's goals were to explore and describe the range of epigenetic
changes that take place in bone marrow as stem
cells develop
into different types of mature blood
cell.
Now Bruce Spiegelman at the Dana - Farber Cancer Institute in Boston and colleagues have shown that foreskin
cells from mice can be
changed into brown fat
cells.
As the heart starts pumping a primitive blood - like fluid around the body of an embryo, the
change in pressure from the flowing liquid is the cue for
cells lining the aorta to
change first
into blood stem
cells, then
into all blood -
cell types in the body.
But that
changed when Lagasse injected
cells into the belly: The mice gained weight, recovered energy, and within weeks appeared healthy.
In reaction to infection or inflammation, immune system
cells known as effector T
cells (Teffs) undergo rapid
changes - arming themselves and diversifying
into groups that target specific diseased
cells.
In cancer
cells, the protein networks that control the behavior are
changed in such a way as to cause the
cells to lose control and break away — a mutated skin
cell, for instance, might then migrate
into the bloodstream.
By analyzing chemical
changes of the IRS - 2 protein in immortalized cultures of human white blood
cells, it determined that IRS - 2 appeared in two different forms — «on,» which allows the signal to pass through, and «off,» which stops the signal from activating the
cells into M2 macrophages.
Four years ago, the research team of Pedro Herrera (University of Geneva) first cast doubt on this assumption when they demonstrated that a few alpha
cells in the pancreas of genetically modified diabetic mice
changed into beta
cells.
Sen and his colleagues tested sucralose, a popular low - calorie sweetener, on stem
cells —
cells that could
change into mature fat, muscle, cartilage or bone
cells — taken from human fat tissue.
The
change is translated
into an electrochemical signal that is picked up by nerve
cells, which relay it to the brain.
These epigenetic
changes are continuous and are at the core of how healthy
cells transform
into cancer
cells.
This research provides a new insight
into the movement of electrons that could potentially
change the way solar
cells and semiconductor devices are built.
«Disturbances to these processes may cause neuronal stem
cells to develop
into different types of
cells or may cause neurons to migrate to different locations in the brain,
changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»
He hopes to pursue projects such as developing therapeutics with chemists, working with biophysicists to study protein conformational
changes relevant to viral entry
into the
cell, and investigating cellular trafficking pathways relevant to the viral life cycle in collaboration with
cell biologists.
Although many scientists doubt that Orlic's bone - marrow stem
cells actually morphed directly
into new heart tissue, they do believe the
cells may have secreted powerful chemical cues — growth factors — or perhaps
changed into blood vessels that revitalized the hearts.
The new technique could also be useful in understanding how stem
cells change oxidation properties during differentiation
into other
cell types.
A team of researchers led by the University of California San Diego has for the first time observed nanoscale
changes deep inside hybrid perovskite crystals that could offer new insights
into developing low - cost, high - efficiency solar
cells.
Stem
cells are immature blood
cells and, in theory, introducing the gene
into them should produce a permanent
change in that individual's maturing blood
cells.
Some would simply crank their telomerase activity up even further; some would enhance the activity of drug - metabolizing enzymes that degrade the inhibitor; still others would
change their
cell surface proteins in ways that would make it harder for the drug to penetrate
into the
cell.
Simply put, they act as little computing devices that optimally gather and process information coming
into the
cell, allowing the
cells to adapt and
change their function.
They then purified messenger RNA — a molecule that plays a key role in the production of proteins — from the
cells in the animals» upper intestines, injected the mRNA
into immature eggs
cells, and looked for
changes in iron uptake.
Bio-engineers are working on the development of biological computers with the aim of designing small circuits made from biological material that can be integrated
into cells to
change their functions.
Stem
cells from umbilical cord blood are highly prized for their ability to
change into the
cells of other tissues.
Leptin, which is made by fat
cells, is thought to signal the body that it has enough energy in reserve to launch
into the growth spurt and other
changes of puberty.
Arikawa suspects that the
cells» detection of the
change from light to dark in their immediate vicinity is necessary to spur the male
into action.
In a collaborative effort between the Gladstone laboratories of Benoit Bruneau, PhD, Katherine Pollard, PhD, and Dr. Srivastava, the scientists used stem
cell technology to make large amounts of endothelial
cells from patients with CAVD, comparing them to healthy
cells and mapping their genetic and epigenetic
changes as they developed
into valve
cells.
Adult stem
cells: They have less flexibility and «stemness» to
change into different
cell types, but they can still produce new
cells, specialized to become part of a particular organ or tissue, such as muscle
cells or neural
cells.
«
Changes in metabolites can regulate earliest stages of development: Findings may offer insights
into a variety of disorders, advance embryonic stem
cell research.»
By March 2014 — about the time the epidemic was detected, but some 3 months after the first case actually occurred — the sequences had split
into two distinct lineages, one of which was characterized by a single amino acid
change in a region of the virus's surface protein and allows it to bind to
cells.