Sentences with phrase «cells change provides»

«Watching stem cells change provides clues to fighting osteoporosis in older women.»

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

This provides a game changing advantage in regenerative medicine that otherwise relied on the concept of stem cells.

We ran out of diapers on day 6 of 8, no problem — contacted the family concierge via the cell phone provided and she came and got a $ 20 note, sent a bellman to the stores off the resort and brought both the bought diapers, receipt and change back to me at the pool ---- huge tip provided to her and the bell boy, but worth it!

«This study signals a big change in thinking, because it provides simple and efficient tools for scientists to study stem cell creation in a stage - by - stage manner.

This research provides a new insight into the movement of electrons that could potentially change the way solar cells and semiconductor devices are built.

The new compound, Corin, specifically targets these epigenetic changes in cells and could therefore provide significant improvements in patients without unwanted side effects.

A native Australian grass that «plays dead» during droughts and selectively culls its own cells to survive could provide genetic keys to help world food crops like chickpea withstand global climate change.

Stem - cell research promises great changes to our lives by providing spare parts for our bodies, so extending human lifespan to...

Thus, in principle, a successful vaccine has to stimulate the first B cells in this lineage and then coax them along a fairly narrow evolutionary path until they have changed enough to provide effective protection against HIV.

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

The findings may change the clinical approach to patients with FECD, who are currently being treated as being irreversibly damaged, requiring transplants to provide a new source of healthy cells.

Frey and colleagues argue that robustness in the face of changes in the concentrations of components could provide an evolutionary advantage, insofar as it endows cells with a higher degree of flexibility.

scNMT - seq allows researchers to study the effects of changes in single cells and could provide conclusive evidence that they can develop into major differences both in development and disease.

«We've provided evidence that by acquiring the regulatory elements for NRL to shift short - wavelength cones into rods, early mammals changed one type of cell from capturing UV light — which isn't necessary at night — to something that is just extremely sensitive to light.»

Roughly 75 % of disease - causing genes in humans are also found in the fruit fly, and most of the components found in human heart cells are also found in the fly heart, thus providing a model for studying cardiovascular changes.

LifeTime proposes to go far beyond providing static tissue maps and to track, understand and predict how the molecular make - up of cells changes during human diseases and ultimately intervene.

Kathy Niakan and colleagues are providing new understanding of the genes responsible for a crucial change when groups of cells in the very early embryo first become organised and set on different paths of development.

«The human genome sequence provided a blueprint of all the protein - coding genes in the human genome for the first time,» reveals Jan Ellenberg, Head of the Cell Biology and Biophysics Unit at EMBL Heidelberg, «this changed how we go about studying protein function.»

«This provides the first plausible molecular mechanism for a cell to respond to its environment with a heritable change in phenotype,» offers Lindquist.

Cells in a tumor or tissue can change their own mechanical properties in often complex ways, using genetic programs and other feedback loops, and if jamming is to provide a solid conceptual foundation for aspects of cancer, it will need to account for this ability.

Our contributions to this field have helped to change the way endocytosis is perceived, from being simply a mechanism for signal attenuation to being a vital component of the cell signalling machinery that provides spatial and temporal dimensions to signalling events (1).

Because these cells have the capacity to detect changes in the body which are causing pain or dysfunction, they respond and communicate with the body's needs to provide the correct tools needed for healing.

Our cells in our bodies are constantly reproducing, nature is continually regenerating and growing, and as individuals, life causes each of us to change and evolve, providing our partners with more to discover and learn about us.

There are many reasons, but one of the hottest new theories is that fruits and vegetables provide powerful antioxidants that protect our cells from internal damage that can lead to cancerous changes.

They induce genetic changes and enslave surrounding normal cells, forcing them to do the disease's bidding - providing physical support, protecting them from the immune system, and more.»

Year 6 Science Assessments and Tracking Objectives covered: Describe how living things are classified into broad groups according to common observable characteristics and based on similarities and differences, including micro-organisms, plants and animals Give reasons for classifying plants and animals based on specific characteristics Identify and name the main parts of the human circulatory system, and describe the functions of the heart, blood vessels and blood Recognise the impact of diet, exercise, drugs and lifestyle on the way their bodies function Describe the ways in which nutrients and water are transported within animals, including humans Recognise that living things have changed over time and that fossils provide information about living things that inhabited the Earth millions of years ago Recognise that living things produce offspring of the same kind, but normally offspring vary and are not identical to their parents Identify how animals and plants are adapted to suit their environment in different ways and that adaptation may lead to evolution Recognise that light appears to travel in straight lines Use the idea that light travels in straight lines to explain that objects are seen because they give out or reflect light into the eye Explain that we see things because light travels from light sources to our eyes or from light sources to objects and then to our eyes Use the idea that light travels in straight lines to explain why shadows have the same shape as the objects that cast them Associate the brightness of a lamp or the volume of a buzzer with the number and voltage of cells used in the circuit Compare and give reasons for variations in how components function, including the brightness of bulbs, the loudness of buzzers and the on / off position of switches Use recognised symbols when representing a simple circuit in a diagram

Both parents shall promptly provide the other parent with updated cell and landline phone numbers and e-mail addresses when there has been a change.