Sentences with phrase «cells change their activity»

If someone wants to build a new sensor, say, to understand how cells change their activity, they'll know to go talk to the people who do nanoscale engineering at Lawrence Berkeley's Molecular Foundry, who know a lot about that.

Not exact matches

But here's the good news: Researchers biopsied the participants» muscle cells and found that while the under - 30 group that did interval training experienced changed activity levels in 274 genes, those in the plus - 64 group experienced changes in activity among nearly 400 genes.

Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).

Both ATP and ADP, known as purines, can transmit signals to cells that change their developmental activity.

They found similar changes in gene expression in the same genes with increased activity of glucose transporters in both the stem cells and the fat cells, Sen noted.

The researchers then measured cell composition and electrical activity again and found that the cells dramatically changed when they were in contact with neurons from different regions.

When pathogens infect the cells of the body, the infection sets off a chain reaction involving the immune system that changes the activity, or expression, of hundreds of genes.

Some would simply crank their telomerase activity up even further; some would enhance the activity of drug - metabolizing enzymes that degrade the inhibitor; still others would change their cell surface proteins in ways that would make it harder for the drug to penetrate into the cell.

Barreiro and colleagues took a similar approach to test for the effects of African versus European ancestry on changes in the activity of immune cells.

«There are genes and proteins that are expressed in a cell and their activity, or expression level, changes with time of day,» explained St. John.

Using in vitro, or test tube, experiments, the researchers applied these chemicals to human cancer cells to measure changes of estrogen receptor - and androgen receptor - target genes and transcriptional activity.

At the core of this cell behavior is how the loss of that single gene changes activation levels of dozens of other genes, suppressing genes associated with metastatic disease and increasing activity of genes linked to normal tissue.

«The finding that certain cell signaling lipids change the activity of an oncogenic Ras protein, suggests that we might be able to interfere with tumor progression by inhibiting the enzymes which make the specific cell signaling lipid in cells,» Buck said.

The change in vibration energy can be pinpointed by Raman mapping with a resolution of 300 nanometers, he said, allowing characterization of the activity of a single cell.

The differences between male and female iPS cells are most pronounced for one of the key processes in the field of epigenetics: DNA methylation, a modification that changes the activity of a DNA segment without changing its sequence.

Scientists have shown that this voltage change can trigger a cascade of biochemical reactions that relay messages to the cell nucleus, changing gene activity and altering cell growth and differentiation.

The nerve cell's activity was measured via concentration of calcium ion in the cell, and the team analyzed the changes in calcium concentration using a mathematical model.

«By combining in vivo multiphoton microscopy and in vivo electrophysiology, our lab is better able to visualize how cells move and change over time in the living brain and explain how changes in these glial cells alter the visually evoked neural network activity,» says Kozai.

The team used this change in the variability of the song to look at how the activity of single cells in different parts of the brain altered their activity depending on the social environment.

Fifty - three of the brain cells showed significant changes in activity as the coils rotated, reacting to field strength and polarity.

To remedy that absence, Golden's lab, along with plant physiologist Takao Kondo and colleagues at Nagoya University in Japan, developed an easy - to - read gauge of changing photosynthetic activity in colonies of the cyanobacterium Synechococcus, a blue - green alga whose one - celled organisms divide as often as once every 5 to 6 hours.

LAST FRONTIER Harvard graduate and medical student Benyam Kinde, 27, studies how genetic changes affect brain cells» activity.

For this proof of concept study, the scientists analyzed rodent cells» electrical activity for up to 30 days, reporting that the cells displayed characteristics and changes mimicking physiological responses described in literature.

«We envisage that morphological changes are likely to impact the function of chandelier cells, and consequently, alter the activity of cortical networks.

The specificity of this DNA cutting activity has made CRISPR - Cas the darling of gene therapy researchers, who have modified it to make precise changes in the genomes of cultured cells, laboratory animals, and even humans.

They report this month in the Proceedings of the Royal Society B that changes in the heartbeat due to temperature (the heart slows as it cools and then speeds back up as the fish resurfaces) and adrenaline, released from the stress of diving, alter the electrical activity of the heart cells to sustain the constant calcium cycling needed to keep the heart going.

Thorough study of changes in the gene activity regulation mechanism showed that reprogrammed and embryonic stem cells are similar.

«Now that we know exactly how changes in EMSY spur cancer cell growth, we can start to design therapies to specifically target that activity and hopefully stop it,» says senior author Douglas Levine, MD, director of the Division of Gynecologic Oncology at NYU Langone and its Perlmutter Cancer Center.

In particular, RNA enzymes can not readily adjust their activities to temperature changes likely to have happened as the earth cooled, and so can not perform the very broad range of catalytic accelerations that would have been necessary to synchronize the biochemistry of early cell - based life forms.

In agreement with predictions from these models, we show that minimal changes in the shape of the environment in which rats are exploring can substantially alter correlated activity patterns among place - modulated granule cells in the dentate gyrus.

As with many other epileptic syndromes, LKS children often resume normal brain activity around age 15, when the brain cells are reaching toward maturation, perhaps spurred by hormonal change.

Inside our cells, they can trigger processes that change gene activity and that ultimately affect how our cells behave.

And we have a potential target to be able to influence that activity to change the properties of cancer cells,» says Professor Richards.

To better understand these mechanisms, Too and colleagues infected human motor neuron cells with EV71 and compiled a list of human proteins that showed changes in activity during infection.

This approach has revealed new insights into the timing and coordination of the changes in gene activity and modifications to the DNA that occur as cells are reprogrammed from one state to another.

Tumor cells metastasized to bone modify the activity of these cells and, depending on the type of cancer, cause osteoblastic or osteolytic changes.

Dr. Tye and her team discovered a role for brain cells that secrete dopamine, dopamine neurons, in a specific brain region which showed changes in activity after social isolation.

Once the bacterial cell signaling protein cagA reaches the host cytosol, it is capable of altering subsequent generations of progenitor cells, leading to the development of cancer through changes in mitotic activity, apoptosis, cellular assembly, and signaling.26 Although it should be noted that while the presence of the cagA protein doubles the risk of gastric cancer, cagA - negative strands also increase the risk of distal gastric cancer.27 Additional H pylori virulence factors include babA2, which encodes bacterial adhesion with gastric epithelial cells, and vacuolating cytotoxin A, which is encoded by the gene vacA.28, 29 H pylori strains carrying some combination of the babA2, cagA, and vacA genes were associated with the highest risk of developing intestinal metaplasia.

This change hid Bcl - xL's binding site, preventing it from blocking the activity of cell death - promoting proteins.

«They have a device that looks like a small tool box that contains neural cells and can detect changes in their electrical activity,» Stice said.

The current report, which appears in the May 4, 2012 issue of the journal Cell Stem Cell, shows that these cells can also change their epigenomes, the patterns of DNA modifications that regulate the activity of specific genes — sometimes radically.

This is because the average length of differentiated cells is independent of changes in the meristematic activity in this case (Fig 4G).

In a pioneering study, he applied these tools to a genome - wide study of disease - related changes in the epigenome — the layer atop the genome that controls gene activity and is altered by the environment — of immune cells isolated from patients with asthma.

No significant change was observed when these expression plasmids were transfected into U3A cells, except that C / EBPα had a potent repressive activity (data not shown).

According to the findings it seems that regulation of gene activity is dependent on stuctural changes in the cell chromatine.

One study found that exposure to chronic stress actually changes the activity of the genes of immune cells — making them more likely to attack the body's own tissue and trigger an autoimmune response.

Still, other government - funded studies have made connections between cell phones» electromagnetic fields and changes in brain activity.

«These activities are leaving what we call a molecular signature in our cells, which reverses the effect that stress or anxiety would have on the body by changing how our genes are expressed,» said study author Ivana Buric in a press release.

In the book Relaxation Revolution: The Science and Genetics of Mind Body Healing, author Herbert (Benson) discusses how breathing can literally change the expression of genes, and that by using your breath, you can alter the basic activity of your cells with your brain.

The chemical changes taking place in living cells for the release of energy that is required for all the vital processes and activities of the body is known as metabolism.