The condition, also known as Lou Gehrig's disease, attacks and kills nerve
cells controlling muscles, leading to weakness, paralysis and, ultimately, respiratory failure.
Fresh insights into how
our cells control muscle development could aid understanding of muscular dystrophy and other inherited diseases.
Not exact matches
But it is not actually the crucial question, which is, What
controls the activity of the complex interacting set of genes, which produces a nerve
cell or a
muscle cell?
Protein plays many important roles, such as repairing the body's
cells, building and repairing
muscles, helping build and maintain bones, and helping
control many metabolic processes.
They are a rich source of vitamin C and flavonoids, which are powerful antioxidants, vitamin K that increases bone mass, potassium that helps electrolyte regulation, nerve function,
muscle control, and blood pressure, folate that supports red blood
cell formation and fiber.
HEALTHY
muscle cells exposed to fat can become like
cells taken from people with diabetes, with the genes that
control fat - burning permanently switched off.
«We also study how to
control living
muscle tissue by electrical stimulation of the
cell,» he says.
The investigators found that when LIF - treated
muscle stem
cells were transplanted to skeletal
muscle, they formed two to three times more
muscle fibers as
control cells did.
Inside your
cells, proteins allow your body to break down food to power your
muscles, send signals through your brain that
control the body, and transport nutrients through your blood.
Other proteins work as
muscles,
control metabolism and immune response, or transport oxygen in the red blood
cells.
Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, might damage
muscle -
controlling nerve
cells in the brain earlier in the disease process than previously known, according to research from the Cedars - Sinai Board of Governors Regenerative Medicine Institute.
The disease is known to affect motor neurons — nerve
cells that
control muscles — in the brain, brainstem and spinal cord.
Motor neurons, or nerve
cells, in the brain and spinal cord
control the function of
muscles throughout the body.
When a spinal cord injury takes place, extensions of nerve
cells from the brainstem — the region of the brain where the command and coordination for urination takes place — become disconnected from
cells in the spinal cord that
control the
muscles that squeeze or relax the bladder and open and close the urethra.
Decades of work in developmental biology have provided a start: Biologists have used mutant frogs, flies, mice, chicks, and fish to identify some of the main genes that
control a developing
cell's decision to become a bone
cell or a
muscle cell.
The media is made mostly of smooth
muscle cells that help
control the flow and pressure of the blood within.
Scientists have discovered a way in which proteins in our
cells help to
control genes in our DNA, which are involved in forming
muscle.
Moreover, her studies are the first to indicate that therapies targeted at
controlling the properties of smooth
muscle cells within lesions may be highly effective in treating a disease that is the leading cause of death worldwide.
Muscular Dystrophy is a hereditary condition marked by weakness and progressive wasting of the
muscles, while ALS impacts nerve
cells that
control voluntary
muscle movement.
The brain
controls movement by sending electrical signals to our
muscles through nerve
cells.
Searching for a way to help people regain
control over their unreliable bladders, Anthony Atala, a urologist at Children's Hospital Boston, injected stem
cells from the limb
muscles of rats into their deliberately damaged urinary sphincters, which
control flow.
The researchers traced stem
cells as they matured into motor neurons, which are the type of nerve
cells that
control muscle movement.
Whether either or both of these explanations are confirmed, the fact that individual Purkinje
cells are able to distinguish when their corresponding
muscle neurons encounter an error must be taken into account in future studies of fine motor
control.
The rare progressive condition attacks nerve
cells located in the brain and spinal cord responsible for
controlling voluntary
muscles.
Ruvkun's lab later demonstrated that the daf - 2 pathway functions specifically within the worm's neurons — and not elsewhere, such as in
muscle cells — to
control life span.
The research also answers a long - standing question about why motor neurons, the nerve
cells of the spinal cord that
control muscle movement, form much faster than other types of neurons.
For the past several years, researchers at the University of Illinois at Urbana - Champaign have been developing a class of walking «bio-bots» powered by
muscle cells and
controlled with electrical and optical pulses.
For the first time, scientists found that in spinal muscular atrophy (SMA), the affected nerve
cells that
control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the
cell.
Light -
controlled cardiac
muscle cells guide swimming of an artificial animal.
The calcium ion
controls processes ranging from
muscle contraction to
cell division.
Instead, the genetic identity of each subtype of
cells — what makes those that
control the quadriceps
muscle different from those that
control the calf
muscle for instance — is also important.
In studying the functional behavior of the brain, from
control of
muscles to the formation of memories, scientists are using such tools such as electron microscopy, recordings of electrical signals from individual brain
cells, and imaging of brain structures and processes using functional magnetic resonance imaging (fMRI), positron emission tomography (PET), and high - resolution optical imaging.
They have generated excitement over the past few decades because scientists can study them in the laboratory to discover the genetic switches that
control the development of specialized tissues in the embryo and fetus, and also because of their potential to replace body tissues that have broken down, such as pancreatic
cells in those with diabetes or heart
muscle cells in those with congestive heart failure.
Motor neuron disease (MND) is a group of diseases in which the nerve
cells in the brain and spinal cord
controlling the
muscles that enable us to move, speak, breathe and swallow slowly degenerate and die.
Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks
muscle -
controlling nerve
cells — motor neurons — in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of
muscles throughout the body.
ALS is a progressive neurodegenerative disease that affects neuronal
cells in the brain and the spinal cord, which send signals to
control muscles throughout the body.
Signals from these
cells to the
muscles weaken in victims, resulting in atrophy, speech disruptions and, eventually, total loss of
control over movement.
More than 30,000 Americans live with ALS, a condition that destroys motor neuron
cells that
control essential
muscle activity, such as speaking, walking, breathing and swallowing.
For his dissertation research, which he'll begin this fall, he will try to untangle the network of proteins that
controls how mesenchymal stem
cells differentiate into bone,
muscle, and other tissue.
Researchers in the US and Sweden say that the protein can prevent the destruction of brain
cells that are lost in Parkinson's, and protect the motor neurons which
control muscles.
The contractile activity of smooth
muscle cells in the walls of cerebral arteries determines the degree of constriction they experience (known as arterial tone) and thereby
controls blood flow.
They found that not only does the tissue harbor CBS and CSE, but CSE is also present in the smooth
muscle cells and peripheral nerves that
control erection.
They
control both the transport of ions inside the
cell itself and to the outside, all in complicated processes necessary to make the
muscle able to contract,» explains Sørhus.
These signals
control actin fibers, the
cell's
muscles: The fibers bend the
cell envelope from inside and form membrane bubbles into which the bacteria are absorbed.
In addition, their studies also had implicated the protein in pathways that
controlled cell death in heart
muscle.
A fraction of the FTD patients show symptoms consistent with ALS, a disease in which the nerve
cells that
control the
muscles, in the brain and spinal cord, are affected.
For quality
control, researchers want to figure out how to ensure that the stem -
cell - derived cardiac
muscle or neural progenitor or pancreas
cells (or whatever) are as pure as possible.
In the present seminar, I will summarize our findings concerning the role of Srf in myofibers to
control muscle mass and I will present recent data identifying Srf as a master regulator of
muscle stem
cell fusion and demonstrating the implication of F - actin architecture in this process.
This consortium of researchers, clinicians, and patients, has «systematically investigated and graded» evidence for over 35 «alternative» treatments for Amyotrophic Lateral Sclerosis (ALS, aka Lou Gehrig's disease), a fatal disease that destroys the nerve
cells that
control voluntary
muscle movement.
Motor neurons that
control foot
muscles are about three feet long, so neurotransmitters must be moved a yard from their origin in the
cell body to the location where they can signal the
muscles, Zhang says.