Sentences with phrase «cells express fewer»

The fact that these stem cells express fewer metabolic genes might be one way to protect the cells from the daily grind faced by their peers, and to limit the production of metabolic byproducts that can damage DNA.

Not exact matches

Proliferating Cells Express mRNAs with Shortened 3» Untranslated Regions and Fewer MicroRNA Target Sites

They compared Ras - transformed cells with and without p53 and observed that those expressing p53 were less invasive and formed fewer focal adhesions, the molecular linkages that connect the structural scaffolding within the cell to the extracellular matrix that surrounds the cell.

Tumor cells expressing p53 (left) have fewer focal adhesions (red) and lower levels of active p130Cas (green)-- rendering them noninvasive — compared with p53 - deficient tumor cells (right).

In the current study, Dr. Rudnicki and his team discovered that muscle stem cells also express the dystrophin protein, and without this protein, they produce ten-fold fewer muscle precursor cells, which in - turn generate fewer functional muscle fibres.

We first considered that this could be an experimental artifact, since it is common for developmental genes to be expressed only in a few specific cells, which could lead to the signals from the marks being diluted out and not detected.

Since murine NSCs already express high levels of Sox2 [14]--[16], it was tested whether these cells could be reprogrammed into iPS cells by only a few critical factors.

At one end of the hierarchy are stem cells expressing most pluripotency genes studied and few lineage specific genes; at the other end are fully committed cells that have extinguished the pluripotency program, and in between there is a continuous spectrum.

Conversely, few pro-apoptotic genes are expressed in ES cells (day 0; most boxes appear in green), but many are gradually induced during the differentiation process showing the exact opposite pattern from the genes involved in cell proliferation (Figure 7).

(D) In unc - 9 daf - 6 unc - 7 animals, Pacr - 5:: unc - 9:: gfp is expressed more diffusely in cell bodies (few bright puncta).

Our collaborative effort revealed that the breast cancer stem cells expressed far fewer microRNAs than their more differentiated counterparts.