Sentences with phrase «cells expressing light»
When T cells expressing LIGHT were introduced into the mice, lipid levels rose, both when the mice were fed a regular diet, and also when fed a high - fat, high - cholesterol diet.
http://www.uchospitals.edu/ Not exact matches
Since genes for the T - cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B - cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.
A machine that detects the fluorescing light then separates out the ALPL - expressing cells.
In order to visualize this signal, the scientists performed experiments with transgenic Arabidopsis plants which were genetically modified to express a protein in the cytosol, the liquid inside the cells, which breaks down and releases light energy after it has bound calcium ions.
Expressed in the membrane separating the cell from the outside, the neuron responded to blue light with excitation.
When this clone was inserted into a mammalian expression vector and transfected into COS - 7 cells, a protein that specifically phosphorylated the agonist - occupied form of the beta 2 - adrenergic receptor and phosphorylated, much more weakly, the light - bleached form of rhodopsin was expressed.
The light sensitivity has recently been found to be due to pigments called opsins, expressed in cells close to the animal's nerve net.
Samantha de Silva and colleagues used a viral vector to express a light sensitive protein, melanopsin, in the residual retinal cells in mice which were blind from retinitis pigmentosa, the most common cause of blindness in young people.
They bred mice to express light - sensitive proteins in their acid - sensing TRCs, which make the cells fire in response to light from a laser.
One of the eight cells can express one of two different light sensitive pigments.
Many cells lit up, and when the researchers took a closer look, they found that L1 jumped into several genes typically expressed by neurons.
The researchers saw that in early stages, two days after the mice were born, developing rod cells expressed genes normally seen in mature short - wavelength cones (which are used in other animals to detect ultraviolet light).
But a team of Swiss scientists has engineered cells that come pretty close: Only when they are bathed in blue light do the cells express a gene that has been inserted into them.
Optogenetics involves expressing a light - sensitive protein in specifically targeted brain cells.
To optically manipulate specific connections to these engram cells, a blue light - sensitive protein oChIEF was expressed in an upstream brain region, i.e., medial entorhinal cortical inputs (red) to the DG.
When transplanted to the subretinal space of mice lacking functional photoreceptors, human embryonic stem cells directed toward a retinal lineage integrate into the outer nuclear layer, express photoreceptor markers, and restore a light response as determined by the electroretinogram (ERG)[5].
However, when forced to express the eye field transcription factor (EFTF) genes, the cells differentiate into all seven retinal cell classes and eventually organize themselves into a functioning eye that can detect light and guide tadpoles in a vision - based behavior.
Friedrich Miescher Institute scientists Botond Roska and Volker Busskamp have previously shown that some vision can be restored in mice by engineering those cone cells to express light - sensitive proteins.
Instead, they discovered that each V. carteri cell type expresses orthologs of genes from different temporal phases of the light — dark cycle in a related unicellular alga, Chlamydomonas reinhardtii, with somatic cells enriched for expression of dark - phase genes, and gonidial cells enriched for expression of light - phase genes.
cell type expresses orthologs of genes from different temporal phases of the light — dark cycle in a related unicellular alga,
The most compelling argument for an inflammatory role has come from studies of transgenic mice that over express LIGHT in the T cell lineage.
LIGHT can bind LTβR, a TNFR family molecule constitutively expressed on stromal cells, dendritic cells, macrophages, and some epithelial cells.
We depict an early PrEn precursor cell defined by the V+S + phenotype in light yellow, expressing low levels of PrEn determinants such as Hex and Gata6.
Several cells express the GFP, fluorescing in green, when excited with blue light.
Because Syk is expressed in many kinds of hematopoietic lineage cells and involved in various ITAM - mediated signal transduction pathways (45), our current finding that RhoH facilitates Syk activation will shed new light on ITAM - based immune responses.
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