Sentences with phrase «cells expressing neural»

We only found cells expressing neural markers within the central zone, where many cells were negative for both pluripotency and lineage specific markers.

Not exact matches

Each cell expresses a different color, allowing researchers to trace connections in the fish's neural network.

The LPA receptor is expressed in the brain of human fetuses, just as in mice, and in the same types of neural progenitor cells.

The group employed various viral tracing methods — infecting receptor - expressing neurons with a virus strain and watching them spread as they label infected cells with a fluorescent protein — to visualize the neural circuit downstream of the ESP1 receptor, as well as providing an image of nerve fibers belonging to specific neurons in the brain and synapses relaying impulses from neuron to neuron, to map the anatomical foundation that conveys ESP1 signals in the brain.

Ron McKay and his colleagues at the National Institute of Neurological Disease and Stroke in Bethesda, Maryland, usually focus on brain development, but they were intrigued by recent papers reporting that some pancreas cells express nestin, a protein typical of developing neural cells.

The genes are likely to be expressed when cells differentiate into neural crest lineages, such as neurons or Schwann cells, thereby enabling researchers to study the disease in a dish.

To devise a potential new therapy, the investigators engineered a population of neural stem cells to express a potent version of a gene called TRAIL, which codes for a molecule that activates cell - death - inducing receptors found only on the surface of cancer cells.

While both eye fields and EFTF - expressing pluripotent cells generated epidermis, forebrain, and olfactory tissue when grafted to the anterior neural plate, transplanted eye fields also formed muscle and head mesenchyme (Figure 4 and unpublished data).

Therefore, we used microarray analysis to perform pairwise comparisons of the transcriptional profile of EFTF - expressing pluripotent cells to three regions of the Xenopus embryo: the eye field (EF) including underlying mesendoderm, posterior neural plate (PNP) and the non-neural, flank, lateral endoderm (LE, Figure 1A).

Conversely, EFTF - expressing pluripotent cells (and transplanted eye fields) remained in the anterior neural plate.

They formed tiny spheres — often called tumor spheres — and expressed proteins typically found in immature neural progenitor cells.

By using the nanocomplex in conjunction with computer programme codes and imaging software, the researchers were able to follow how mRNA expresses itself during neural stem cell differentiation.

In chick embryos, skeletal muscle formation is initiated by migrating Delta1 - expressing neural crest cells that trigger NOTCH signaling and myogenesis in selected epithelial somite progenitor cells, which rapidly translocate into the nascent muscle to differentiate.

Vascular endothelial growth factor (VEGF) expressed by neural progenitor cells (NPCs)(cyan) stimulates the growth of blood vessels (red) in the mouse embryonic hindbrain, and provides regulatory factors to promote the self - renewal of neural progenitors.

We believe that a similar early precursor may exist to the PrEc lineage (Figure 9), and while we have no direct evidence for this, we did observe Oct4 positive cells that neither expressed Nanog nor the Venus transgene and there also appears a slight enrichment of early neural markers in the V − S + population (Figure 4).

On the other hand, ES cells and cells differentiating into endoderm and mesoderm lineages from ES cells express OCT - 4 in mice and humans [66], and SSEA1 expression is found in other type of cells including neural stem cells and mesenchymal stem cells [67], [68].

This image from a confocal microscope shows neural stem cells (green) in the mouse hippocampus that are actively proliferating because they express Ki67 (red), a protein that is only present in proliferating cells.

In addition, a functional BBB is manifested by a number of permanently active transport mechanisms, specifically expressed by brain capillary endothelial cells that ensure the transport of nutrients into the CNS and exclusion of blood - borne molecules that could be detrimental to the milieu required for neural transmission.