Sentences with phrase «cells form larger»

In a report published in Development, they describe early abnormalities in the way Huntington's neurons look, and how these cells form larger structures that had not previously been associated with the disease.

It is the central problem of biological evolution in which groups of cells form larger and larger organizations by generating hierarchical constraints on subgroups.

Not exact matches

We anticipate some sort of growth toward increased complexity: increasingly larger organic macromolecules, then the convergence of many macromolecules to constitute a simple living system, either as a cell with its protective wall and vital nucleus or as some functional analogue, then the convergence of many cells to form larger organisms.

In experiments on cell cultures, both of these inhibitors succeeded in breaking various forms of the TKI resistance: including forms caused by additional mutations of the gene Bcr - Abl as well as those caused by large quantities of the protein Gab2.

Diffuse large B - cell lymphoma, or DLBCL for short, is the most common form of non-Hodgkin lymphoma, and can advance very quickly.

«When we looked at the cells under the microscope, we saw neratinib, but not afatinib, causing large vesicles to form next to the cell's outer membrane.

Around the time of birth these germ cells have formed a large reserve of primordial follicles — each containing a single immature egg.

They noticed that while the dermal papilla cells from mice naturally formed large clumps in culture, the human cells didn't.

The DNA which carries genetic information in cells is normally packaged in the form of one or more large macromolecules called chromosomes.

In order to reduce these large energy losses and raise efficiency, Professor Kita's research team used two small photons from the energy transmitted through a single - junction solar cell containing a hetero - interface formed from semiconductors with different bandgaps.

«The DNA - bending module of the SRY protein is preserved among a large family of regulatory proteins that regulate key events in development, including how stem cells form the brain and other organs,» said Weiss, also a Distinguished Research Professor within the medical school.

Wilson says the team next plans to investigate if lithium chloride can blunt other forms of neurological damage, such as that resulting from trauma and stroke, both of which can kill large groups of brain cells.

For example, a drug called ibrutinib has been tested in clinical trials to treat an aggressive form of non-Hodgkin lymphoma, diffuse large B - cell lymphoma (DLBCL).

The build - up of extra cells forms patches of red, itchy skin that are covered with silvery scales and can range from a few spots to major flare - ups that cover large swathes of skin.

LEDs have been used widely for decades in other applications — forming the numbers on digital clocks, lighting up watches and cell phones and, when used in clusters, illuminating traffic lights and forming the images on large outdoor television screens.

His team had just figured out that the telescope they had built so far could form a cell of a much, much larger telescope.

This distributed biological memory leverages the large number of cells in bacterial cultures and encodes information into their collective genomic DNA in the form of the fraction of cells that carry specific mutations.

The chemical is non-toxic in larger form, but has been found to have a more harmful effect on cells on the nanoscale.

But when you analyze your brain, you will find inside it a set of nerve cells that form a large complex: one that can distinguish among a large repertoire of states in a way that its parts can not; and one that does so maximally, more than any other set of nerve cells, more than the entire body, than any crowd of men, than the world itself.»

LONDON — Wellcome Trust, the United Kingdom's largest biomedical research charity, today announced more than # 4 million in support for a pioneering, and potentially controversial, IVF treatment that could prevent some forms of muscular dystrophy and other diseases caused by defective mitochondria, the energy - generating organelle in cells.

Developing therapeutic cell populations from human ES cells will be far more demanding: cells will have to be stable, predictable, pure, have proven functionality, be nontumor - forming, and be «scalable» — capable of growing in very large numbers.

The guts of these animals produce a natural antifreeze — glycoproteins that bind to ice crystals as they begin to form and prevent them from growing large enough to fatally rupture the walls of cells.

This accelerated early development meant that blastocysts from overweight and obese women contained fewer cells, most notably in the outermost layer, which goes on to form a large part of the placenta.

These form the largest group of receptors through which hormones and neurotransmitters exert their functions on our cells, and are of highest importance as drug targets.

In particular, they are interested in the tendency of ADAR to form large multipart protein complexes, and in the exact role these complexes play in the biology of the cell.

The tendency of cells to adhere to one another and form large clusters is likely to fall under selection based on the size of resource patches in a given environment.

Because stem cells were found in the endometrium, researchers thought it likely that stem cells could also be found in the shed endometrium in the form of menstrual blood, which can be obtained in relatively large quantities in a much less invasive manner.

The proteins began to form large clusters, and the cell began to die.

The team then selected cells from these organoids and placed them inside the Intestine - Chips, which are about the size of AA batteries and re-create the natural microenvironment of the human intestine, including the intestinal epithelium — the layer of cells that forms the lining of both the small and large intestines.

Anaplastic large cell lymphoma (ALCL) is an aggressive form of malignant lymphoma of T / null lineage (1).

By collecting and banking your stem cells — especially while you are healthy — you are collecting a large number of stem cells and an array of differentiated cell lines, including the ones committed to form immune cells.

Four of the proteins Sondheimer studied formed clumps in cells, which appeared as large green fluorescent dots.

Rothman also proposed that SNAP - 25, VAMP / synaptobrevin and syntaxin represent members of a large family of proteins, different forms of which are involved in membrane fusion in all cells, and in different compartments within cells.

The iPSC colonies were morphologically indistinguishable from hESCs, forming tight colonies of cells with a large nucleus to cytoplasm ratio and prominent nucleoli (Fig. 2E), and they did not display the NSCs» original cell morphology (Fig. 2F).

In biological systems, the nanoscale catalytic materials attach to larger entities such as proteins and cells, which self - organize to form larger networks of precisely designed catalytic sites.

Adoptive Cell Transfer (ACT) is a form of immunotherapy that targets tumors specifically and potently by utilizing large numbers of a patient's own immune cells to target and destroy cancer cells.

Among its other roles, SIRT6 plays a large part in cell division and, as Mostoslavsky has found, the maturation of embryonic stem cells into their adult forms.

While cautioning that the new radiation delivery system is still far from ready for use in people, Abraham notes that P32 gives off high energy that can penetrate through 5 millimeters of human tissue, making it a good candidate to tackle colon cancer since colon cancer cells can often form large, thick tumors into which drugs may not penetrate very well.

We observed that all three biological replicates with the transduced SSEA3 - negative cells formed many large background colonies (10 — 27 per replicate, Figure 4A) but no iPSC colonies emerged; in contrast, all three biological replicates with the transduced SSEA3 - positive cells resulted in the formation of iPSC colonies (4 — 5 per replicate, Figure 4B) but very few large background colonies (0 — 1 per replicate, Table 1).

A range of research groups are picking away at individual forms of waste, some with large amounts of funding, some with very little funding, but this is a similar situation to that I outlined above for stem cell aging.

It might be possible in the near future to use one of the new forms of genetic technology to tackle the clonal expansions of specific mutations, provided there are only a few of them and they are present in large numbers of cells.

The Consortium for Functional Glycomics (CFG) is a large research initiative, funded by the National Institute of General Medical Sciences, and formed to define the paradigms by which protein - carbohydrate interactions mediate cell communication.

But this model does not explain how many of our organs — which develop relatively late, when the embryo is large — are furnished with cells that form the parasympathetic neurons.

So a stage four diffuse large B - cell lymphoma which is a form of non-Hodgkin lymphoma.

As we already know, starch is a complex carbohydrate in the form of many small molecules that are attached to each other in large chains, which get broken down into smaller ones once they are digested for the purpose of meeting the energy needs of all cells in our bodies.

The fatty plaques attract white blood cells, grow larger, and can form blood clots, which can cause a heart attack.

Maintaining the integrity of the gut is a one - cell - thick barrier that forms a tight junction, which keeps out foreign invaders like bacteria, toxins, and large undigested food particles.

Persistent inflammation induced by prolonged or repetitive exposure to specific allergens, typically characterized not only by the presence of large numbers of innate and adaptive immune cells (in the form of leukocytes) at the affected site but also by substantial changes in the extracellular matrix and alterations in the number, phenotype and function of structural cells in the affected tissues.

1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones and teeth

Smaller «between» cells called desmosomes join adjacent cells together to form a strong, sturdy structure, which prevents large molecules from passing through.