Sentences with phrase «cells form tumors»

Colon and rectal cancers (CRC) occur when abnormal cells form tumors in the tissues of those body parts.

Plasma cell neoplasms are diseases in which abnormal plasma cells or myeloma cells form tumors in the bones or soft tissues of the body.

Furthermore, when injected into live animals, these aberrant cells form tumors.

Biology professor David Soll and his team used unique computer - assisted 3 - D reconstruction software to chronicle how both breast tissue cancer cells and melanoma cells form tumors.

Researchers at the University of Iowa did just that, documenting in real time and in 3 - D how melanoma cells form tumors.

Can any cancer cell form another tumor, or is it only select cancer stem cells that give rise to new cancer cells?

The cells formed tumors that grew to a diameter of one - fifth of an inch or more.

Those cells form a tumor.

The accumulating abnormal thyroid cells form a tumor.

Not exact matches

CAR - T cell therapy is a form of immunotherapy, a rapidly developing cancer treatment that uses patients» own immune cells to attack tumors.

These antioxidants are partly responsible for halting DNA damage, which means cancerous cells can not mutate and form tumors.

Renal cell carcinoma, also known by the eponym Grawitz tumor, is the most common form of kidney cancer arising from the renal tubule.

Similarly, when these cells were injected into mice, the cells in which SLC13A5 was suppressed formed barely discernable tumors compared to the unmanipulated cancer cells.

In the upper panel, tumor cells formed colonization at day 14, while in the lower panel, when the mouse was treated with the compound edelfosine, most of the tumor cells disappeared at day 10 and failed to form colonization at day 14.

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis.

Previous work in Weinberg's lab had shown that after a tumor forms in one part of the body, some of the cancer cells undergo EMT, Mani explains.

Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma (iCCA), the second most common form of liver cancer, according to a research published in the July issue of the journal Nature.

Dr. Llovet and colleagues demonstrated that the expression of mutant IDH in the adult liver of genetically engineered mice impairs liver cell development and liver regeneration — a process in which the liver responds to injury — and increases the number of cells to form a tumor.

Bowel cancer, also called colorectal cancer, results from a series of genetic changes (mutations) that cause healthy cells to become progressively cancerous, first forming early tumors called polyps that can eventually become malignant.

Conventional, high - dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors» recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered.

These cells quickly divide and grow, eventually forming a mass, or tumor.

A study analyzing brain tumor genomics on a single - cell level has found evidence that cancer stem cells fuel the growth of oligodendrogliomas, a slow - growing but incurable form of brain cancer.

With that knowledge, they screened more than four dozen monoclonal antibodies — unique agents that can stop cells from growing or forming tumors and can be mass produced — before finding two that block tumor creation in both types of cancer.

The cells waste no time finding their cancerous cousins, slashing their way through a lab - prepared gel to quickly join other melanoma cells and form tumors.

Melanoma cells move quickly, extending cables to reel in other cells and form tumors.

«What our findings show is that the problems with iPS cells don't just involve one or two or a few abnormal iPS cells escaping into the body and forming tumors, but that the whole population of cells is screwed up,» Lanza says.

Researchers are also experimenting with another form of immunotherapy called adoptive cell transfer, which harvests and then reintroduces patients» tumor - infiltrating lymphocytes — cells with anti-tumor capabilities that dig deep behind enemy lines.

The researchers demonstrated that blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect on normal cells or peritoneal pancreatic cancer controls.

Maria Zajac - Kaye, Ph.D., an associate professor in the College of Medicine's department of anatomy and cell biology, and Rony François, an M.D. / Ph.D. student who works with her, found a new drug combination that inhibits one form of pancreatic cancer tumor and kills its cells.

One form of pancreatic cancer has a new enemy: a two - drug combination discovered by UF Health researchers that inhibits tumors and kills cancer cells in mouse models.

Metastatic cancer cells have the ability to break free from tissue, circulate in the blood stream, and form tumors all over the body, in a way acting like blood cells.

Dr. Cripe and his colleagues at The Ohio State University, the University of Pittsburgh School of Medicine and Cincinnati Children's Hospital Medical Center tested how well the oncolytic viral therapy — a cancer - killing form of the herpes simplex virus, called oHSV — infected and killed tumor cells in mice with and without a healthy immune system.

The initial experiments made use of cancer cells that Quiñones - Hinojosa and his team removed from willing patients and grew in the laboratory until they formed little spheres of cells, termed oncospheres, likely to be the most resistant to chemotherapy and radiation, and capable of creating new tumors.

When cancer cells start dividing rapidly to form tumors, these cells are actually reverting to an earlier time in their development when they were supposed to divide rapidly.

This forms a structured and strong vessel barrier around the tumor, preventing cancer cells to escape to the bloodstream and invade distant organs.»

«Indeed, when we studied the mice at the embryonic stage, we saw the cells between the muscle fibers expanded explosively and formed tumors early in development,» Hatley said.

It is well established that melanoma cells can spread through the blood to accumulate and form new tumors (metastases) in other parts of the body away from the original tumor.

Pathologists classify tumors by how far their cells deviate from their normal forms, while hematologists identify and count different leukocytes by sight.

Glioblastoma is the most lethal form of primary brain tumor and leads to death in patients by invading the brain tissue in a process that allows single cells to move through normal brain tissue, which makes complete surgical removal of the tumor impossible.

Some scientists have blamed so - called cancer stem cells, a subset of cancer cells that might be able to remain dormant, evading chemotherapy or radiation treatments, only to form new tumors months or years later.

Aware that cancers rewire their metabolism in ways that could change the epigenome and that distant metastases in pancreatic cancer naturally spread to organs fed by a sugar - rich blood supply, the researchers wondered if the tumor cells had altered the way they use the basic form of sugar, glucose.

Three of the four projects receiving CIRM money capitalize on Victoria's expertise at finding markers for differentiated stem cells versus cells that still have tumor - forming potential.

Olaparib had no effect on tumors formed by breast cancer cells containing functional BRCA1 and BRCA2 genes.

Northwestern University scientists now have demonstrated a simple but powerful tool that can detect live cancer cells in the bloodstream, potentially long before the cells could settle somewhere in the body and form a dangerous tumor.

In tumors formed by human breast cancer cells, DNA damage (brown staining) is increased by simultaneous Olaparib treatment and PGAM1 suppression (right) when compared to either Olaparib treatment (left) or PGAM1 suppression (center) alone.

In this study, the researchers tested the effects of Olaparib on the tumors formed by human breast cancer cells injected into mice.

«Dormant disseminated tumors can be ticking time bombs, but now that we know some of the triggers, it may be possible to develop therapies to ensure that disseminated cancer cells remain in a dormant state, or other therapies that eradicate these cells before they form full - blown metastases.»

By using molecular genetic tools to reduce the amount of PC in human lung cancer cells, the team observed decreased cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically used to grow bacteria and other cells), and a reduced rate of tumor growth in mice.

This meant they were able to remove very immature (undifferentiated) cells that could form tumors.

«Some cells that we call cancer stem cells adopt deadly characteristics where they can travel through the bloodstream to other tissue and form new tumors.