Not exact matches
Cancer
cells can break away
from a primary tumor, penetrate into lymphatic and
blood vessels,
circulate through the bloodstream, and grow in a distant focus (metastasize) in normal tissues elsewhere in the body.
Six months later,
blood cells from both the donor and host were still
circulating around the body.
These techniques include: human tissue created by reprogramming
cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a
circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.
A dense layer of
cells called the
blood - brain barrier protects the organ
from germs
circulating in the body, and
from the immune
cells that combat them.
Metastatic cancer
cells have the ability to break free
from tissue,
circulate in the
blood stream, and form tumors all over the body, in a way acting like
blood cells.
Now a team of researchers in China has developed a new microfluidic chip that can quickly and efficiently segregate and capture live
circulating tumor
cells (CTCs)
from a patient's
blood, with potential applications for cancer screenings and treatment assessments.
Moreover, a substantial increase in
circulating endothelial progenitor
cells, which repair damaged
blood vessels, was noted after consuming bread made
from the ancient grain Verna.
«This development has the potential to enable earlier detection of solid tumors through a simple
blood draw by substantially improving our ability to detect very low quantities of
circulating DNA derived
from tumor
cells,» says corresponding author Hunter Underhill, M.D., Ph.D., who initiated the research while in the lab of senior author Jay Shendure, M.D., Ph.D., a professor in genome sciences at the University of Washington.
DDRs inhibition with a tyrosine kinase inhibitor appears to insulate the brain via
blood - brain barrier repair, which prevents harmful immune
cells that
circulate in the body
from getting into the brain where they can indiscriminately attack and kill healthy and sick neurons, like those that have been unable to perform autophagy to «take out their trash,» says Moussa.
Earlier mouse studies by Li and his collaborators had indicated that the expression of several imprinted genes changes as hematopoietic stem
cells embark on their journey
from quiescent reserve
cells to multi-lineage progenitor
cells, which form the many highly specialized
cell types that
circulate within the
blood stream.
«Our
circulating tumor
cell device can release a tumor
cell captured
from a
blood sample, enabling single
cell analysis,» says Liu.
The first stage of the trial, which involved an analysis of
circulating tumor
cells from a single
blood draw of several dozen patients, has demonstrated strong potential.
Adds Liu: «With metastatic cancers accounting for around 90 % of deaths
from solid tumors, the hope is that one day a device that can enable the analysis of single tumor
cells circulating in the
blood could make a big difference in early diagnosis, detection and monitoring of numerous types of cancer, without invasive biopsies.»
By inducing
cells that line the capillaries to keep a tight seal, astrocytes maintain the
blood - brain barrier, which protects the brain
from many
circulating molecules.
An impermeable shield of endothelial
cells that protects our brains
from toxins and other threats that may lurk in
circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.
Once thought to be confined to
cells in the womb, its sequence can now be reconstructed
from segments
circulating in the mother's
blood.
How the placenta passes nutrients
from mother to fetus depends in part on the activity of insulin — a
circulating hormone that tells fat and muscle
cells to absorb glucose and other nutrients
from the
blood.
T
cells, which
circulate in the
blood, are an obvious candidate for medical applications of the technology, as these
cells not only stand at the center of many disease processes, but could be easily gathered
from patients, edited with CRISPR / Cas9, then returned to the body to exert therapeutic effects.
Berkeley researchers isolated
circulating tumor
cells from the
blood of breast cancer patients, then used microscale physics to design a precision test for protein biomarkers, which are indicators of cancer.
So my field is science and technology, so my work is
circulating tumor
cells where I isolate cancer
cells from blood of patients and isolate their DNA and RNA and try to sequence them and try to device treatments for cancer treatment and therapy.
These
cells are thought to break off
from the original tumor and
circulate in the
blood, and may be a sign of an aggressive tumor.
In response to this damage, immune
cells residing in the liver are activated, especially macrophages, and additional immune
cells are recruited
from the
circulating blood.
That allowed each nanoparticle, packed with medication, to
circulate in the
blood in a surrounding cloud of water that shielded it
from immune
cells.
The DNA
from cancer
cells is mutated and this mutated DNA can get into the
blood stream (
circulating tumour DNA, ctDNA) and be detected by sequencing the DNA in
blood.
These
cells circulate throughout the body and can be readily obtained
from a
blood sample.
The way in which they did this was by isolating
circulating tumor
cells from a drawing of
blood.
We have invented new biomaterial surfaces based on natural halloysite nanotubes, that capture rare
circulating tumor
cells (CTCs)
from blood while simultaneously repelling white
blood cells.
And while the human and T
cells they studied in the laboratory were not specifically skin T
cells they were isolated
from mouse
cell culture and
from human
blood — the skin has a large share of T
cells in humans, he says, approximately twice the number
circulating in the
blood.
The HDL is released
from the liver and
circulates in the
blood picking up cholesterol and phospholipids
from body
cells and returning them to the liver to be removed
from the body.
Greece Test
Circulating Tumor Cells are cells that have been released from a tumor and are circulating in the bl
Circulating Tumor
Cells are cells that have been released from a tumor and are circulating in the blood st
Cells are
cells that have been released from a tumor and are circulating in the blood st
cells that have been released
from a tumor and are
circulating in the bl
circulating in the
blood stream.
As
blood circulates in the capillaries around our salivary glands, some of the free / unbound steroid hormones disconnect
from the
blood cells and bind themselves to
cell receptors within the salivary glands.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or
blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (
blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band
cell — type of white
blood cell Baso basophil — type of white
blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice
from liver disease or RBC destruction) BP -
blood pressure measurement BUN -
blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete
blood count (all
circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration,
blood pH) CO2 - carbon dioxide (
blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red
blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (
blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white
blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu
blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white
blood cells Hb, Hgb hemoglobin — iron rich protein bound to red
blood cells that carries oxygen (anemia, red
cell mass) HCO3 - bicarbonate ion (
blood pH) HCT, PCV, MHCT hematocrit, packed -
cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white
blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red
cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed -
cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white
blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red
blood cell — immature red
blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed -
cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet —
cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red
blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red
blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white
blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white
blood cell count (infection, inflammation, bone marrow suppression)
The number of
circulating red
blood cells may become reduced if there is a decrease in production of them in the bone marrow, or if there is an increased loss of them
from the circulation.