Last week British scientists announced that they had created sperm
cells from embryonic stem cells for the first time.
Researchers find that Insulin - like growth factor / Insulin - mediated induction of mesodermal differentiation aids the production of cardiac progenitor
cells from embryonic stem cells towards a strategy to boost cardiac cell production.
To explore this question, they generated neural
cells from embryonic stem cells and then removed DNMT3A from the cellular environment.
In addition, we use our expertise to facilitate the development of functionally mature beta
cells from embryonic stem cells for cell replacement therapies of type 1 diabetes.
Improved production of retinal
cells from embryonic stem cells brings this therapy closer to the clinic.
For the purpose of additional experiments, the researchers generated myocardial
cells from embryonic stem cells and human skin cells, in collaboration with the lab headed by Prof Dr Jürgen Hescheler at the University of Cologne.
Not exact matches
James Thomson of the University of Wisconsin and Shinya Yamanaka of Kyoto, Japan, discovered a way to produce
embryonic stem cells directly
from adult
cells.
Two new papers have just been published documenting further advances with induced pluripotent
stem cells ---
stem cells that are «
embryonic - like» but that are not derived
from embryos.
Scientists looking for new methods to make human tissue have successfully used cloning technology to create
embryonic stem cells from skin
cells.
Not surprisingly, President Obama received high marks
from the journal, largely because his response to the question of whether he would lift Bush's ban on the federal funding of new
embryonic stem -
cell lines is in line with the view of most in the scientific community.
The National Institutes of Health (NIH) has allowed a contract for the dissemination of
embryonic stem cell lines approved for US government funding to lapse, shuttering a key
stem cell bank, and doubling the price researchers pay for samples of some human
embryonic stem cell (hESC) line...
from $ 500 per vial of frozen
cells to $ 1,000.
Well it seems like Ivan can relax, Michael Peroski has just solved all of our problems: Proceeding
from ideology - driven inquiry entails starting
from an answer: «Research on human
embryonic stem cell should be forbidden because embryos are equivalent to human lives» and working....
A very significant step away
from embryonic stem -
cell research was taken recently when a previously forthright advocate of such research softened his stance on other ethical alternatives.
On his website he writes: «
Embryonic stem (ES)
cells are pluripotent
stem cells derived
from inner
cell mass of mammalian blastocysts.
In 2005, before a Congressional hearing in the U.S., Prof. George Q. Daley of Harvard spoke forcefully and influentially about the necessity for
embryonic stem -
cell research to go ahead, and dismissed suggestions that one could work instead with «induced pluripotent
stem cells» («iPS», i.e.
stem cells reprogrammed
from some
cells of a living adult).
Less incredible, and perhaps only to be expected, is the news that Peter Jackson and Fran Walsh, the dynamic duo who brought The Lord of the Rings to the silver screen, have donated $ 310,000
from the movie's profits to fund human
embryonic stem -
cell research.
(In many ways it is worse than when John Edwards said in 2004 that if people voted for John Kerry, people like Christopher Reeve would get out of their wheelchairs and walk
from embryonic stem cell therapies.)
A pluripotent state makes the resulting
cells indistinguishable
from embryonic stem cells, and the scientists got these
cells without creating or destroying any embryos.
For example, ten or twenty years
from now, the physician's tools may include
embryonic stem cells or products obtained
from cloned embryos and fetuses gestated for that purpose, making physicians who provide such treatments complicit in the life destruction required to obtain the modalities.
While scientists have previously had success in 3D printing a range of human
stem cell cultures developed
from bone marrow or skin
cells, a team
from Scotland's Heriot - Watt University claims to be the first to print the more delicate, yet more flexible, human
embryonic stem cells (hESCs).
Peter Tatchell, human rights campaigner, talked about Catholic dissent
from the Pope's hardline, intolerant opposition to liberation theology, women's rights, gay equality, contraception, fertility treatment,
embryonic stem cell research and the Pope's collusion with Holocaust deniers and appeasers.
From the
embryonic stem cells, the researchers produced a type of tissue called retinal pigment epithelium (RPE).
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human
embryonic kidney
cells, brain
cell samples and neurons derived
from the
stem cells of healthy people and those with spinal muscular atrophy type I and II.
Da Cruz and his team grew replacement RPE
cells from human
embryonic stem cells on a thin plastic scaffold, before transplanting the tissue into the back of each volunteer's eye.
Two people with severe sight loss can now see well enough to read after receiving tissue grown
from human
embryonic stem cells.
Human
embryonic stem cells typically come
from fertilized eggs.
Trials of
cells made
from human
embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time
embryonic stem cells have been used in the treatment of major lethal diseases.
The researchers say that they can grow the stomach organoids
from both
embryonic stem cells and skin
cells induced to pluripotency.
Some scientists had claimed that the lymphatic system was derived
from specialized
stem cells called angioblasts, whereas others had argued that it originated by the differentiation of pre-existing
embryonic veins.
Faced with an often - hostile Congress, Obama enacted many of his signature policies by executive order —
from reversing restrictions on research with human
embryonic stem cells to helping communities prepare for climate change.
For example, a consortium of research groups called the London Project to Cure Blindness aims to test RPE transplants
from embryonic stem cells in patients with macular degeneration this year.
Oliver Brüstle, director of the Institute of Reconstructive Neurobiology at the University of Bonn, Germany, who had a patent on a method for generating neurons
from human
embryonic stem cells rejected by the court, called the ruling «the worst possible outcome», and «a disaster for Europe».
Advanced
Cell Technology, based in Santa Monica California, is developing embryonic stem cell therapies for macular degeneration and other conditions using cells obtained non-destructively from an early embryo called a blastoc
Cell Technology, based in Santa Monica California, is developing
embryonic stem cell therapies for macular degeneration and other conditions using cells obtained non-destructively from an early embryo called a blastoc
cell therapies for macular degeneration and other conditions using
cells obtained non-destructively
from an early embryo called a blastocyst.
Researchers at Geron, meanwhile, had successfully derived neurons
from human
embryonic stem cells and were pursuing research that would eventually look to repair the damage caused by spinal - cord injuries, a possible use for
embryonic stem cells that was much touted at the time.
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes
from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human
cell types, including normal and cancerous colon, lung and liver
cells, as well as brain, skin, blood and
embryonic stem cells.
«We've figured out for the first time how to produce these
cells from human
embryonic stem cells literally by the billions and billions,» Lanza says.
But the factor that may make the discovery very significant is that umbilical cord blood can be saved, stored and multiplied without any of the ethical dilemmas facing
embryonic stem cell use, which are derived
from human fetuses.
For example, animal studies have shown that neurons derived in the lab
from human
embryonic stem cells improve Parkinson's symptoms; however, any residual
stem cells associated with those neurons could form masses of unwanted
cells.
Consequently, a fundamental argument against using
embryonic stem cells and therapeutic cloning can not be derived
from existing constitutional law and additional court decisions.
* Note
from Next Wave's German editor: Current German law prohibits the production of
embryonic stem cells, but has a loophole that allows their import.
Embryonic - like
stem cells have been isolated
from breast milk in large numbers.
«We're now developing a new bioreactor to make considerably more, which means we can make thousands and thousands more
stem cells than are available
from embryonic sources,» says McGuckin.
Research involving the derivation and use of
embryonic stem (ES)
cells is permissible only where there is strong scientific merit in, and potential medical benefit
from, such research.
In addition, where
cells derived
from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of
cells for clinical use — ones
from the iPS lines were much feebler.
Stem cells from breast milk can grow into many other kinds of human tissue, raising hopes of an ethical source of embryonic - like stem c
Stem cells from breast milk can grow into many other kinds of human tissue, raising hopes of an ethical source of
embryonic - like
stem c
stem cells
Two weeks after the experimental myocardial infarctions, the Seattle researchers injected 1 billion heart muscle
cells derived
from human
embryonic stem cells, called human
embryonic stem cell - derived cardiomyocytes, into the infarcted muscle.
Freed expects transplants of neurons derived
from embryonic stem cells to enter the clinical arena soon as well.
Although British researchers had discovered
embryonic stem cells in laboratory animals in 1981, it wasn't until 1998 that a Wisconsin team announced it had isolated
stem cells from human embryos for the first time.
The act of reprogramming
cells to make them as capable as ones
from embryos apparently can result in aberrant
cells that age and die abnormally, suggesting there is a long way to go to prove such
cells are really like
embryonic stem cells and can find use in therapies.
Eighteen adults with severe eye disease who were among the first people to receive transplants created
from human
embryonic stem cells (hESCs) continue to have no apparent complications with the introduced
cells after an average of nearly 2 years, according to the latest status report on their health.