Sentences with phrase «cells from normal mice»

They destroyed the T cells in 12 mice, five of which received marrow cells from normal mice while seven received marrow from mice with a defective Fas - ligand gene.

When she compared the «healer» cells from the lupus mice with «nonhealer» cells from normal mice, she noticed several differences.

Not exact matches

In experiments on normal and MLL cells from mice and humans, the researchers demonstrated that beta - catenin is activated in cancer stem cells that prompt leukaemic blood cells to multiply.

When the Stanford team measured pyrophosphate levels in cultured cells derived from ank and normal mice, they found that the chemical accumulated in cells from the ank mice but decreased in the culture medium.

They expected eggs to be more complex, but last year, Hayashi made PGCs in vitro with cells from a mouse with normal coloring and then transferred them into the ovaries of an albino mouse.

In another experiment, the research team transferred infection - combatting white blood cells — called neutrophils — from normal mice to genetically mutated mice.

During her postdoctoral work, Bissell noticed that removing mammary cells from a mouse and putting them into a culture dish caused them to lose not only their normal in vivo shapes, but also their ability to secrete milk.

The scientists first compared mouse megakaryocyte cells created from embryonic stem cells engineered to lack p45 - Nfe2 with normal megakaryocytes.

Not only did the normal mice develop plaques, but also a pathology similar to «tangles» — twisted protein strands that form inside brain cells, disrupting their function and eventually killing them from the inside - out.

Mice generated from embryonic stem cells in which ion channel genes have been mutated by homologous recombination often have a perfectly normal heart.

(Left) Blood smears from anemic mice indicate irregular shapes of red blood cells; (right) wild type mice indicate normal shapes of red blood cells.

As controls, fibroblasts and secretions from normal lab rats, mice, and another rodent called the spiny mouse were powerless to stop the human cancer cells growing.

Kipnis and his colleagues wondered how smart mice would be if they had a normal supply of T cells everywhere in their bodies except the meninges, so he injected a compound into mice that prevented T cells from reaching the meninges.

This time, Xu used a sophisticated technique called droplet digital PCR to count the ribosomal DNA copies in normal and cancer cells from the mice.

Bone marrow from the p16 - deficient mice made 3 times as many blood - forming stem cells as bone marrow from the normal mice did.

Faustman got her idea by chance while transplanting islets, the pancreatic bodies that contain beta cells, from normal mice into others that had lost theirs to type 1, or juvenile, diabetes.

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses.

Experiments on mice and on heart cells obtained from infants born with congenital heart disease suggest that neuregulin 1, a human growth factor, can put infant heart cells on a path that mimics normal growth rather than stalling out.

But many in the field will be waiting for the next steps: testing whether the resulting mouse pups are genetically normal, trying out the technique in other animals, and using other and less controversial types of cells — such as stem cells that can be extracted and cryopreserved from adult testicular tissue — as the starting point.

Although muscle cells did not reduce in size or number in mice lacking a protective antioxidant protein, they were weaker than normal muscle cells, researchers from the Barshop Institute for Longevity and Aging Studies at The University of Texas Health Science Center San Antonio found.

The researchers compared mice with a normal glymphatic system to those with a disabled gene that prevented glial cells from assisting in the fluid flow.

The green - labelled cells show a basal cell carcinoma in mouse tail epidermis derived from a single mutant stem cell and expanding out of the normal epidermis stained in red.

They observed a significant decrease in the number of proliferating stem cells in the brains of HIV / gp120 - mice compared with similar tissue from normal, wild - type mice.

Mice that received normal levels of prenatal vitamin A, from a regular diet, were born with more fat - loading white fat cells, fewer brown fat cells and fewer blood vessels.

Using adoptive transfer experiments we found that spleen cells from persistently infected (carrier) mice actively suppressed the expected LCMV - specific CTL response of spleen cells from normal adult mice.

Organoids enabled the team to compare normal pancreatic ductal cells in six mice with cells from the same animals in three distinct stages: premalignant, malignant, and metastatic.

The resulting mice had normal populations of T regulatory cells from the thymus, but significantly diminished numbers of pTregs.

The present study employed Ighb scid mice reconstituted with normal lymphocytes from young (2 -3-mo-old) and aged (20 -25-mo-old) donors and immunized with a protein conjugate of the hapten (4 - hydroxy -3-nitrophenyl) acetyl (NP) to determine whether the molecular changes in antibody repertoire reflect senescence in the B cells or whether they are mediated by the aging helper T lymphocytes.

Furthermore, histological examination of the testes indicated that the morphology of seminiferous tubules from F0 IVC mice appeared normal, but some seminiferous tubules showed germ cell - deficiency.

The Barcode database provides gene expression information about thousands of mouse and human samples from different normal and cancerous cells / tissues obtained pre - or postnatally.

Cells with normal karyotype were injected into blastocysts isolated from C57BL / 6 mice.

* Oddly enough, however, the experiments with fresh pancreatic islets and fat cells taken from the mice suggested that the positive effects of uncarboxylated osteocalcin on insulin only occurred at concentrations extremely low compared to those of undercarboxylated osteocalcin normally present in mice, while the effects on adiponectin and energy expenditure only occurred at normal to high concentrations.