Sentences with phrase «cells from patients affected»

Biological and functional characterization of bone marrow - derived mesenchymal stromal cells from patients affected by primary immunodeficiency.

In the next step, we will use cells from patients affected by neuromuscular diseases.

Not exact matches

The researchers isolated bacteria from the tumors of pancreatic cancer patients and tested how they affect the sensitivity of pancreatic cancer cells to gemcitabine, a chemotherapy drug.

This study shows that the mesenchymal subtype is the most aggressive subtype, that it has the poorest prognosis among affected patients, and that cancer stem cells isolated from the mesenchymal subtype have significantly higher levels of the enzyme ALDH1A3 compared with the proneural subtype.

The two groups took skin cells from patients and transformed them into the type of brain cells that are affected by Alzheimer's.

This analysis, done on separate samples from the same patient, revealed that many of the affected genes confer advantages to cancer cells by, for example, enhancing cell migration or resistance to chemotherapy.

Belgian researchers have identified a new strategy for treating an inherited form of dementia after attempting to turn stem cells derived from patients into the neurons most affected by the disease.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

Monitoring immune cell activity — including phenotyping immune cell subsets, tracking cell proliferation, and measuring cytokine production — can provide insights into the overall status of immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from autoimmune disease or other pathologies that affect the immune system.

Researchers at MIT have now shown that they can use a new type of measurement to predict how drugs will affect cancer cells taken from multiple - myeloma patients.

Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth.

Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most aggressive type of skin cancer, as well as breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.

Although this human Gut Chip recreated the villus epithelium of normal intestine and enabled new insights into how flow and cyclic peristalsis affects intestinal differentiation and function, it could not be used to study processes that relied on normal intestinal cells from individual donors, which, for example, is crucial for studying patient - specific responses for personalized medicine.

Results of a phase one trial show that an investigational topical drug, resiquimod gel, causes regression of both treated and untreated tumor lesions and may completely remove cancerous cells from both sites in patients with early stage cutaneous T cell lymphoma (CTCL)-- a rare type of non-Hodgkin lymphoma that affects the skin.

«We used human skin cells that we obtained from patients affected with ALS and converted them into neurons via a technology called induced pluripotent stem cell production,» she explains.

A study led by scientists from Harvard Medical School reveals «hidden» variability in how tumor cells are affected by anticancer drugs, offering new insights on why patients with the same form of cancer can have different responses to a drug.

Furthermore, the generation of induced Pluripotent Stem (iPS) cells from an individual RP patient would enable the large - scale production of the cell types affected by the patient's disease.

For these purposes, we are establishing a partnership with Jamel Chelly (Cochin, Paris, France) to produce iPS cells from muscle progenitor cells of healthy subjects and patients affected by Duchenne Muscular Dystrophy.

Kaufman finished by also commenting on the implications of people affected by incurable conditions paying for treatments from stem cell clinics, that he acknowledged for the most part want to help patients.

TNGB collects, stores and distributes high quality biological materials (nucleic acids, cell lines and tissue samples) linked to relevant clinical and genetic data from patients affected by inherited diseases.

The knowledge about how this cancer form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University / SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the tumor originates as well as the age of the patient.

Stem cells allow researchers to collect blood or skin samples from living patients and turn them into the brain cells affected by the disease — neural progenitor cells (NPCs) and neurons.

Sickle cell disease affects about 100,000 Americans, and it's caused by a single genetic mutation that must be inherited from both a patient's mother and father.

As these authors from Biopharm Serfices and Biopharm Designs show, varying overall process failure rates significantly affects the per - patient cost of a dendritic cell treatment.

Conduct clinical trials in a petri dish using the actual affected human cell types — from patients rather than from surrogate models (e.g. animals).

And the good news is there are a number of treatment options available including camouflage using make - up and self tanning lotions; micro-tattooing may be useful for small stable areas of vitiligo such as face, lips and hands; light therapy; the transfer of a patient's own pigment cells from unaffected skin into the vitiligo - affected cells and laser treatments.

The study involves injecting feline patients with stem cells cultivated from the fat of young, healthy cats, and has shown promise for treating a health problem that affects approximately 50 percent of cats older than 10, CSU said.

In some instances the globulin levels become so high that blood must be drained from the affected dog, the extra proteins removed, and the red blood cells given back to the patient.