Sentences with phrase «cells from those blood samples»

Eisenberg measured telomere length in cells from those blood samples.

To find out, they studied T cells from blood samples from 71 children with dengue fever or dengue hemorrhagic fever.

In this study, researchers measured the mtDNA amount and degree of mtDNA damage in blood cells from blood samples from veterans with GWI.

The chip would allow the filtering of cancer cells from a blood sample, which would be an easier way to harvest cancer cells, rather than the current method of taking them from tumor sites in the body.

Platelet - rich plasma is obtained via a process called centrifugation that removes red and white blood cells from a blood sample while leaving behind a high concentration of platelets in the plasma.

Not exact matches

Vortex's system uses a microfluidic chip to generate tiny vortices that trap larger, more deformable cancer cells from a blood plasma sample.

In blood samples from these patients, the researchers found an increase in the percentage of gamma delta T cells, similar to what they observed in mice, which remained stable over years.

Users simply collect a blood sample from a patient, feed it into the device, and retrieve any purified tumor cells a few hours later.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

Researchers are developing many different versions of CAR - T cell therapies, but the basic premise is the same: Doctors remove a patient's T cells (immune system cells that attack invaders) from a blood sample and genetically modify them to produce artificial proteins on their surfaces.

[Chinedu Nwokoro et al., «Inhaled black carbon in the lower airways of London cyclists»] Researchers at the London School of Medicine collected sputum samples from healthy non-smokers who walk or bike to see how much black carbon was in airway macrophages — a type of white blood cell that takes in foreign material.

However, Japanese scientists led by stem - cell pioneer Shinya Yamanaka are doing exactly that, he says, creating a bank of stem cells derived from cord - blood samples from Japanese blood banks.

In their investigation, Greaves and colleagues discovered incipient cancer cells in routine blood samples taken from the child at birth, strongly suggesting that the transmission happened in utero.

Current genome sequencing techniques involve the chemical disintegration of samples of red blood cells from infected patients to obtain parasite DNA, which are then sequenced.

They checked that the viral gene fragments in the child and mother were a close match, and double - checked that the samples of blood cells from the child were his and no one else's, by matching them genetically with the mother.

New markers suggested include total mass of hemoglobin, altered expression of genes related to red blood cell metabolism, ironomics, storage lesions, and the presence of plasticizers from blood bags in athlete urine samples.

Over the course of three years, Horvath and his team analyzed nearly 8,000 tissue samples from these datasets, which included blood, saliva and cells from organs like the brain and the colon.

Schiffman and his team conducted another series of experiments in the laboratory on blood samples from adult African elephants to find how these genes respond to DNA damage in the elephant cells.

By varying the compositions of lipids, cues, and diffusible factors in the scaffolds, we engineered a very versatile and flexible platform that can be used to amplify specific T cell populations from blood samples, and that could be deployed in existing therapies such as CAR - T cell therapies,» said Mooney, Ph.D., a Core Faculty member at the Wyss Institute and leader of its Immunomaterials Platform.

But about 20 years ago, researchers started noticing that the levels of cytokines and T - cells, which help drive immune responses and secrete cytokines, were higher instead of lower in blood samples from people diagnosed with depression.

The team used a statistical model of T cell receptor formation to analyze receptor DNA sequences in blood samples from adult pairs of identical twins.

Cheng, an assistant professor of medicine in hematology / oncology at Feinberg, provided the cell lines and NanoFlare targets the researchers used to model blood samples taken from breast cancer patients.

In a comprehensive and complex molecular study of blood samples from Ebola patients in Sierra Leone, published in Cell Host and Microbe, a scientific team led by the University of Wisconsin - Madison has identified signatures of Ebola virus disease that may aid in future treatment efforts.

After 3 months, the researchers drew blood samples from the monkeys, purified five different types of immune cells, and measured gene expression across their entire genomes.

«Our circulating tumor cell device can release a tumor cell captured from a blood sample, enabling single cell analysis,» says Liu.

CEPH's idea was to develop a reference panel of large families, taking blood samples from each of their members to build up a cell bank for genetic typing.

The researchers identified the LSC17 score by sampling the leukemia stem cell properties of blood or bone marrow samples from 78 AML patients from the cancer centre combined with molecular profiling technology that measures gene expression.

Palsson and his team were interested in red blood cells because they are the simplest human cells and are readily available from blood samples.

Grainger's team sampled serum (blood with the clotting cells removed) from 36 people with coronary disease diagnosed by angiography and 30 healthy people.

Collaborating with Ian Paul, a pediatrician at the Penn State Milton S. Hershey Medical Center, they took samples of blood and of cells inside the cheek from 39 healthy mother - child pairs.

Labs can test their proficiency at carrying out the polymerase chain reaction (PCR), a technique that generates usable quantities of DNA from cells in a tiny sample of blood or semen.

In the field, the researchers often had to use their vehicle batteries to power the centrifuges used to separate out white blood cells from their samples, and then add buffering chemicals to stabilise the DNA so it would not degrade under the African sun.

To treat hereditary blood diseases, doctors could take a sample of bone marrow cells from a patient, correct the faulty gene, and then grow healthy cells in the bioreactor and transplant them back into the patient.

To confirm that the missing mutations were important for generating an immune response, the researchers cultured a subset of the neoantigen protein fragments containing the tumor mutations with immune cells taken from three patients» blood samples.

Because CD4 + (helper) T cell responses have been shown to be sufficient for protection from WNV challenge (independent of B cells and CD8 + T cells) and crucial for viral clearance from the CNS, the researchers focused on the WNV - specific CD4 + T cell repertoires present in the blood samples.

In each blood sample, the researchers separated the plasma, the liquid part of the blood, from the blood cells.

The skin assay has been developed using cells isolated from blood samples from a range of healthy volunteers.

They found that there was no measurable difference between the concentrations of stem cells in the various samples, despite the fact that the in vivo sample was part of a dynamic environment — which included enzymes and blood flow — making it easier for the stem cells to migrate away from the target site.

Overall, including all genomic variations present in most if not all tumor cells (clonal) as well as those present only in subsets of the cancer cells (subclonal) from tumor tissue, the researchers detected a total of 864 genetic changes in tissue samples across the three tumor types, and 627 (73 %) of those were also found in the blood.

For the study, conducted as part of the doctoral thesis of Mahesh Raundhal, a graduate student in the laboratory of Prabir Ray, Ph.D., Pitt professor of medicine and co-senior author, the research team examined lung cell samples obtained from patients also participating in the Severe Asthma Research Program (SARP), a National Heart, Lung, and Blood Institute of the National Institutes of Health - sponsored program to improve the understanding of severe asthma.

In the early 1990s, Carol Jenkins of the Papua New Guinea Institute of Medical Research developed the cell line from blood samples drawn from a member of the Hagahai tribe.

The protocol can be used to measure adaptive responses following the stimulation of whole blood samples or purified peripheral blood mononuclear cells (PBMCs) and includes a freezing step that allows the stimulated samples to be shipped from the collection site to the analysis facility.

Critical issues for this goal are the number of fetal cells which can be recovered from a blood sample, the purity of cell recovery, the quality of the recovered fetal cells DNA and the assay workflow allowing to develop a high - throughput analysis generating reliable results at a very affordable price.

To make the iPSCs, Cedars - Sinai investigators first took small samples of blood and skin cells from an adult.

Tissues being sampled include biopsy material from target organs, peripheral blood cells and serum / plasma, germline DNA, and stool for microbiota analysis.

The researchers conducted their study by using a highly sensitive probe to scrutinize minute numbers of leukemia cells in blood samples previously collected from newborns who during childhood were diagnosed with leukemia.

In close collaboration with oncologists at the Olivia Newton John Cancer Research Institute (ONJCRI), the technology was tested on blood samples from melanoma patients and was able to track critical changes in spreading tumor cells before, during and after treatment.

DNA samples were isolated from blood cells, amplified by PCR and digested with Tru1l.

• Detect Zika virus in blood and urine samples within hours and distinguish between its African and American strains • Distinguish between Zika and dengue • Discriminate different types of bacteria, like E. coli • Detect cancer cell mutations • Detect antibiotic resistance genes • Read human genetic information from saliva sample

a Cellular composition analysis for 18 cell types shows an increase in NK - cells - resting and T - cells - CD8 and decrease in Neutrophils composition from pre - to post-mortem blood samples.