Sentences with phrase «cells from younger donors»

The researchers also found similar associations with red blood cells from younger donors.

He did, however, publish a paper last year documenting a study in which he infused three cancer patients with white blood cells from young donors who had been injected with G - CSF.

Not exact matches

They want to explore whether mitochondria from younger donors» cells may stimulate the older eggs» ability to be fertilized and develop normally.

Increasing the expression of one of the proteins, SIX3, in the insulin - producing cells isolated from younger donors enhanced their ability to respond efficiently to rising glucose levels.

But brain cells that had been created using the direct conversion technique had different patterns of gene expression depending on whether they were created from young donors or older adults.

Prins took human prostate stem cells from deceased young adult male organ donors and implanted the cells into mice, where they formed human prostate tissue.

This is the first study to suggest that red blood cell transfusions from young donors and from female donors may be associated with poorer survival in recipients.

«Our new approach takes young and aggressive macrophages from the bone marrow of a human donor and removes a key safeguard that cancer cells have co-opted to prevent them from being engulfed,» Alvey said.

Proliferative response of corneal endothelial cells from young and older donors.

Allogeneic cell transplantation enables the use of «younger» cells, from fetal origins (e.g., umbilical cord blood, placenta) or healthy donors, which are considered to be effective due to higher regenerative potential and plasticity.

The present study employed Ighb scid mice reconstituted with normal lymphocytes from young (2 -3-mo-old) and aged (20 -25-mo-old) donors and immunized with a protein conjugate of the hapten (4 - hydroxy -3-nitrophenyl) acetyl (NP) to determine whether the molecular changes in antibody repertoire reflect senescence in the B cells or whether they are mediated by the aging helper T lymphocytes.

When T cells were donated by young mice, the anti-NP response in GC was dominated by the canonical V186.2 gene, even if the responder B cells came from aged donors.

To examine the effect of age on the cognate function of CD4 T cells, we have used a novel adoptive transfer model that allows us to compare identical numbers of antigen - specific naive T cells from young and aged TCR transgenic (Tg) donors.

However, when the mice were reconstituted with T cells from aged donors, the expression of the V186.2 gene by young B cells was diminished and the response was dominated by the C1H4 gene, another member of the V186.2 / V3 family.