Sentences with phrase «cells function normally»

Vitamin C plays a vital role by supporting immune function, helping white blood cells function normally, and it also promotes cartilage growth and tissue repair.

To ensure that cells function normally, tens of thousands of genes must be turned on or off together.

Normally, MIR506 plays an important role in regulating cell behavior; adequate levels help the cells function normally, while decreased levels trigger cell growth and expansion occurring in tumors.

In previous testing of the woman's blood, her immune cells functioned normally.

Not exact matches

G6PD deficiency is an inherited condition in which the body doesn't have enough of the enzyme glucose -6-phosphate dehydrogenase, or G6PD, which helps red blood cells (RBCs) function normally.

Knowing TH17 cells need to function in a variety of tissue environments throughout the body, Sundrud's team wondered if and how these cells might use different tools to behave normally in one environment — or tissue — than they'd use in another.

Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.

It has been particularly difficult to measure changes in electrical functions of cells grown within Organ Chips that are normally electrically active, such as neuronal cells in the brain or beating heart cells, both during their differentiation and in response to drugs.

Indeed, after Siddle added a squirt of interferon - gamma — a chemical messenger that activates numerous genes involved in producing MHC antigens — to cells cultured from devil tumors, the MHC genes functioned normally again, and the tumor cells» identity cards showed up, plain as day.

The two genes implicated — GNAQ and GNA11 — code for proteins (known as G proteins) that normally function as molecular on - off switches, regulating the passage of information from the outside to the inside of a cell.

First author Kim Martinod, a graduate student in the Immunology Graduate Program at the Harvard University Medical School, found that, in response to vein constriction, these «rescued» mice now could function normally, forming clots as efficiently as mice with a functioning Pad4 gene, demonstrating that the Pad4 gene did produce a functioning PAD4 enzyme in these white blood cells to regulate blood clotting.

There, they began to specialize, creating all of the secondary or «daughter» cells that such stem cells normally produce — including healthy T cells with functioning ADA genes.

The study published in Cell Metabolism reports a mechanism by which two types of brain cells, neurons and glia, normally support each other's functions.

This endosomal pathway normally breaks things down to absorb and recycle their components, but Ebola virus hijacks the pathway's functions to infiltrate cells.

But in malignant cancer, normally healthy cell functions often lunge into destructive overdrive.

Thus, cells appear to require a double dose of PAR - gene proteins to function normally.

«AMPK normally helps to turn on nNOS function in muscle cells, for instance when we exercise, and when dystrophin is lost, AMPK does not turn on appropriately.»

However, it's heartening to think that this is not an insurmountable obstacle; a short period of recovery sleep before transplant can restore the donor's cells» ability to function normally.»

Even just two hours of recovery sleep restored the ability of the animals» stem cells to function normally in the transplantation tests.

Normally, they open and close very quickly and in sync with other cell functions to make the heart work.

Patients with Parkinson's disease, cardiovascular disease, and cystic fibrosis may have something in common: cells in their disease - affected tissues may produce misfolded proteins that are incapable of functioning normally.

The disabled gene codes for the protein PD - 1, which normally puts the brakes on a cell's immune response: cancers take advantage of that function to proliferate.

«Our study sheds new light on how genes normally function in sperm stem cells,» says Cairns.

Scientists typically don't classify viruses as living organisms, but giant viruses like these, with their own protein - making machinery and other functions normally carried out in living cells, blur the lines between what's alive and what isn't.

A-T is caused by lost function in a gene, ATM, which normally repairs damaged DNA in the cells and preserves normal function.

The OHSU team discovered a way to use small molecules that enter cells, fix the misfolded proteins and allow the proteins to move to the correct place and function normally again.

The latest findings from Sullivan's lab, published in the June 5 issue of Journal of Cell Biology, reveal new aspects of a remarkable mechanism that carries broken chromosomes through the process of cell division so that they can be repaired and function normally in the daughter ceCell Biology, reveal new aspects of a remarkable mechanism that carries broken chromosomes through the process of cell division so that they can be repaired and function normally in the daughter cecell division so that they can be repaired and function normally in the daughter cells.

A normally functioning adult human brain has the ability to partially replenish or repair itself through neurogenesis, the proliferation and development of adult neural progenitor / stem cells (aNPCs) into new nerve cells.

«If our predictions hold true, tumor cells with intact p53 may show the best response to therapy targeting the IGF - 1R signal; however, when p53 is not functioning normally, response to this therapy may not be as expected,» said Greenberg, the study's corresponding author.

In the study, vitamin B - 6 also was used to treat the damaged RPE cells producing healthy cells that functioned normally.

Because most immune cells typically can't get into the brain, microglia are adapted to perform multiple functions that are normally handled by several different types of immune cells.

p53 is therefore well - studied as an oncogene, or a gene that when not functioning normally can contribute to a normal cell becoming cancerous.

The drug increases production of fetal hemoglobin, which functions normally in individuals with sickle cell anemia.

However, these tissues can continue to look and function normally despite accumulating a large proportion of cells that are carrying mutations that promote cancer formation.

There is brain - derived neurotrophic factor (BDNF): Some researchers suspect a variant BDNF gene might prevent hippocampal cells in the brain from functioning normally and possibly increase the risk of depression.

Tau protein normally helps brain cells function, but in Alzheimer's disease, tau clumps up in «tangles» inside the cells.

In the blood, too much cholesterol can be bad, but appropriate levels of cholesterol are critical for cells to function normally.

In all living organisms, the cell cycle must be tightly regulated to ensure that new cells are created only when necessary and have an accurate copy of DNA to function normally.

As more cancer cells are produced, they stop the healthy white blood cells from growing and functioning normally, by crowding out space in the blood.

Some of this programming watches out for conditions emerging within the cell that could put the rest of the body at risk; similar systems exist because the body no longer has need for the function that the cell normally fulfils.

Among many other important biological and immunological functions, Growth Factors cause the growth of new blood vessels, connective and nerve tissues by the activation of Stem Cells that are normally found in all parts of the human body.

This program has provided the first comprehensive picture of how a gene normally associated with cancer can influence development, survival and normal function of brain cells central to age - associated neurodegenerative disorders such as Parkinson's disease.

Dehydrated skin disrupts normal skin function, resulting in skin cells that do not shed normally and build up at the surface, appearing rough and dull.

Every cell in your body needs B12 to function normally, but the body is unable to produce it.

Without these fats, cells fail to grow and function normally, increasing the chance of cell abnormalities and degenerative disease.

The function of the tiny «energy engines» — mitochondria — inside every cell is improved, whether joint cartilage cells or retinal cells, so the cells which depend on those mitochondria for energy can function more normally again.

Blood delivers oxygen to cells in the body and brain so they can function normally.

The scientists came to the conclusion that the sulforaphane was improving the function of the patients» brain cells, some of the ones which are normally malfunctioning in autism patients.

The symptoms that you normally associate with aging (decreased mobility, decreased mental function, aches & pains, wrinkles, etc.) are also the result of accumulated damage from free radicals to your cells.

These function outside a cell, and are normally associated with the break down of food into the usable, basic elements like Amino Acids, Essential Fatty Acids, Vitamins, Minerals etc... Most digestive enzyme supplements are focused on the breakdown of macro nutrients: Carbohydrates, Fats, and Protein.