«Capsaicin inhibits the growth of human prostate cancer
cells in petri dishes and mice,» said lead researcher Dr. H. Phillip Koeffler, director of hematology and oncology at Cedars - Sinai Medical Center and a professor of medicine at the University of California, Los Angeles.
In 1997, molecular biologist Chi Dang of Johns Hopkins Medical School in Baltimore, Maryland, found that blocking one enzyme involved in glycolysis, lactate dehydrogenase A (LDH - A), could slow the growth of cancer
cells in petri dishes.
He has also shown that the technique stirs changes in mouse
cells in petri dishes.
Growing
cells in Petri dishes sounds like the stuff of science fiction, but the basic elements of the science are actually decades old.
The scientists grew
these cells in a petri dish and implanted them in mice engineered to be infertile.
But there are many hurdles: Among them, growing enough of
the cells in a petri dish and ensuring that they connect to «the existing machinery» in the eye, says Hendrik Scholl, who co-directs the Center for Stem Cells and Ophthalmic Regenerative Medicine at Johns Hopkins University in Baltimore, Maryland.
For his prototype he is growing mouse muscle from stem
cells in a petri dish.
Developing safe and effective therapies for conditions such as peripheral nerve disorders requires the ability to take investigations from
cells in a petri dish to patients in a clinic.
For example, researchers could use the sound waves to measure elastic properties of
cells in a petri dish, seeing how they respond to forces.
The technique's success in the body of an animal (rather than just
cells in a petri dish) has Dzau hopeful that he can adapt it to treat humans within a decade.
He would place
these cells in a petri dish, feed them and wait for them to grow.
Two men with prostate cancer,
cells in a petri dish, a loss of function that may or may not translate into pathogenicity: This does not merit my mental energy.
While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human
cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.
After treating the IPS
cells in a petri dish to set them on a path to mature into dopaminergic neurons, the cells were grafted into the dopamine - deficient hemispheres of the parkinsonian rats» brains.
Yet in 2006, Shinya Yamanaka at Kyoto University in Japan reported a «crazy» experiment (Hochedlinger's word) to show that mouse skin
cells in a petri dish, aided by four genes and viruses that inserted the genes into the cells» DNA, could achieve something like the newt's developmental reversal, becoming just about any cell in the mouse's body.
In the second study, a team led by Shahin Rafii at Weill Cornell Medicine in New York City used adult mouse cells as their starting material, and then guided them through several steps — including exposure to some of the same gene - activating proteins — to create mature blood stem
cells in a petri dish.
In order for the revival of the Heath Hen to be possible, engineered
cells in a petri dish must develop into live chicks.
But editing the DNA of
cells in a petri dish — or even curing a mouse of a disease — is one thing; making the hot new technology work in humans is a whole other challenge.
Massachusetts Institute of Technology (MIT) researchers have discovered a new way to model malaria using stem
cells in a petri dish, which will allow them to test potential antimalarial drugs and vaccines.
The specific drugs designed by WAVE have been tested in
cells in a petri dish, where they successfully lowered the mutant protein whilst leaving the normal version relatively untouched.
Stanford scientists grew brain
cells in a petri dish to show the 3D cluster formation in early forebrain development.
And in the latest issue of Stem Cell Reports, researchers in the laboratory of Gladstone Cardiovascular and Stem Cell Research Director Deepak Srivastava, MD, reveal that they have done the same to human
cells in a petri dish.
It is now almost routine to grow skin cells from a patient with, say, a neurological disease; turn them into pluripotent
cells in a Petri dish; convert the cells into nerve cells to study the disease process; and contemplate using the cells to repair the same patient's damaged brain.
And then dripped their blood on human breast cancer
cells in a petri dish over the next six hours.
Within hours the blood of those fed walnuts is able to suppress the growth of breast cancer
cells in a petri dish.
This makes sense, given new research showing, for example, that apple peels have potent antioxidant and antiproliferative effects on human cancer
cells in a Petri dish.
Scientists at South Dakota State University tested the effects of this substance, known as PEITC, on human cancer stem
cells in a Petri dish.
There are a number of specific compounds in plant foods that look promising, but that's based on in vitro studies like this, where they basically just drip some plant compound on bone
cells in a petri dish and see a boost in bone builder cells, or a drop in bone eater cells.
However, research in actual cats — not cat
cells in a petri dish — has failed to show consistent success with the treatment.
Also in Encounters, Korean artist Yeesookyung's ceramic shards rejoined with golden epoxy were gathered together in Thousand (2014), appearing like mutating
cells in a petri dish.
Her lab even turned those stem cells into nerve cells and beating heart
cells in a petri dish, she says.
Not exact matches
Applied to
cell cultures
in a
petri dish, it works.
In the meantime, researchers could use the cells to study neurological and psychiatric disorders in Petri dishe
In the meantime, researchers could use the
cells to study neurological and psychiatric disorders
in Petri dishe
in Petri dishes.
Chrousos's group looked for CRH
in human trophoblast
cells, special
cells that help form the placenta,
in petri dishes.
In addition to helping understand disease by providing more powerful study models, «what this technology would allow you to do is reprogram a skin cell, for example, from a Parkinson's patient... into a pluripotent cell and then in a petri dish redirect that cell into... a neuron» to treat that patien
In addition to helping understand disease by providing more powerful study models, «what this technology would allow you to do is reprogram a skin
cell, for example, from a Parkinson's patient... into a pluripotent
cell and then
in a petri dish redirect that cell into... a neuron» to treat that patien
in a
petri dish redirect that
cell into... a neuron» to treat that patient.
We've also found that
in a
petri dish, the anti-quorum-sensing molecule prevents Pseudomonas from killing human lung
cells and from making a biofilm that would enable it to mount an attack.
«We know that if you take these tumor
cells out of a patient and put them
in a
petri dish, they can be killed by chemotherapy,» Beatty said.
Scientists have previously shown that isolated germline stem
cells from mice can turn into eggs
in a
petri dish.
To find out, they put droplets of culture medium that cancer
cells had grown
in on one side of
petri dishes.
Because the sperm
cells used
in IVF often need all the help they can get, switching to the diamond
petri dishes could give them just the boost they need to fulfill their destiny — thus potentially ramping up the notoriously low success rate of IVF.
«To date, there has been no systematic means of assessing the fidelity of cellular engineering — to determine how closely
cells made
in a
petri dish approximate natural tissues
in the body,» says George Q. Daley, MD, PhD, Director of the Stem
Cell Transplantation Program at Boston Children's and senior investigator on both studies.
A technician
in a Kyoto University lab uses an electronic pipette to transfer
cells into
petri dishes before they are placed into an incubator.
These immortal precursor
cells could then be «grown up»
in petri dishes and differentiated into normal fat
cells.
These artificial environments produce
cells and tissues that resemble the real thing more closely than those grown lying flat
in a
petri dish.
Compounds from grapes may kill colon cancer stem
cells both
in a
petri dish and
in mice, according to a team of researchers.
By performing experiments
in petri dishes and with mice, they found that panobinostat, a drug designed to change the way
cells regulate genes, may be effective at inhibiting DIPG growth and extending survival rates.
The team first used the tried - and - true method of growing yeast
in Petri dishes and painstakingly counting how many times an individual yeast
cell produced a daughter
cell.
The new method has numerous advantages: researchers can sample individual
cells of a tissue culture directly
in the
petri dish.
In a paper published Sept. 21 in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shap
In a paper published Sept. 21
in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shap
in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse
cells to reconstitute a stable version of this clockwork for the first time
in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shap
in a
petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shape.
One innovation that Post hadn't described earlier is a circular structure
in the middle of the
petri dish around which the
cells grow.