Sentences with phrase «cells in a single experiment»

In this presentation, we will discuss how the Illumina Bio-Rad Single - Cell Sequencing Solution combined with the Bio-Rad S3e Cell Sorter enhances single - cell studies and provides researchers with a robust, scalable, and user - friendly workflow that enables transcriptome profiling of hundreds to tens of thousands of single cells in a single experiment.

Not exact matches

In an experiment they conducted largely for fun, Weibel, George Whitesides of Harvard University and their colleagues yoked nanosize polystyrene beads to a single - cell green alga called Chlamydomonas reinhardtii.

In a recent proof - of - concept experiment, Abate and his colleagues performed single - cell genomic sequencing on a sample of seawater.

In 2009, from experiments at the RIKEN Center for Developmental Biology in Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGCIn 2009, from experiments at the RIKEN Center for Developmental Biology in Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGCin Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGCs.

This image depicts a single cell experiment in which a human neutrophil was picked up by a micropipette (top panel) and brought into close contact with S. Typhimurium cells immobilized by optical tweezers.

By now, European astronauts had hoped to be established in their space laboratory called Columbus, where they would be melting and solidifying conductive metals, studying microgravity effects on single - celled organisms, investigating human balance disorders, and carrying out dozens of other experiments.

In an experiment that earned him a Nobel Prize, he found that a single - celled creature named Tetrahymena possessed some RNA molecules that could act like simple enzymes.

Their series of experiments showed that a single application of concentrated, mature B cells accelerated wound healing and improved the quality of tissue repair in both animal models.

In a famous set of experiments in human subjects in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain cell in the hippocampus region — the so - called Jennifer Aniston neuroIn a famous set of experiments in human subjects in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain cell in the hippocampus region — the so - called Jennifer Aniston neuroin human subjects in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain cell in the hippocampus region — the so - called Jennifer Aniston neuroin 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain cell in the hippocampus region — the so - called Jennifer Aniston neuroin the hippocampus region — the so - called Jennifer Aniston neuron.

The assay can measure the lag times and growth rates of as many as 80,000 individual microcolonies in a single 24 - hour experiment, opening up a powerful new high - throughput tool to study the complex interplay between cell growth, division and metabolism under environmental conditions that are likely to be ecologically relevant but had previously been difficult to study in the laboratory.

Not only does this let them build up complex tissue components like the mammary gland, but also to experiment with specifically adding in a single cell with a known cancer mutation to different parts of the organoid to observe its effects.

Another important advance, says Pralle, is that whole networks of cells were activated for the first time, compared with single or small groups of neurons stimulated in previous monkey and rodent experiments.

In an unprecedented evolutionary experiment, scientists from GEOMAR Helmholtz Centre for Ocean Research Kiel and the Thünen Institute of Fisheries Ecology demonstrated that the most important single - celled calcifying alga of world's oceans, Emiliania huxleyi, is only able to adapt to ocean acidification to a certain extent.

The university recently received international attention after a group of 16 scientists based at the Key Laboratory of Gene Engineering published the results of a controversial experiment in which they genetically modified single - cell human embryos to repair the human β - globin (HBB) gene in a procedure aimed at preventing a serious blood disorder (www.sciencemag.org/content/348/6234/486.full).

In their initial experiments, Hwang and his colleagues used cells from a single donor to try to create embryonic clones; they transferred nuclei from ovarian cells back into the donors» own oocytes.

Experiments on cells from frogs have shown that sensitive light - detecting cells in vertebrate eyes, called rod cells, do fire in response to single photons.

We showed previously that myostatin circulates in the blood and that systemic effects can be achieved by implanting myostatin - expressing cells into a single site in the lower limb [21]; however, there have been no experiments that have demonstrated conclusively that myostatin normally acts systemically.

This technique, which scientists are rapidly automating, may eventually displace crystallography as the tool of choice in many cell biology studies because it does not require the subject to crystallize and sometimes can even reveal multiple conformational states in a single experiment.

The Scientist spoke with the developers of four recent applications of single - cell lineage tracing experiments — examples that reflect the power biologists have in 2016 to answer fundamental questions about how tissues and organs form.

Each spot is a unique experiment that edits or silences a single gene in cells growing above the RNA spot.

It is now feasible for researchers to characterize thousands of single cells in one experiment.

Thus, in a single experiment, the authors demonstrated that (1) CD4 + and CD8 + T - cells were the mediators of immune system rejection of transplanted tumor cells, and (2) d42m1 escape tumors develop from T - cell - dependent selection favoring cells without the spectrin - B2 antigen.

The last few years have seen the scale of single - cell RNA - seq (scRNA - seq) experiments increase exponentially, greatly enhancing our understanding of cell biology in development and disease.

These methods integrate single - cell experiments and discrete stochastic analysis to predict complex gene expression and signaling behaviors in Saccharomyces cerevisiae — or yeast, a scientific - lab standard since yeast and human cells share many genes.

(B) Shown is a representative plot of viability eFluor780 stained samples (left) and the percentage of live cells (mean ± SD, right) of a single representative experiment, shown in Fig 1D of 3 independent experiments.

As the team demonstrated in their January paper, scientists can use the technology to see huge amounts of data from a single cell and large - scale data patterns across cells, all in a single experiment.

For example, in single cell experiments, it gives the user the broadest range of force control available.

In our lab we use a combination of quantitative single cell experiments and computer / in silico models to better understand miRNA regulatioIn our lab we use a combination of quantitative single cell experiments and computer / in silico models to better understand miRNA regulatioin silico models to better understand miRNA regulation.