Sentences with phrase «cells in another test tube»

Significantly, disabling both anti-apoptotic proteins, Bcl - 2 and Bcl - xL, in conjunction with Mcl - 1, caused profound cell death of leukemia cells in the test tube as well as in animal models of AML.
Now researchers have found a way to kill tumor cells in test tubes without inflicting any collateral damage on healthy cells.
In 2010, Gordon's team demonstrated they could reverse an asthmatic response in human cells in a test tube.
Numerous small studies show a reduction in depression and fatigue in cancer patients who received Reiki, and a rigorously controlled study in the Journal of Orthopaedic Research showed that cells in test tubes treated by Reiki practitioners grew better than those in an untreated control group.
And in a recent University of Michigan study, a red wine compound helped kill ovarian cancer cells in a test tube.
Since these experiments were only performed on cancer cells in test tubes, the researchers took the next step and ran tests on breast cancer tumors in live mice.

Not exact matches

Researchers at Tufts Medical School noticed that cancer cells being grown in the lab multiplied more quickly in polyester test tubes than in glass.
The audience roars with laughter as Polish tells how he initiated select new members into the cell biology lab he worked in after college with strategically placed miniature dry - ice bombs fabricated from plastic Eppendorf test tubes.
Further experiments in test tubes showed which portion of the sugar molecule the liver cells were noticing.
Stahelin and co-investigator Smita Soni, a postdoctoral researcher at the Indiana University School of Medicine, found that VP40 is able to assemble in vitro (i.e., in a test tube), without any human cells present and mediate formation of virus - like particles when the human lipid phosphatidylserine is found in solution with VP40, but not other control lipids.
To start, she used a cotton swab to get a sample of cells from her cheek, boiled them in a test tube in her kitchen to free the DNA, then added primers, nucleic acids that mark the part of the sequence.
Smider and colleagues took serum — blood with the cells removed, leaving antibodies behind — from four immunized cows and tested it against different types of HIV virus in a test tube.
Test - tube experiments showed that BMAA can kill motor nerve cells in the spinal cord, the very ones destroyed by ALS.
In further test tube experiments, the researchers treated the immortalized white blood cells with both chemical and genetic blockers, called small interfering RNA (siRNA), designed to render either p70S6K or GRB10 nonfunctional.
Living cells have been doing this for billions of years, and researchers have done it in test tubes for decades.
In test tubes, this gene caused the cells to produce extra amounts of a chaperone molecule that ordinarily helps a cell recognize misfolded proteins.
To determine if Sup35 could change shape on its own or if it needed help from other molecules in the cell, the team studied the purified protein in the test tube.
De Lange cautions that they still need to demonstrate that what they see in their test tube studies occurs in living cells.
To see if the same chain of events happens in rheumatoid arthritis, Smith's team tested whether various kinds of fibroblasts would spur T cell migration in test tubes.
While most research studies begin in test tubes, cells grown in the laboratory and animal models before moving to humans, the opposite is true here.
«The chemistry of cells, unlike more traditional chemistry in test tubes, is highly dependent on where a chemical reaction is occurring,» said Christine Payne, an associate professor in the Georgia Tech School of Chemistry and Biochemistry and one of the paper's senior authors.
The placebo - controlled trial in nearly 9500 women tested a gel called PRO 2000, a so - called polyanion that prevented the AIDS virus from entering human cells in test - tube and monkey studies.
Using in vitro, or test tube, experiments, the researchers applied these chemicals to human cancer cells to measure changes of estrogen receptor - and androgen receptor - target genes and transcriptional activity.
But fetal tissue is scarce, and research in the past several years suggests that stem cells, which can be mass produced in a test tube, can also replace damaged brain tissue.
In test - tube experiments with hamster cells, the DNA vaccine created mRNA that both copied itself like it would in the alphavirus and produced antigeIn test - tube experiments with hamster cells, the DNA vaccine created mRNA that both copied itself like it would in the alphavirus and produced antigein the alphavirus and produced antigen.
The researchers note that this study of digestion in the test tube is limited by not including the roles of gut cells, which absorb and secrete metabolites as well.
By combining different fractions in a trial - and - error fashion with the known NER proteins, Wood's team eventually identified the simplest mixture that would repair DNA in the test tube (Cell, vol 80, p 859).
Other than in previous publications, optical rogue waves in this system are clearly ruled by atmospheric turbulence in a gas cell, effectively enabling the observation of a storm in a test tube.
According to McCague, «the rarity of human prostate cancer cell cultures makes studying tamandron's potential difficult in the test tube
Applying a new method that is used mainly in stem - cell research and regenerative medicine, researchers from the Technical University of Munich have now devised a robust intestinal model for molecular research into incretin release in a test tube (in vitro).
Researchers at the Cells - in - Motion Cluster of Excellence at the University of Münster (Germany) have now developed a method enabling them to better evaluate and study the activity of inflammatory cells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organCells - in - Motion Cluster of Excellence at the University of Münster (Germany) have now developed a method enabling them to better evaluate and study the activity of inflammatory cells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organcells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organcells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organisms.
«A change that makes a slightly less effective protein in the test tube can turn into a completely fatal mutation in the cell.
They used immortalized myeloid precursor cells — so - called ERHoxb8 cells — which multiply almost endlessly in a test tube and, under certain conditions, can develop into immune cells.
Their idea emerged from test - tube experiments that Munn did years ago, when he showed that some macrophages could stop T cells in their tracks by starving them of a building block called tryptophan.
A series of experiments showed that SW033291 could inactivate 15 - PGDH in a test tube and inside a cell, and, most importantly, when injected into animal models.
In test - tube experiments, WS cells are much more susceptible than normal to harm from a compound that is toxic to DNA.
But that was achieved in test tubes, not inside living cells.
For one, Brca1 might behave differently when floating free in a test tube than in the cell, where it's only been observed bound to other proteins.
Scientists will have to wait a while to find out whether cells that live longer in a test tube will translate into longer lived animals: Cows can live about 20 years.
The researchers have demonstrated that in test tubes a particular chemical, called CAI - 1, can induce deadly cholera cells to turn off their virulence genes.
In test tube experiments, they linked virus fragments to human cell proteins; adding this complex to the T cells provoked them to fight the virus.
Using genetic techniques, the Imperial team knocked out the Hhat function in pancreatic cancer cells and, as they hoped, the cancer cells showed substantially reduced growth and ability to spread in a test - tube assay.
The test tube finding, reported in the current Cell, could help explain the formation of prions — the tangled proteins that are implicated in mad cow disease and several human brain disorders — and eventually may lead to a way to smooth out these rogue proteins.
«One of the unique features of µSCALE is that it allows researchers to rapidly isolate a single desired cell from hundreds of thousands of other cells,» said Bob Chen, a doctoral student in Cochran's lab who wrote the software to examine and detect signs of interesting protein activity within the test tubes.
Next, in a laboratory test - tube experiment they found that mixing serum from women with classic or atypical HELLP together with a monoclonal antibody the blocks complement, resulted in a significant decrease in the killing of cells in the modified Ham test — from about a 34 % kill rate down to a 5 % kill rate, the amount seen in healthy individuals.
In test tube studies and experiments with cells, the researchers found that the TIA1 mutation causes the protein to become more «sticky,» delaying the normal disassembly of stress granules, trapping TDP - 43.
It can be made in a biodegradable ink form, enabling the researchers to 3D print it into structures that encourage cartilage cells in the knee to form and grow — a process that they have demonstrated in test tubes.
In the test tube, the nanogenerators killed leukaemia, lymphoma, breast, ovarian, neuroblastoma, and prostate human cancer cells.
In their study Loeken and her group, including Yichao Wu, Marta Viana, and Shoba Thirumangalathu, used mice and cell lines to test their hypothesis that AMPK might be stimulated in the embryo and that stimulation of AMPK was responsible for blocking Pax3 expression and causing neural tube defects in response to high glucosIn their study Loeken and her group, including Yichao Wu, Marta Viana, and Shoba Thirumangalathu, used mice and cell lines to test their hypothesis that AMPK might be stimulated in the embryo and that stimulation of AMPK was responsible for blocking Pax3 expression and causing neural tube defects in response to high glucosin the embryo and that stimulation of AMPK was responsible for blocking Pax3 expression and causing neural tube defects in response to high glucosin response to high glucose.
Because scientists could use the new stem cells to make any tissue in a test tube, they might have an easier time studying certain diseases and treatments.
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