Sentences with phrase «cells in brain tissue»

Microinjection of membrane - impermeable molecules into single neural stem cells in brain tissue.

After introducing stem cells in brain tissue in the laboratory and seeing promising results, Prof. Offen leveraged the study to mice with Alzheimer's disease - like symptoms.

Doing this type of study on cells in brain tissue has been challenging because the cells are densely packed and intimately intertwined.

Grima also observed this same clumping of Huntingtin protein with RanGAP1 and nuclear pore proteins to the wrong place in the cell in brain tissue and cultured brain cells derived from deceased patients with Huntington's disease.

Not exact matches

The brain tissue develops in three dimensions, allowing for the cells to connect more like those in natural...

The building block electronic and protonic actual occasions are, in the case of human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with cells, others which answer to Aristotle's levels of tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.

If we could but restore or bring about the normal functioning of brain cells and nerve tissues, as well as their own subsidiary chemical activity in such cases, then mental life would come flooding back in fullness and richness.

Include protein - rich food in your diet — this means more of fish and lean meats because your body needs amino acids to build new cells and develop feat brain, heart, muscle and tissue.

Scientists have long speculated that astrocytes, the cell type that controls many neuronal functions, give rise to neural stem cells in damaged brain tissue.

She demonstrated that early experience leads to lasting changes in the molecular structure of the brain and discovered a gene involved in the spread of brain cancer cells into healthy brain tissue.

Balls of brain tissue generated from stem cells are enabling us to understand the underlying differences between people who struggle to be sociable and those who have difficulty reining themselves in.

Alfano states «Resonant Raman using the laser pointer 532 nm has become an e?cient tool for investigating molecular components in tissues and cells, providing more detailed information and a way to detect diseases like skin cancer, brain cancer, or atherosclerosis — in mere seconds.»

Hemoglobin is the main constituent of red blood cells and allows the cells to pick up oxygen from the lungs and drop it off in tissues throughout the body, from the brain to the muscles.

The increased alpha wave activity was greatest in brain tissue directly beneath to the cell phone, strengthening the case that the phone was responsible for the observed effect.

The researchers tinkered with the voltage in cell membranes of developing African clawed frogs (Xenopus laevis) and found that electric charge plays a role in how big the brain grows and what kind of tissue developing cells grow into.

Recent studies suggest that the total loss in brain volume due to atrophy — a wasting away of tissue caused by cell degeneration — between our teen years and old age is 15 percent or more, which means that by the time we're in our seventies, our brains have shrunk to the size they were when we were between 2 and 3 years old.

Minuscule blobs of human brain tissue have come a long way in the four years since scientists in Vienna discovered how to create them from stem cells.

Four weeks after the team switched on the enzyme, they found that tissue had regenerated in several organs, new brain cells were developing and the mice were living longer.

They tested neural tissue from people who had died from Huntington's disease, a degenerative disorder of nerve cells in the base of the brain.

In one such approach, researchers surgically remove brain cells, use viruses to transfer genes to the cells, and then graft them back into the animal's brain tissue.

Researchers also studied the brain tissue of the infected mice under a microscope and found that the memory problems tracked with changes in nerve cells.

They also applied it to human brain tissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subTissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtypes.

The result in both cases is that they rub against and irritate the brain tissue, and the nerve cells around the electrodes die.

Saatchi, which is owned by France's Publicis Groupe, SA, chose LifeStraw over a field of competitors that included a reusable controller to improve the distribution of IV fluids, a collapsible wheel that can be folded down for easier storage when not in use on bicycles or wheelchairs, an energy - efficient laptop designed for children in developing countries, a 3 - D display that uses special optics and software to project a hologramlike image of patient anatomy for cancer treatment, an inkjet printing system for fabricating tissue scaffolds on which cells can be grown, a visual prosthesis for bypassing a diseased or damaged eye and sending signals directly to the brain, books with embedded sound tracks to help educate illiterate adults on health issues, a phone that provides telecommunications coverage to poor rural populations in developing countries, and a brain - computer interface designed to help paralyzed people communicate via neural signals.

To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS) imaging, and demonstrated its use in live cancer cells, tumor xenograft tissues, primary neurons and mouse brain tissues.

This technique is able to distinguish cancer cell lines with differing metabolic activities and reveals heterogeneous uptake patterns in neurons, mouse brain tissues and tumor tissues with clear cell - to - cell variations.

A team of multidisciplinary researchers with expertise spanning biotechnology, information technology, and medicine have used a combination of several «omics technologies to map proteins down to the single cell level, showing both proteins restricted to certain tissues — such as the brain, heart, or liver — and those present in all tissues.

Glioblastoma is the most lethal form of primary brain tumor and leads to death in patients by invading the brain tissue in a process that allows single cells to move through normal brain tissue, which makes complete surgical removal of the tumor impossible.

But fetal tissue is scarce, and research in the past several years suggests that stem cells, which can be mass produced in a test tube, can also replace damaged brain tissue.

On the other hand, the problem is, you know, with embryonic stem cells, they haven't been able to get stem cell lines from livestock animals that can proliferate in that way, without just sort of veering up in their own direction and turning into, instead of muscle, turning into brain tissue or bone tissue or something else.

Various reports in recent years have claimed that stem cells from one tissue — for example, blood — can mature into other tissues such as muscle or brain.

Two weeks post-infection, they saw that parasites appeared in the brain tissue adjacent to the endothelial cells.

During development, as an embryo forms differentiated tissues, liver cells, brain cells, muscle cells, the cells in those tissues begin to allow for the selective expression of genes contained in those same 3 billion nucleotides.

Using a powerful imaging technique that allowed the scientists to track the presence and movement of parasites in living tissues, the researchers found that Toxoplasma infects the brain's endothelial cells, which line blood vessels, reproduces inside of them, and then moves on to invade the central nervous system.

Split Pool Ligation - based Transcriptome sequencing (SPLiT - seq) is a scalable technique for characterizing RNA in individual cells that can be used to identify the various cell types found in the brain and other tissues.

Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow stem cells from mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same brew on human cells, the number altered was modest.

To search for such cells, the Mosers and their team delved into the medial entorhinal cortex (MEC), a slim arc of deep brain tissue where they had discovered the grid cells in 2005.

All formed the same types of stem cells, which give rise to «progenitor» cells that, in turn, divide into neurons and eventually organize themselves in six layers of brain tissue.

They zeroed in on three proteins found in the extracellular matrix that surrounds developing cells in fetal brain tissue.

They confirmed low levels of miR - 184 expression in human glioma tissue samples and cultured cell lines as well as an increase in the expression of SND1 compared to normal brain tissue.

«The most obvious function of glial cells has been related to their role in forming scar tissue to prevent the spread of injury and neuronal degeneration, but so much about their role in the brain is unknown.»

The thin walls of the microvessels mean that the oxygen levels in adjacent brain tissue are mirrored within the capillaries, which can signal to red blood cells to spring into action.

A September 2002 follow - up study found no evidence for widespread transdifferentiation of blood - forming stem cells in brain, liver, kidney, gut and other tissues.

Normally, adult stem cells can only morph into the type of tissue in which they reside, such as blood, brain or muscle.

In the brain tissue of Alzheimer's patients, the RNAs that encode synaptic proteins are degraded more rapidly than in healthy brain cells, the researchers founIn the brain tissue of Alzheimer's patients, the RNAs that encode synaptic proteins are degraded more rapidly than in healthy brain cells, the researchers founin healthy brain cells, the researchers found.

Importantly, individual classes of inhibitory neurons are quite sparse in the brain, so any unique features of those cells would likely have been lost in earlier studies that looked at the tissue as a whole.

«Our finding runs counter to the belief that increasing the reactivity of astrocytes and other glial cells in the brain helps maintain tissue integrity following TBI.

«By looking comprehensively at gene expression within cells, we can now spot numerous important differences in complex tissues like the brain that are invisible today,» said George Church, Ph.D., a Core Faculty member at the Wyss Institute and Professor of Genetics at Harvard Medical School.

These substances are both highly Poisonous to nerve cells, and so could cause the degeneration of brain tissue found in Alzheimer's patients.

The team found that people have large numbers of neural stem cells and progenitors early in life — an average of 1618 young neurons per square millimeter of brain tissue at birth.