Researchers have discovered a gene in zebrafish so powerful it can be used to redirect the fate of cells in the developing embryo to become beating heart cells, suggesting that a similar gene in humans could be used to generate heart
cells in culture for transplant in ailing people.
Not exact matches
Some reports, such as the Open Philanthropy Project's Animal Product Alternatives report and Van der Weele & Tramper (2014) suggest it is unlikely that
cultured meats will become cost - competitive with conventional meat.98, 99 One important contributing factor
in this conclusion, which is cited
in these reports, is the minimum costs of the growth medium necessary
for culturing the desired
cells.
In fact, these dead starter
culture cells and debris are an important food source
for subsequent generations of microbes, referred to as non-starter lactic acid bacteria (NSLAB).
He has more than fifteen years» experience
in the life science industry, including the product development, market development and commercialization of
cells, scaffolds,
cell reprogramming tools and
cell culture media
for regenerative medicine and bioprocessing applications.
In addition to managing the
cell bank, the facility makes
culture media and maintains a resale storeroom
for laboratory products.
Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs
for use
in experiments, helped clear HSV - 1 infection
in cultured human corneal
cells,
in donated human corneas, and
in the corneas of mice infected with HSV - 1.
For instance, to make a rod with collagen fibers aligned along its length (like a tendon) they
cultured chondrocyte
cells in a dog bone - shaped mold with loops on either end.
The team pumped around 50 million rat liver
cells into each of five bare scaffolds, then incubated the organs
in culture for two weeks.
The researchers — James Robl, a developmental biologist and his colleagues at the University of Massachusetts at Amherst, and Steve Stice at Advanced
Cell Technology
in Worcester, Massachusetts — inserted a marker gene fused with a gene
for resistance to the chemical neomycin into a
culture of connective tissue
cells called fibroblasts.
Now researchers at the University of Plymouth, working
in partnership with pharmaceutical company AstraZeneca, have
for the first time successfully
cultured and maintained
cells from the guts of rainbow trout, a recommended fish species
for toxicological studies.
New developments include reaction systems
for catalysis research, sampling from reactors, systems
for high - throughput applications
in synthesis, the handling of microorganisms or
cell -
culturing procedures, and more.
There will be several rounds of recruitment, and «specifically at this time, we are accepting applications
for both junior / senior postdoctoral researchers and recent graduates wishing to enroll
in our Ph.D. program as well as personnel with extensive expertise
in cell culture and one expert
in flow cytometry to fill
in the position of manager of the flow - cytometry platform.»
One of the 12 audience members was Ben Chao, a chemical engineer with a Ph.D. — not at all qualified to make a judgment on Scott's abilities
in the area of «Approaches to Developing Serum - Free Media Formulations
for Mammalian
Cells in Culture.»
For example,
cultured cells exhibit rhythmic oscillations
in gene expression where there is no input from the master clock.
Although the bulk of the commercial manufacturing uses
cultures of bacteria, such as Escherichia coli or Chinese hamster ovary
cells, a few biotech companies are trying to produce therapeutic proteins
in the milk of transgenic mammals (such as GTC Biotherapeutics, which is using goats; PPL Therapeutics, which is using sheep; and BioProtein Technologies, which is working with rabbits), transgenic chicken eggs (such as Avigenics or Vivalis), or even
in transgenic crops (such as ProdiGene or Meristem Therapeutics); but it is early days
for these «pharming» methods.
Oncologists William Hahn, Robert Weinberg, and colleagues at the Whitehead Institute
for Biomedical Research
in Cambridge, Massachusetts, mutated the gene
for one part of the enzyme and inserted it into
cultured human
cells from colon, ovary, and breast tumors.
Sicor,
for example, has recently acquired a plant
in Vilnius, Lithuania, and Genentech a
cell culture manufacturing facility
in Porriño, Spain.
Until recently, Ain was renowned
for a highly prized repository of 18 immortal cancer
cell lines, which he developed by harvesting tissue from his patients» tumors after removal, carefully
culturing them to everlasting life
in vials.
In addition, cell culture studies lasted two days in Gentzsch's study, whereas the clinical studies lasted for month
In addition,
cell culture studies lasted two days
in Gentzsch's study, whereas the clinical studies lasted for month
in Gentzsch's study, whereas the clinical studies lasted
for months.
Researchers have videotaped
cultures in which embryos develop but found no visual pattern that hints at which
cells are about to sprout, and staining
for certain patterns of gene expression has been inconclusive.
In 2009, from experiments at the RIKEN Center for Developmental Biology in Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGC
In 2009, from experiments at the RIKEN Center
for Developmental Biology
in Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGC
in Kobe, Japan, he found that when
culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic
cells to PGCs.
Using a labor - intensive
cell culturing technique
for hunting retroviruses that he had pioneered
in the 1970s, Ruscetti had transmitted the pathogen from patients» T -
cells to uninfected T -
cells in the laboratory.
In a previous related study published in the Journal of Materials Science: Materials in Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial cells to express 2.5 times more of a specific type of collagen responsible for blood vessel formation, as compared to endothelial cells cultured on bovine collage
In a previous related study published
in the Journal of Materials Science: Materials in Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial cells to express 2.5 times more of a specific type of collagen responsible for blood vessel formation, as compared to endothelial cells cultured on bovine collage
in the Journal of Materials Science: Materials
in Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial cells to express 2.5 times more of a specific type of collagen responsible for blood vessel formation, as compared to endothelial cells cultured on bovine collage
in Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial
cells to express 2.5 times more of a specific type of collagen responsible
for blood vessel formation, as compared to endothelial
cells cultured on bovine collagen.
«The concentrations of anabasine tested here are 100-fold lower than those required to inhibit growth of parasite
cell cultures,» Palmer - Young says, «and we did not find any evidence
for variation
in anabasine sensitivity across parasite strains.
You can look
for efficacy
in cell cultures, but that tells you almost nothing about what's going to happen when you test
in a mouse or a human.
The Mount Sinai study found that harmine drove the sustained division and multiplication of adult human beta
cells in culture, a feat that had eluded the field
for years.
«First we established an efficient method
for culturing dinoflagellate
cells in our lab,» said Shinichiro Maruyama, an assistant professor at Tohoku University.
The former Speaker — now a leading candidate
for the Republican presidential nomination — talked to DISCOVER
in 2006 about evolution, stem
cells, Washington's two
cultures, and why kids should be paid to take science and math.
«Then we
cultured the
cells in the presence of various drugs and screened
for spontaneous drug - resistant mutants to isolate clones useful
for symbiosis experiments.»
Results suggest that
cells grown
in the device exhibit more natural behaviors than when grown
in traditional
culturing methods, and the filtration by the glomerulus is necessary
for healthy
cell function.
Adoptive
cell transfer procedures are mimicking exactly this process
in a
culture dish by taking T
cells from patients, multiplying them, sometimes genetically modifying them, and then returning them to patients so that they can,
for example, locate and kill cancer
cells.
In 2016, the U.S. National Cancer Institute launched a scheme to develop more than 1000 cell culture models, including organoids, for researchers around the world to use, together with Cancer Research UK in London, the Wellcome Trust Sanger Institute in Hinxton, U.K., and HU
In 2016, the U.S. National Cancer Institute launched a scheme to develop more than 1000
cell culture models, including organoids,
for researchers around the world to use, together with Cancer Research UK
in London, the Wellcome Trust Sanger Institute in Hinxton, U.K., and HU
in London, the Wellcome Trust Sanger Institute
in Hinxton, U.K., and HU
in Hinxton, U.K., and HUB.
Using novel
culture conditions Dr. Reimer's team has shown it is now possible to maintain the
cells for 16 days
in vitro.
«
In the last few years, it has become possible to order
cultures of human
cells for testing, but they're grown on a plate, a two - dimensional environment,» says Radisic.
In this study, she and her colleagues used cell cultures collected from 16 patients in the United States and Europe to search for drugs that could kill or stop the growth of DIPG cell
In this study, she and her colleagues used
cell cultures collected from 16 patients
in the United States and Europe to search for drugs that could kill or stop the growth of DIPG cell
in the United States and Europe to search
for drugs that could kill or stop the growth of DIPG
cells.
Around the same time, Yoshiki Sasai of the RIKEN Center
for Developmental Biology
in Kobe, Japan,
cultured the first brain organoids, starting not with adult stem
cells but with embryonic stem
cells.
The researchers were able to demonstrate,
for instance, that factors responsible
for hypertrophy — enlargement of cardiac
cells for instance
in athletes and pregnant women — also led to a growth
in volume
in the cardiac
cells that had been
cultured on a film of eADF4 (κ16).
Set up experiments
for whole week: Start
cell cultures, book microscopes, make buffers, and even find time over the bacterial incubator
for a spot of eyelash fluttering at the sexy postdoc
in the lab next door.
To determine whether L1CAM has a role
in cancer, the researchers looked
for its protein
in normal skin
cells,
cultured noncancerous
cells, and aggressive melanomas from 11 patients.
To test the suitability of guanabenz as a potential treatment
for MS, Popko and his team exposed
cultured oligodendrocyte
cells to interferon gamma — a molecule that increases inflammation — resulting
in greatly increased myelin loss and
cell death.
The team then
cultured the
cells for several months
in a bath of growth - promoting proteins, trying to get the
cells to reverse course and become more like stem
cells.
Now
in the future they would love to be able to use the person's own
cells — let's say scar repair later — but
for the short - term applications these would be commercially available
cells that are kept
in cell culture ready to go.
Kass developed the midstream urine test (still used when you pee
in a cup) and set a numerical cutoff
for the number of bacteria
in normal urine: not more than 100,000 colony - forming units (
cell clusters on a
culture dish) per milliliter of urine.
Using quantitative mass spectrometry to search
for proteins that contained these stable isotope labels, researchers were able to determine the
cell of origin of both intracellular and secreted proteins identified
in multicellular
culture.
Because hers were the first human
cells cultured continuously
for use
in research, Lacks» identity was revealed
in a scientific journal
in 1971
in reference to the landmark accomplishment.
The researchers activated the TRPV1 receptor
in the
cell culture with capsaicin or helional, by adding the substances to the
culture for a period of several hours or days.
In contrast to other
cultured cells, such tumor
cells can divide indefinitely and a
cell line can therefore be
cultured for many years.
That has led scientists
in the last decade or so to look
for ways of
culturing cells in laboratory settings that are a bit more complex.
For example,
cell culture or biological analysis, which are conducted
in biology laboratories, can be performed on a microfluidic chip.
The scientists say their gadget provides a quicker diagnosis that today's typical method,
in which a
cell sample is taken and
cultured in the lab to look
for the presence of the Candida albicans fungus.