Sentences with phrase «cells in different organs»

Willet, Mills, and their colleagues believe the discovery that cells in different organs go through the same process to become proliferative could lead to new potential targets for cancer treatment because the factors that initiate tumours could be the same in multiple organs.
«Our finding that tumor cells secrete these three distinct nanoparticles, that then target cells in different organs reflects this important aspect of the disease.»

Not exact matches

Based on animal models, including a primate model, it is hypothesized that the cells remain unharmed in the digestive tract of the infant then enter the bloodstream, migrate to different organs, and there provide active immunity.54
Remarkably, given the complexity of the kidney, the cells differentiated into exactly those required in the different compartments of the organ.
«If ctenophores diverged first, these organ systems likely have been present in the common ancestor of all animals — and sponges and placozoans must subsequently have lost them — or complex traits like nerve cells and muscles must have emerged independently several times in different lineages,» Wörheide explains.
Although blood cells serve multiple roles in the body and have complex interactions with other cellular materials, most synthetic blood products have aimed to just stick to the bare basics — shuttling oxygen from the lungs to different vital organs and then bringing carbon dioxide back to the lungs to be exhaled.
Another challenge is producing stem - cell - derived tissues or organs that don't develop teratomas — tumors that contain a variety of tissues found in different organs — when transplanted.
Plotting the total number of stem cell divisions over a lifetime against the lifetime risk of cancer in 31 different organs revealed a correlation.
The Arabidopsis thaliana plant root, used in these studies, is a quite simple organ, in which cells with different functions are separated.
Recent advances in single - cell genomics technology has made it possible to separate individual cells from different tissues and organs, and measure the sets of RNA messages — called the transcriptome — which help give each cell its own identity.
Stem cell populations reside in areas called niches deep within different types of organs.
As «immature» somatic cells, stem cells can mature into different types of cells, thus making them responsible for the development of all the tissues and organs in the body.
The way these cells organize themselves structurally in different organ systems helps them coordinate their amazingly diverse behaviors and functions, keeping the whole biological machine running smoothly.
He was particularly interested in creating the simplest of solid organs, a phallus, which has just two different kinds of cells to manage.
Stem cells are non-specialized cells found in different organs.
Moreover, these stem cell - derived cells released different amounts of hormone in response to known feedback signals generated by other organs in the body.
Earlier research has been limited to the study of certain organs or a handful of cells, and has therefore not been able to definitively demonstrate the presence of specificity in the system, whereby different cell types would have different functions.
Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.
Cells in five different organs had died and other cells were expressing proteins associated with radiation respoCells in five different organs had died and other cells were expressing proteins associated with radiation respocells were expressing proteins associated with radiation responses.
We capitalized on one of the innate responses of microvascular endothelial cells, i.e., the up - regulation of cell adhesion molecules in response to inflammatory agents, to generate endothelial cell lines from different organs.
The organization of these tissues let different cell types work together, to enable organs in the body to perform their functions.
The selection strategy targeted cell populations expressing the inducible endothelial cell adhesion molecules, E-selectin and VCAM - 1, and proved successful in generating microvascular endothelial cell lines from a number of different organs.
The study also shows that viral infection also causes major adaptations in the tumour cell, and that virus - positive tumours from widely different organs can therefore display considerable similarities.
However, efforts to examine the in vitro behavior of tumor cells with endothelial cells from different anatomical regions have been prohibited because, in large part, of the limited number of organ - derived endothelial cell lines available for study.
«All epithelial cells — and that's the cells that make up most of the organs in our bodies — can do this, so you could imagine that this type of local chamber could be forming transiently in many different parts of the body, whenever cells need to self - organise and communicate,» Gilmour says.
Efforts to study the molecular mechanisms that mediate these complex processes in different anatomical compartments have been impeded by difficulties in the isolation and propagation of endothelial cells from different organs.
The immortalized endothelial cell lines established from H - 2Kb - tsA58 mice provide, for the first time, a cell culture system to examine factors regulating angiogenesis and tumor cell arrest in different organ systems.
In other studies, however, using cell lines either in vivo or in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organIn other studies, however, using cell lines either in vivo or in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organin vivo or in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organin vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organs.
But if, as this study suggests, the way that cells become proliferative again is similar across many different organs, we can imagine therapies that interfere with cancer initiation in a more global way, regardless of where that cancer may appear in the body,» he explains.
The first part of this chain has proved most challenging, especially in organs composed of a multitude of different cell types.
While he does not favor the current moratorium, Ding said, he believes scientists in this field must move slowly because «we don't know how to precisely control where and how [cells] might contribute» to different organs.
To directly evaluate the relationship between ABL family kinases and metastasis, we analyzed ABL1 and ABL2 protein abundance in MDA - MB - 231 — derived breast cancer cell lines with different organ metastasis tropisms (19).
According to the grant's description, «the communication required to establish the symbiosis between two widely different species occurs between cell layers in tissues, between organs in the plant, and across a time span from hours to days.»
LA JOLLA — Rapid advances in the ability to grow cells, tissues and organs of one species within an organism of a different species offer an unprecedented opportunity for tackling longstanding scientific...
Other cells are multipotent, meaning they can generate a few different cell types, generally in a specific tissue or organ.
For decades, scientists have been seeking a new type of vaccine that activates another player in the immune system called a T cell to fight off infections within different organs.
Different sensory systems are discussed to process stress - related social chemosignals in rodents (grueneberg ganglion cells [4], the vomeronasal organ [5], olfactory receptors [6], and trace - amine - associated receptors [7]-RRB-.
A drug that prevents myosin from working in cancer cells could keep them from invading other cells or metastasize into different organs.
LA JOLLA — Rapid advances in the ability to grow cells, tissues and organs of one species within an organism of a different species offer an unprecedented opportunity for tackling longstanding scientific mysteries and addressing pressing human health problems, particularly the need for transplantable organs and tissues.
«In addition to the sensory cells and sinus structures that allow them to process odors in the air, they also have an organ we do not have,» says Brian Ogle, a science instructor specializing in zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detecIn addition to the sensory cells and sinus structures that allow them to process odors in the air, they also have an organ we do not have,» says Brian Ogle, a science instructor specializing in zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detecin the air, they also have an organ we do not have,» says Brian Ogle, a science instructor specializing in zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detecin zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detecin Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detecin the air that we can not detect.
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