Willet, Mills, and their colleagues believe the discovery that
cells in different organs go through the same process to become proliferative could lead to new potential targets for cancer treatment because the factors that initiate tumours could be the same in multiple organs.
«Our finding that tumor cells secrete these three distinct nanoparticles, that then target
cells in different organs reflects this important aspect of the disease.»
Not exact matches
Based on animal models, including a primate model, it is hypothesized that the
cells remain unharmed
in the digestive tract of the infant then enter the bloodstream, migrate to
different organs, and there provide active immunity.54
Remarkably, given the complexity of the kidney, the
cells differentiated into exactly those required
in the
different compartments of the
organ.
«If ctenophores diverged first, these
organ systems likely have been present
in the common ancestor of all animals — and sponges and placozoans must subsequently have lost them — or complex traits like nerve
cells and muscles must have emerged independently several times
in different lineages,» Wörheide explains.
Although blood
cells serve multiple roles
in the body and have complex interactions with other cellular materials, most synthetic blood products have aimed to just stick to the bare basics — shuttling oxygen from the lungs to
different vital
organs and then bringing carbon dioxide back to the lungs to be exhaled.
Another challenge is producing stem -
cell - derived tissues or
organs that don't develop teratomas — tumors that contain a variety of tissues found
in different organs — when transplanted.
Plotting the total number of stem
cell divisions over a lifetime against the lifetime risk of cancer
in 31
different organs revealed a correlation.
The Arabidopsis thaliana plant root, used
in these studies, is a quite simple
organ,
in which
cells with
different functions are separated.
Recent advances
in single -
cell genomics technology has made it possible to separate individual
cells from
different tissues and
organs, and measure the sets of RNA messages — called the transcriptome — which help give each
cell its own identity.
Stem
cell populations reside
in areas called niches deep within
different types of
organs.
As «immature» somatic
cells, stem
cells can mature into
different types of
cells, thus making them responsible for the development of all the tissues and
organs in the body.
The way these
cells organize themselves structurally
in different organ systems helps them coordinate their amazingly diverse behaviors and functions, keeping the whole biological machine running smoothly.
He was particularly interested
in creating the simplest of solid
organs, a phallus, which has just two
different kinds of
cells to manage.
Stem
cells are non-specialized
cells found
in different organs.
Moreover, these stem
cell - derived
cells released
different amounts of hormone
in response to known feedback signals generated by other
organs in the body.
Earlier research has been limited to the study of certain
organs or a handful of
cells, and has therefore not been able to definitively demonstrate the presence of specificity
in the system, whereby
different cell types would have
different functions.
Different types of tumors show a preference for specific
organs and tissues; circulating breast cancer
cells, for example, are likely to take root
in bones, lungs, and the brain.
Cells in five different organs had died and other cells were expressing proteins associated with radiation respo
Cells in five
different organs had died and other
cells were expressing proteins associated with radiation respo
cells were expressing proteins associated with radiation responses.
We capitalized on one of the innate responses of microvascular endothelial
cells, i.e., the up - regulation of
cell adhesion molecules
in response to inflammatory agents, to generate endothelial
cell lines from
different organs.
The organization of these tissues let
different cell types work together, to enable
organs in the body to perform their functions.
The selection strategy targeted
cell populations expressing the inducible endothelial
cell adhesion molecules, E-selectin and VCAM - 1, and proved successful
in generating microvascular endothelial
cell lines from a number of
different organs.
The study also shows that viral infection also causes major adaptations
in the tumour
cell, and that virus - positive tumours from widely
different organs can therefore display considerable similarities.
However, efforts to examine the
in vitro behavior of tumor
cells with endothelial
cells from
different anatomical regions have been prohibited because,
in large part, of the limited number of
organ - derived endothelial
cell lines available for study.
«All epithelial
cells — and that's the
cells that make up most of the
organs in our bodies — can do this, so you could imagine that this type of local chamber could be forming transiently
in many
different parts of the body, whenever
cells need to self - organise and communicate,» Gilmour says.
Efforts to study the molecular mechanisms that mediate these complex processes
in different anatomical compartments have been impeded by difficulties
in the isolation and propagation of endothelial
cells from
different organs.
The immortalized endothelial
cell lines established from H - 2Kb - tsA58 mice provide, for the first time, a
cell culture system to examine factors regulating angiogenesis and tumor
cell arrest
in different organ systems.
In other studies, however, using cell lines either in vivo or in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organ
In other studies, however, using
cell lines either
in vivo or in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organ
in vivo or
in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organ
in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to
different organs.
But if, as this study suggests, the way that
cells become proliferative again is similar across many
different organs, we can imagine therapies that interfere with cancer initiation
in a more global way, regardless of where that cancer may appear
in the body,» he explains.
The first part of this chain has proved most challenging, especially
in organs composed of a multitude of
different cell types.
While he does not favor the current moratorium, Ding said, he believes scientists
in this field must move slowly because «we don't know how to precisely control where and how [
cells] might contribute» to
different organs.
To directly evaluate the relationship between ABL family kinases and metastasis, we analyzed ABL1 and ABL2 protein abundance
in MDA - MB - 231 — derived breast cancer
cell lines with
different organ metastasis tropisms (19).
According to the grant's description, «the communication required to establish the symbiosis between two widely
different species occurs between
cell layers
in tissues, between
organs in the plant, and across a time span from hours to days.»
LA JOLLA — Rapid advances
in the ability to grow
cells, tissues and
organs of one species within an organism of a
different species offer an unprecedented opportunity for tackling longstanding scientific...
Other
cells are multipotent, meaning they can generate a few
different cell types, generally
in a specific tissue or
organ.
For decades, scientists have been seeking a new type of vaccine that activates another player
in the immune system called a T
cell to fight off infections within
different organs.
Different sensory systems are discussed to process stress - related social chemosignals
in rodents (grueneberg ganglion
cells [4], the vomeronasal
organ [5], olfactory receptors [6], and trace - amine - associated receptors [7]-RRB-.
A drug that prevents myosin from working
in cancer
cells could keep them from invading other
cells or metastasize into
different organs.
LA JOLLA — Rapid advances
in the ability to grow
cells, tissues and
organs of one species within an organism of a
different species offer an unprecedented opportunity for tackling longstanding scientific mysteries and addressing pressing human health problems, particularly the need for transplantable
organs and tissues.
«
In addition to the sensory cells and sinus structures that allow them to process odors in the air, they also have an organ we do not have,» says Brian Ogle, a science instructor specializing in zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detec
In addition to the sensory
cells and sinus structures that allow them to process odors
in the air, they also have an organ we do not have,» says Brian Ogle, a science instructor specializing in zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detec
in the air, they also have an
organ we do not have,» says Brian Ogle, a science instructor specializing
in zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detec
in zoos, aquariums, animal shelters, human - wildlife contact, and pet / animal ownership at Beacon College
in Leesburg, FL. «This organ is called a Jacobson's organ, which helps to analyze different chemicals in the air that we can not detec
in Leesburg, FL. «This
organ is called a Jacobson's
organ, which helps to analyze
different chemicals
in the air that we can not detec
in the air that we can not detect.