Sentences with phrase «cells in lab»

Half a continent away, Buckanovich was doing his own studies on the role that the same protein played in the growth of ovarian cancer cells in his lab at the University of Michigan.

Eward, Fogle and their colleagues already have some evidence in support of this idea based on preliminary studies they've conducted in mouse models and cells in the lab.

This study found that turmeric extract reduced the growth of certain types of cancer cells in a lab setting.

A group of researchers at the Baylor College of Medicine has published the results of a study in the journal PLoS ONE demonstrating that a concentrated form of the compound sulforaphane found in broccoli and other cruciferous vegetables has been shown to reduce the number of acute lymphoblastic leukemia cells in a lab setting.

They grew pancreatic cancer cells in lab dishes and fed them both glucose and fructose.

But this humble substance has also been studied for its biological activity against more serious matters like cancer cells in lab tests.

Studies about the benefits of Resveratrol have typically looked at how it affects cells in a lab setting.

Using tumour cells in the lab, as well as mini lab - grown tumours called organoids, Coleman hopes to reveal more about the role these faulty molecules — called protein «hydroxylases» — have in cancer.

We developed a way of getting siRNAs into epithelial cells by either mixing them with a transfection lipid used to introduce exogenous nucleic acids into cells in the lab or by adding a cholesterol tag to the end of the RNA sequence that allowed the RNA to be taken up into cells.

They were then able to multiply the harvested lung cells in the lab to yield enough cells sufficient for human therapy.

They tested the effects of eight commercial drinks containing nano - size metal or metal - like particles on human intestinal cells in the lab.

Creating human lung epithelial cells in the lab has been a challenge, and lineage - specific reporters, which indicate each cell's specific type, are key to understanding lung epithelial stem cell development.

Researchers at Boston Children's Hospital have, for the first time, generated blood - forming stem cells in the lab using pluripotent stem cells, which can make virtually every cell type in the body.

And to do so, Ottersbach and her team are trying to understand how the disease might begin, even before birth, by looking at cells in the lab as well as young mice with the disease.

«The problem is that brain cells from actual people don't survive well in a dish, so we need to engineer human cells in the lab,» explained Gan, senior investigator at the Gladstone Institutes.

But culturing germ cells (the process of growing these specialized cells in the lab) is difficult, and scientists have not yet been able to culture the germ cells of pigeons.

We investigate organoids, the latest way that scientists are growing cancer cells in the lab to help test hundreds of cancer drugs.

Bradner's team showed that an existing TRIM24 binder can be used to make a TRIM24 protein degrader, which was able to take down leukemia cells in the lab.

Tests on human beta cells in the lab showed that the hormone had the same effect as in isolated rat beta cells.

«I thought that if our team could find a way to simplify and better control that approach, we might be able to improve the way we engineer human brain cells in the lab.»

Researchers are also exploring different methods to deliver stem cells to the eye, including creating patches of RPE cells in the lab.

«To make this available as a therapy, we would take a muscle biopsy from a patient with a muscle injury or disease, remove the myoendothelial cells and treat the cells in the lab.

Muehlenbachs said further study was limited by the patient's death and the fact that researchers have been unable to grow tapeworm cancer cells in the lab.

Then the team used the cells from the surgery to grow billions of cancer - fighting immune cells in the lab.

To take a finding in basic research, such as identifying a mutant protein that drives a particular cancer, and develop a drug that inactivates the protein and performs well in cells in the lab and in animal models can take years, if not decades.

Dish Life, the final of four Cambridge Shorts films, compares the task of raising stem cells in the lab to the challenge of looking after a gang of unruly kids.

Wang's team discovered that if human lung cancer cells in a lab dish in the presence of the receptor were treated with BCX, they migrated less than untreated ones.

«We needed to find a way to make millions of new cells in the lab, and then get them into the human brain,» said Studer.

Zhang has been using a different approach — studying diseased human cells in lab dishes.

Sheer mass is a major issue — it's very difficult to nourish a 3 - D population of cells in the lab on the scale of a liver.

«Since that time, Lorenz has made a significant number of transformative contributions and developed protocols that have fundamentally changed the way we create stem cells in the lab,» said Lennart Mucke, MD, director of the Gladstone Institute of Neurological Disease.

Researchers at Massachusetts General Hospital have grow a rat forearm out of living cells in the lab.

A solution, Cheng and his colleagues thought, could be to grow blood cells in the lab that were matched to each patient's own genetic material and thus could evade the immune system.

In a May 2014 study, Nagrath and colleagues found that highly aggressive ovarian cancer cells were glutamine - dependent and that depriving the cells of external sources of glutamine — as some experimental drugs do — was an effective way to kill late - stage ovarian cancer cells in the lab.

Some bone tissue had previously been generated from stem cells in the lab, but this marks hope for a surgical solution for those who need additional bone.

To identify promising compounds, the team grew human nerve cells in the lab and tested whether more than 1100 medications, vitamins, dietary supplements, and other molecules altered their output of α - synuclein.

An oral drug used to treat an illness unrelated to HIV eradicated infectious HIV - producing cells in lab cultures while sparing uninfected cells — and suppressed the virus in patients during treatment and for at least eight weeks after the drug was stopped, according to results of a clinical pilot trial and researchers at Rutgers University and Dartmouth College.

That made working with the mini-brains expensive, given the high cost of the nutrients needed to cultivate human stem cells in the lab, he says, as well as the expense of chemical growth factors that guide the tissue to organize itself like a real brain.

The team initially prepared the IPS cells in the lab and then injected them into the brain cavities of a developing mouse in the womb.

Both teams successfully used these to reprogramme skin cells in a lab dish into cells resembling embryonic stem cells, which have the ability to turn into any tissue of the human body.

The researchers inserted between 10,000 and 40,000 of these small RNAs at once into breast cancer, colon cancer, and normal human cells in the lab.

Ralph Brinster, part of the team at the University of Pennsylvania in Philadelphia that first cultured sperm stem cells in the lab, has written that culturing stem cells from human sperm is not far off — humans and mice, like other mammals, he says, require similar growth factors.

They grew the cancer cells in the lab and injected them into mice.

The Stem Cell Reports research applies those findings to human stem cells in the lab.

The team collected two small skin samples from each, and then cultured the cells in the lab and inserted the gene that makes fireflies glow into the gene that regulates the cells» clock.

Matthew Aliota, a research scientist in the UW - Madison School of Veterinary Medicine, conducted experiments with monkey saliva and cells in the lab.

To find out why these gut cells release such large amounts of a brain chemical, David Julius at the University of California, San Francisco, and his team have been studying mini-intestines grown from mouse cells in the lab.

With a tweak to the technique that cloned a sheep in 1996, scientists have generated stem cells in the lab that genetically match those found in human embryos.

Once they were able to isolate skeletal muscle cells using the newly identified surface markers, the research team matured those cells in the lab to create dystrophin - producing muscle fibers.

They cultured the cells in the lab for a day, then exposed them for 3 days to a virus which contained the normal gene for the receptor.